Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID82232 Alpha-estradiol GSE92742 HA1E Human 24h 3.32999992371uM EID0494
Types Number Response transcription factors
Up-regulation 52 NR1H2; TBPL1; GLI2; EED; FOSL2; RB1; CENPB; RORA; TSC22D1; HOXA7; SOX13; TDP2; BHLHE41; ZNF302; GATA4; KLF11; PAX6; MITF; SOX11; EGR3; TCF15; PITX1; IFI16; GATA6; HMGB2; HLF; NKX2-2; SOX17; WT1; LEF1; CREG1; INSM1; NANOG; CEBPB; FOXE1; STAT5B; MYCN; KAT2B; MAF; TGFB1I1; TGFB1; FLNA; JAK2; HEY2; HEY1; PSMC3; HOXC6; WWP1; MEIS1; HOXB7; ASCL1; IRF8
Down-regulation 79 ERBB2; HMBOX1; HDAC6; SMAD7; TRIM24; IRX5; ZNF91; RBM39; PSMC3IP; DNMT3B; BRPF1; CRYM; ID1; TRAK1; CCNE1; CTBP2; SMARCA4; URI1; IRF6; LITAF; ERBB4; SIX1; ZNF85; EP400; MTA1; HMG20A; MAGED1; BRD3; TFCP2L1; TRIM22; SMAD5; FOXC1; MLLT10; ZNF468; KDM5D; MECOM; KDM2A; FOXN3; TRIP6; ABL1; DACH1; PMS1; PPARGC1A; SLC2A4RG; ZNF606; TRPS1; HOXD1; GATAD2A; TWIST1; TBL1X; HOXB5; TOB1; ZNF43; VGLL4; FOXG1; CUX1; ZSCAN18; ESR1; KLF7; NR2F2; ATF5; NR2F1; NR3C2; HDAC9; ZMYND8; TOX3; FOSB; INSR; THAP11; KLF10; TOX; HOXB6; RBPMS; HOXC10; NFATC3; FOXO3; NR3C1; TCFL5; MEF2C