The ChemPert web interface mainly includes two sections: the database and the webtool, which reveals the relationship between external perturbations, protein targets of perturbations and downstream transcriptional signatures in non-cancer cells.
ChemPert database contains 82,270 transcriptional signatures in response to 2566 unique chemical compounds across 167 normal cell types/lines and tissues, as well as the protein targets of 57,818 chemical compounds.
To browse, search and download the ChemPert database, please go to Database page directly, or go to Download page for all datasets, without creating an account and login.
ChemPert webtool allows users either to predict the transcriptional responses given the perturbagen or predict the perturbagen targeting desired sets of transcriptional signatures based on ChemPert database.
To predict the transcriptional responses or perturbagens by using ChemPert tool, please go to Webtool page. Alternatively, you can use the source code from the gitlab repository.
This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
See the GNU Affero General Public License for more details.