Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID82150 Alpha-estradiol GSE92742 HA1E Human 24h 0.370000004768uM EID0493
Types Number Response transcription factors
Up-regulation 45 SSBP2; POU2AF1; CREG1; CCNH; CCNC; WT1; ZNF274; THAP10; LIN28A; UBE2B; SP140L; ESR1; ITGB3BP; HOXD1; LEF1; NKX3-1; IFI16; MED21; PRRX1; SUMO1; ZNF140; TRIM22; ZNF266; SMAD1; HMGN3; CREB3; TCEB2; CRYM; MDM2; RBBP8; ZHX2; COPS2; FOSL1; ZNF331; TAL1; ISL1; E2F2; AEBP1; SHOX2; ZNF423; ZFP36L1; SPDEF; HDAC2; KLF10; HOXC6
Down-regulation 63 PUF60; NFATC3; TFCP2; SSRP1; KLF5; RUNX3; TGFB1; TSC22D4; NCOA2; ZEB1; ZBED1; PLAGL1; PRKDC; CENPF; MSX1; PDLIM1; MGA; FOXF1; SMAD2; BCOR; KLF6; ELF3; CREB3L2; TRRAP; SMARCA5; ZNF7; RUVBL2; KLF4; PBX1; KLF9; FOXG1; NCOA1; TSC22D2; RBPJ; MNAT1; WWTR1; ZFPM2; ATF1; TBL1X; PEG3; STAT5B; TP63; MAF; CUX1; SMAD7; FOSB; ABL1; AHR; HTATIP2; SOX9; NFIB; LITAF; HEY1; HMGA1; SNAI2; PPARD; RB1; ZBTB20; NR3C1; FOXO3; KDM5B; STAT1; NFKB2