Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID82149 Alpha-estradiol GSE92742 HA1E Human 24h 1.11000001431uM EID0493
Types Number Response transcription factors
Up-regulation 68 KDM5A; GATA3; SOX4; ZNF274; MTF2; ESR1; TRPS1; BACH2; ZNF148; ZNF430; ZNF444; ZNF91; AFF2; ZNF85; SSX1; ZIC1; PLAG1; PTTG1; BRD2; ZFP36L2; SMAD5; ZNF528; BNC2; PPARG; ZNF443; ZNF44; MITF; JUP; PCGF2; NR1D2; ZNF14; ZNF606; IRX5; MED1; CREB3L2; HIRA; ING3; CREM; OLIG2; ZNF195; NFAT5; DLX5; SPIB; SP3; PGR; ZNF665; TGIF1; SMARCD3; IL16; BTG1; NFE2L3; TSG101; ZNF43; MAGED1; KDM5D; SOX9; IRF4; RXRA; MECOM; RUNX1; FOS; ZKSCAN1; SATB2; IRF7; ZNF83; PPARD; TOX3; SPDEF
Down-regulation 68 FOXJ3; CEBPZ; ZBED1; NR2F1; RUNX3; DACH1; RCOR1; VDR; TSC22D2; MEIS1; FOXF1; TOX; ARNTL2; PRKDC; TFCP2; DR1; BTAF1; PHIP; HOXC4; KLF9; THRA; EP300; FOSL2; RNF141; HOXC10; NOC2L; BCLAF1; MECP2; TCEA1; SMAD4; YAP1; WNT4; FOXF2; MEIS2; TTF2; FLNA; SNAI2; TGFB1I1; MKL1; INSR; HOXB2; STAT5B; EMX2; INSM1; THAP11; CEBPB; TBL1XR1; ATF1; ETS2; HIPK3; KLF7; HOXC6; HOXB6; TSC22D1; FOXO3; TRIB3; FOXC1; EHF; ISL1; NR4A2; TRIM29; ZMIZ1; ARNT2; HDAC2; NR3C1; CEBPD; E2F2; NFKB2