Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID82147 Alpha-estradiol GSE92742 HA1E Human 24h 10uM EID0493
Types Number Response transcription factors
Up-regulation 73 TFDP1; IFI16; POU2AF1; CDC5L; NKX3-1; POU4F2; MED20; THAP10; SOX2; THAP1; FLI1; FOXG1; KLF11; THRA; TCF12; HDAC4; POU4F1; SSX1; ITGB3BP; HDGF; SP140L; NR2E1; HMGB3; C1QBP; CCNC; NFE2; HOXD10; AIP; SUB1; MED6; MTDH; SHOX2; SUMO1; HOXB7; SP100; PHOX2B; PAX5; CTR9; TAF9B; MNDA; USF2; KDM5D; HMGN3; TOB1; TRIM22; FOSL1; MDM2; ID3; IRF9; TCF7; GATA6; HOXD1; BRD4; HLX; ZNF544; RHOA; PIR; MYRF; HDAC9; TAL1; ZNF410; KLF10; FOXD1; EGR3; HHEX; STAT1; SNAI2; KLF2; SATB2; ID1; SPDEF; HDAC2; HES1
Down-regulation 92 XBP1; NFATC3; SMAD3; TP53; DMTF1; FOXF1; NR2F6; FUBP1; MSX1; TSC22D2; PBX1; MEIS1; MYOG; TGFB1; PEG3; SRCAP; KLF9; PAX6; PHF2; AHR; TULP4; BAZ2B; PHIP; L3MBTL1; NEUROD1; TCF15; BRD7; KLF5; ZFPM2; TSC22D4; EDF1; SAFB; RERE; FLNA; TLE2; NKX2-2; CREB3L2; BBX; ELF5; WWC1; TRPS1; PURA; NANOG; ID4; TRIP6; MGA; SALL2; ZNF189; ENO1; MAF; SMARCA1; ZNF165; ZIC1; NFIB; ING3; KLF6; TRRAP; ZMYND8; STAT5B; ELF2; SMAD4; SOX17; TBX3; TGIF2; YAP1; ZNF83; CUX1; IRF8; THAP11; LITAF; BCL6; HSBP1; HIPK3; SOX9; CEBPB; GTF2IRD1; ZNF562; ZBED2; ATF1; CITED2; IRF6; BHLHE41; ZBTB20; TBL1XR1; MECOM; TCF4; NR3C1; PPARD; FOXO3; CEBPD; E2F2; NFKB2