Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID82135	Barasertib-hqpa	GSE92742	HA1E	Human	24h	10uM	EID0493

Response Information :

Types	Number	Response transcription factors
Up-regulation	142	SOX2; GATA2; POU2AF1; BACH2; SPEN; SOX4; NFKBIB; ZNF274; MYB; IRF4; MYOD1; TFDP1; SSX1; TAF1D; OSR2; ZNF536; SIAH2; GLI3; PBX1; RORA; ARID5A; FLI1; IFI16; MKL2; MLXIP; NEUROD6; SIRT2; ZBTB18; HMGB3; SP140; SP110; ZBTB44; ZNF267; SREBF1; GABPB1; FOXK2; SOHLH2; PRDM1; CERS4; PRDM2; MAFF; MXD3; WHSC1L1; ZNF107; NR2F2; CRYM; AEBP1; HCFC2; ZKSCAN7; HIVEP3; EGR1; HMGA2; ZEB2; HDAC9; FOXO1; CREB5; TAF5; PMF1; ZNF215; NFE2L3; PCGF2; VDR; TTF1; ZNF195; RFX5; IRF2; SETD2; LMCD1; PRRX1; EGR3; HOXA11; ZNF302; TFEB; SREBF2; TCF7L2; HMGXB4; TRPS1; ZNF232; BATF3; RSF1; NR0B2; PLAG1; ZBTB16; PAX5; HMG20B; BCL11A; PCBD1; ZFPM2; RBBP7; ZIC1; ESR1; PBXIP1; BPTF; PITX2; SKI; HDAC4; EYA1; TRIM32; NOC2L; NFAT5; CBFB; MNT; SAP30; CTR9; SMARCD3; NAB2; HIPK2; ZFHX4; NR1H4; PLAGL2; TXNIP; USF2; FOSB; FOXE1; MED24; YBX3; CRY1; MEIS2; ZBED2; RBPMS; ZHX3; COPS2; SHOX2; OLIG2; SOX13; RBPJ; KDM5D; CBX3; THAP11; TOX3; FOSL1; ZMYND8; RHOA; RARA; HHEX; MAGED1; FOXG1; ARID4B; HOXC6; LITAF; SPDEF; KDM5B
Down-regulation	188	FOXJ3; DMTF1; TGFB1; TLE1; BIRC2; FOXF1; SFPQ; IKBKAP; TSC22D2; CREB1; CCNC; RCOR1; CEBPA; WDR77; ATF5; NR2F6; FOXF2; ZNF623; MED13; ZNF12; ZNF217; HIPK1; SMAD4; ZNF430; BRD3; CAPN15; YBX1; RFXANK; ZNF91; PHIP; ZFP36L2; NFE2L1; PSIP1; ZNF148; BRD2; CTNNB1; PRKDC; LIN28A; BBX; CSDE1; KLF9; TCEA1; CHAF1B; SOX9; NRBF2; REST; CIZ1; PNRC1; ZNF248; RYBP; ZMYM2; KLF5; YWHAB; MEIS1; NSD1; TDP2; HNRNPD; TEAD4; HLTF; DNMT3B; TSC22D4; TWIST1; ZBTB3; ZBTB38; NEUROD1; TCFL5; SUPT3H; GATA3; LOXL2; YAP1; ERBB4; HOXA1; ERF; PIAS2; MED15; MBD2; UBE2L3; NONO; BAZ2A; CNOT3; MXI1; SMAD1; SMARCA1; PTRF; IRF1; NR3C2; PSMC3IP; NCOA4; ZNF7; ZBTB7A; MYCL; RNF111; ZNF506; FLNA; ATF1; MED16; DLX4; SF1; SNW1; HDAC2; ORC2; UBTF; BCLAF1; CEBPB; RREB1; DDX5; UBE3A; DEK; SOX17; TRIM27; FUBP1; SAFB2; TULP3; PAX6; ID3; BTAF1; ZNF573; TLE2; KLF6; MTA1; JUND; TAF9B; EHMT2; NR1D2; GTF2I; SMAD6; BHLHE41; BCL11B; DBP; SIX1; BRD4; HMGN3; HES1; JUNB; ZNF189; MNDA; PMS1; NRIP1; MED6; EPAS1; JUP; EMX2; DACH1; SERTAD2; NR4A2; TOX; RNF14; HIC2; DDIT3; HIRA; CTBP2; TGIF1; ZNF331; ST18; ZNF394; ZNF562; STAT5B; CNBP; ENO1; TFDP2; FOXD1; ZSCAN18; AHR; ZNF165; WWTR1; SMAD7; EHF; GATA6; ID1; ZNF423; ZNF83; ABL1; REL; ZNF532; FOS; ID4; ZMIZ1; TOB1; MECOM; FOXO3; CITED2; KLF10; STAT1; PPARD; BASP1; E2F2; NR3C1; CEBPD