Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID82015	Doxorubicin	GSE92742	HA1E	Human	24h	10uM	EID0497

Response Information :

Types	Number	Response transcription factors
Up-regulation	135	NFKBIB; ETV1; ZNF586; WWP1; TFAP2C; E2F2; SERTAD2; SOHLH2; TAF9B; MEF2C; NFYB; SP110; ZNF711; PBXIP1; NFE2L3; TDP2; PEX14; DLX2; VGLL1; SP140L; GATA6; EHF; GABPB1; ZNF345; NR1H3; TFAP2A; ZNF770; NUP62; RFXANK; ZMYND8; ETS1; NR2C1; TGIF1; RNF14; GTF2I; ZNF154; MED20; PBX3; JUND; TAF1A; HIRA; SIX3; HMGB2; ZNF593; SSX1; ZNF337; RSF1; WWC1; WNT4; TAF6L; ZBED2; KLF11; ZFPM2; ZNF268; CREM; CARF; TRPS1; NFYA; ELK4; ZNF331; SOX5; SIN3B; CSDE1; ENY2; FOXO1; CDYL; MYRF; E2F5; NR5A2; CDIP1; OVOL2; ZNF141; PRDM2; ZNF232; AR; TSC22D3; ATF3; NR4A2; PRRX1; ZBTB16; ZHX2; CDK8; CREBL2; TAF4B; TSC22D1; LITAF; RBPMS; ISL1; SIAH2; NANOG; DAXX; ZNF589; CERS4; FOXA2; HDAC9; RUNX3; SOX2; NAB2; HOXA1; FOXF2; RUNX1; HOXD1; PGR; FUBP1; KMT5A; SOX10; CITED1; PSMC3; SP100; ZBTB17; MYB; AEBP1; HBP1; SPIB; LMCD1; ZNF239; CITED2; PHF1; MKL2; ZXDC; STAT4; ZNF623; STAT1; ZNF195; NKX2-2; ZEB1; NR2F6; YAP1; KLF9; ZNF165; SNAI2; HHEX; CREB1; SPDEF; RHOA
Down-regulation	196	GLI2; FHL2; ARID4B; MYC; APBB1; KAT8; NFIL3; TGFB1I1; NFATC4; KLF7; MAZ; GTF2IRD1; RYBP; CRK; CIC; VGLL4; TFDP1; SUV39H1; CHD9; TP53; CXXC1; EZH2; ATN1; ERBB2; HSBP1; ERCC2; MYCN; HOXA10; ZNF629; ZNF410; SMAD7; NFKBIA; RAN; HMX1; TAF10; ZNF443; MAML1; HCFC1; NEDD8; RELA; CNOT1; NFATC3; KMT2B; HOXC10; MSX1; ATF4; ETV5; HMGXB4; CCNE1; GLI1; AATF; PITX2; HDAC7; RNF111; PAX8; TSC22D2; KDM2A; PTTG1; ZNF536; ZNF646; HNRNPD; USP21; SREBF2; NCOR2; ZNF217; PA2G4; PPRC1; HOXA7; SAP130; YEATS4; TRIM28; XBP1; CTCF; CNOT2; BASP1; USP22; ZNF692; SND1; TLE4; MED13; PAX5; TSC22D4; KDM4C; EMX2; ZBED1; SF1; FOXJ3; SMAD1; SIRT2; MED15; ZZZ3; CCDC59; BCOR; EP300; RUVBL2; ZNF248; ZNF574; ELF4; PATZ1; NFKB1; SUPT6H; BATF3; TAF7; POU5F1B; IKBKAP; BAZ1A; POLR2A; FOXD1; ECD; HDAC1; ADNP2; KAT7; ITGB3BP; RLF; BAZ1B; MKL1; ID2; HAND1; EVX1; HR; TCF15; ZNF107; MAF; SALL1; POU4F1; ZNF148; TCF4; ASCL1; CCNC; ZNF124; ZNF423; MAGED1; WIZ; SIX1; EGR2; PCGF1; CDX2; MYOG; PLAGL1; ERG; DNMT3B; ZNF32; ZNF189; HMGB3; ELK3; APEX1; HOXB7; RNF138; HDGF; BRD2; PQBP1; HDAC2; YBX1; PAX6; FOXC1; ZNF91; MEIS1; HLTF; PUF60; PIAS2; HOXB6; BAZ2B; DDIT3; VEZF1; KDM5C; NFIB; ESRRA; FOXM1; SMARCA4; BNC2; ZBTB38; RBBP4; ZFP36L1; TFDP2; ZBTB1; NRBF2; HIPK1; NR1D2; HOXA11; MEOX2; DACH1; FOSL1; NR3C1; BRD4; SSBP2; SCAND1; CTBP2; ZEB2; ID1; ZNF274; ZIC1; NRIP1; MEIS2; HLX; MNAT1; CEBPD