Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID81994 Trequinsin GSE92742 HA1E Human 24h 1.11000001431uM EID0497
Types Number Response transcription factors
Up-regulation 128 RNF6; KMT2A; ZNF586; MTF2; NR4A1; ZNF593; TAF11; ZNF32; KLF10; ETS1; TDP2; MED7; TDRD3; PBX1; C1QBP; SUPT4H1; SAP18; ZNF337; TFDP2; ZNF226; NR0B1; DEK; ABT1; TLE2; NR1H2; KLF13; MYB; SP110; TFAP2C; FLNA; ZNF770; ATF3; UTF1; HOXC10; THAP1; LHX6; ZNF202; E2F3; RBL1; DLX2; CRY1; PFDN5; MKL2; KLF11; PSMC3IP; ZNF107; ZNF589; NR5A2; TSC22D3; TRIP4; PRDM10; BCL10; NR4A2; ZNF532; EGR2; EDF1; ZNF140; MITF; VEZF1; NKRF; TFAM; HIRA; DNAJC1; POLR3C; ZNF652; SUMO1; UBE2I; BHLHE40; NKX2-2; TAL1; CUX2; PGR; KLF5; SOX2; RORA; LMCD1; MED14; COPS2; ARNTL; ETS2; ERBB4; TRIM16; BRF2; UBE2B; ASH2L; BIRC2; FOXN3; HOXB5; HOXD11; TAF12; CEBPG; NFE2L3; STAT1; FUBP1; CERS6; CDK8; HOXD1; ZNF232; ESR1; ZBTB16; IRF1; ARL2BP; DLX5; SFPQ; LEF1; CREB1; ZNF195; CREM; TRIP6; ZFP36L1; FOXG1; SPDEF; ZNF331; RBBP4; AFF1; DMTF1; HOXA10; ZNF239; ZNF22; KLF6; HTATIP2; HOXB7; HOXB2; TBX3; HOXB6; TBX2; MEIS1; EED
Down-regulation 98 GLI2; ARID4B; TGFB1I1; GTF2IRD1; CALR; KLF7; ASCL1; CXXC1; ZBTB18; CHD9; ZNF629; ATN1; MYCN; RUVBL2; MYC; CEBPB; NR2F6; CHD7; KLF2; NUP62; FOXD1; MAF; HR; PAXBP1; PURA; PAX5; SOX9; KLF3; ZNF444; ESRRA; VGLL4; SMAD7; HDGF; TCF25; RARA; VPS72; ISL1; REL; ZNF217; ZNF587; CCNE1; LOXL2; CLOCK; ZHX2; KDM4C; POU4F1; NCOR2; CUX1; RBFOX2; MSX1; ID4; SCMH1; TOX3; IRF8; ERF; KAT2B; GATA6; PITX1; ZNF423; FOXJ3; ID1; MYRF; POU2AF1; SSBP2; TCF7L1; HDAC7; YBX1; SMARCA1; TXNIP; FOXF1; HIPK3; TRIM22; TLE4; BHLHE41; SSBP3; ZEB1; MLXIP; SALL1; SOX11; WT1; PCGF1; NR1H4; SOX13; SLC2A4RG; HHEX; STAT6; ZNF274; CREB3L1; PEG3; ZIC1; ZFHX4; TCF7L2; FOSL1; NR3C1; AHR; MNAT1; RB1; CEBPD