Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID81648	Vorinostat	GSE92742	HEK293T	Human	24h	10uM	EID0233

Response Information :

Types	Number	Response transcription factors
Up-regulation	160	KDM5B; ADRB2; HMG20B; DRAP1; SOX2; SOX4; PPARD; FOXO4; EZH2; HBP1; RHOA; NFIL3; OSR2; ZNF331; SP110; STAT3; GTF2A2; BCL3; RYBP; TBPL1; BCL10; CERS4; GMNN; HABP4; CBX4; UBE2B; HES1; ATF3; ARID4B; ING1; CDK7; HCFC2; LDB1; SIX1; DDIT3; MNAT1; RELB; BRD4; BRF2; JUNB; NEDD8; ARNTL; KLF5; ETV1; ETV5; ETS1; NCOA3; NR4A1; TBP; SMAD2; CITED2; IRF3; TEAD3; SPIB; ARID5A; NR0B1; DR1; PIAS1; BTG1; ID2; GATA2; NRBF2; TCEA2; POU2F2; MYCBP; RBBP5; HINFP; MAFG; JUND; AFF4; RUNX3; MYCN; SNIP1; PAWR; TCF21; CTR9; SNAI1; ZNF443; BRD2; KLF10; RCOR1; ING4; SUZ12; BIRC2; IRF8; YBX2; MTF2; ZNF224; ZNF212; ZNF117; ZNF79; TOB1; TSC22D2; ATF7IP; ZNF274; KLF7; PNRC1; CREM; SND1; TCF7; IRF7; HSF2; FOXJ3; CCNE1; CREB3; HSBP1; ZNF3; ZMIZ2; ZNF85; CEBPB; TOX; ZNF410; PHF1; CTBP2; RUVBL2; ZBED2; CRK; TFDP2; SSBP2; PIAS2; CRYM; SIRT7; NR5A2; PBXIP1; ARNT2; FOSB; KLF6; RLF; TCF15; HOXD1; EGR3; NR3C2; CARHSP1; AHR; INSR; SETD3; TBX3; GATAD2A; LMCD1; TFAP2C; CEBPE; CD3D; ZNF329; MKL1; CRY1; ARID5B; SUMO1; ELF3; MYBL1; SUPT4H1; TERF2; IRF9; ZFHX4; ZNF91; ZNF211; FOS; ZNF44; DNAJC1; FOXK2; ADNP2
Down-regulation	252	MYC; ATF1; PCBD1; MTA1; MYBL2; TSC22D3; HOXA5; PPARG; RFX5; NRIP1; TP53; PHF2; SPEN; CCNA2; TFDP1; ZFP64; SMARCC1; PMF1; SUV39H1; ZMIZ1; VPS72; NUP62; USP22; C1QBP; FOXM1; XBP1; HMGA2; DEAF1; CBX5; WDR77; BCLAF1; SMARCA4; TFAP2A; ABL1; HMGB2; SETDB1; SALL1; ADNP; HOXA10; TCERG1; PRMT2; MED24; MEIS2; BRD7; ATN1; TRIP6; ERBB2; ALX1; RAN; SMAD3; NFKB1; ZBTB38; MED16; GTF2IRD1; TEAD4; NCOR1; DDX17; ATF5; MYBBP1A; CHD9; SSRP1; PHF8; PATZ1; ZHX2; EP400; ZMYND11; RBM14; UBE3A; ZNF140; SIX2; KAT5; STAT5B; ZNF384; ZZZ3; CHD7; SIAH2; ZBED1; ZBTB14; GCFC2; ZNF282; MED12; NRF1; FOXJ2; UBP1; ZNF16; ZSCAN31; ARNT; NAB1; NFKBIA; CSDE1; SCMH1; STAT6; HSF1; BCOR; USP21; CAPN15; ID4; CAMTA2; ARL2BP; PBRM1; KAT2A; THAP4; HOXB9; STAT5A; ZNF146; RXRA; ORC2; ZNF580; TCEA1; HDGF; YBX3; PURA; ZBTB1; ZNF629; RREB1; NCOA2; BAZ2B; NFYC; XRCC6; ELF1; CENPB; CBX3; ZNF33B; RBFOX2; HCFC1; SFMBT1; TCF25; SMARCE1; PCGF2; NHLH2; MLLT10; ZNF473; TTF2; PPRC1; DEK; LMO1; CBFB; NEUROD1; DDX54; HNRNPD; SMARCD1; PRDM13; MAZ; FOXA2; GTF3A; TAF1D; CNBP; BRCA1; ELF4; HLF; PQBP1; TRRAP; TFAP4; E2F5; ZFP69B; DNAJC2; DDX5; SUB1; UBE2L3; BNC2; ZNF32; NCOR2; ZFPM2; SF1; APEX1; ZFP36L2; KAT2B; SOX17; HIRA; ZNF232; CAMTA1; NCOA6; BATF; CIZ1; UBTF; BACH1; TRIM27; PLAGL2; HOXD11; PAX6; AGO2; COPS2; HMGXB4; ZIC1; PIR; RARB; HLX; CTCF; EN1; KLF9; TULP4; BRD3; CHD3; ENO1; FOXE1; ZNF84; TRAK1; TFCP2; HOXB7; TGIF2; TRIM29; SALL2; PMS1; ZIC3; EHMT2; REXO4; LIMD1; KAT6B; PHIP; SP3; POU5F1B; MED1; PPARGC1A; MZF1; CITED1; NKX2-2; KLF1; LITAF; HMGB1; RBBP4; PAXBP1; MTDH; PSMC3; PBX3; ZEB2; FUBP1; TFEB; KAT7; HMG20A; HIPK2; HIPK3; SUPT3H; HOXA11; ZNF239; REPIN1; BAZ1B; SMARCA1; HOXC4; BMI1; PCGF1; MMS19; CUX1; NR1D2; CTBP1; SUPT7L; BHLHE40; PITX2; WWTR1; ZNF512B; FOXF2; JAK2; TBL1X