Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID81461	Doxorubicin	GSE92742	HA1E	Human	24h	10.2uM	EID0407

Response Information :

Types	Number	Response transcription factors
Up-regulation	317	MEIS2; IRF6; ZNF415; RBFOX2; THRA; ZNF816; MED14; TCEA2; SOX17; JUP; ZFPM2; PRDM14; ATOH1; ACTL6B; ZNF154; ZNF117; RING1; AR; ZNF345; SPDEF; SOX2; FOXF2; CDIP1; RSF1; LIN28A; SOX5; ZNF180; E2F4; ZBTB20; ZNF667; NFIX; ZNF701; RAD21; ZIC3; FEZF2; CDX1; TCF21; ZNF835; NFATC3; ZBED2; CUX2; E4F1; NR0B1; SOX13; TFAP2A; ZNF91; ZNF573; HIPK2; ARL2BP; ERBB4; ZNF205; RFX1; ZNF682; KAT2B; CARF; ZNF235; ZNF43; ZNF85; HESX1; HEYL; ZNF254; ELK4; ZNF331; ZNF264; YEATS4; SOX3; ZNF467; ZNF215; ZNF423; ZFP2; MXI1; NCOA3; TRIB3; EHF; GBX1; ZNF665; SPI1; ING4; ID4; MEIS1; ZNF589; MYCL; ST18; ZNF528; AEBP1; PROP1; ZNF219; VENTX; NR5A1; BARX1; TULP3; CBX4; POU6F2; SOHLH2; SALL2; IKZF1; TAF11; SKI; CHD2; ZNF224; HSF4; ZNF140; ZNF562; HIF3A; WDR77; ZBTB44; CNBP; ZNF124; LHX3; HOXB1; SRY; CERS6; SOX18; TAL1; ZNF688; TP73; EP300; ZNF671; KDM5C; PEX14; HLX; FOXJ1; MED25; CDX4; PBX2; ZNF107; NR0B2; THRB; LZTR1; CEBPE; ZNF223; ZEB1; ZKSCAN4; ZNF74; SRCAP; ZNF250; ARNT2; ARID1A; MAML3; HOXD1; ATN1; HIPK1; PBX1; DCC; NR4A2; ZNF329; RARG; TAF1; ZNF232; ZBTB3; SUMO1; HSF1; SCAI; GATA1; CBFA2T3; TTF2; TRPS1; MED15; ZNF239; TDP2; TAF6L; SIX6; NHLH1; SOX21; NAB2; INSM1; CREBL2; CALCOCO1; REL; TBX2; ZNF500; PRDM1; NEUROD1; HDAC9; MECP2; KLF13; TBX5; PRRX1; SCRT1; NFE2L3; ID3; NEUROD2; ZBTB17; MEF2C; ZNF44; ZNF695; HOXB5; CREB1; OVOL2; E2F2; SMARCB1; HIRA; ZNF253; IRF8; SSBP3; GATA2; CREM; SUPT3H; CD3D; CBX7; KAT2A; L3MBTL1; TBX21; ZSCAN9; VGLL1; ATF5; EMX1; PHF1; POLR3C; RORA; EYA2; ZNF195; ZNF770; DBP; ZNF304; MYRF; ZNF273; SSBP2; SLC2A4RG; PRDM2; BCL11A; NKX2-2; PEG3; ZNF83; ZNF75D; GFI1; TGFB1; ZNF771; ZNF623; SNAI2; PIAS4; CNOT3; MECOM; ZNF551; PPARD; EHMT2; ZNF141; HMX1; TAF5L; TBX1; FOXH1; SUPT4H1; BAZ2A; PRDM10; CBFA2T2; ZFHX3; CIITA; CALR; ZNF611; VPS72; ZNF34; TCF3; WT1; NKX2-1; BNC1; MED12; VDR; ZNF10; HIC2; ZNF544; CEBPD; ZNF268; TCEA1; CIR1; ZNF606; IFI16; TFDP2; ZSCAN18; FOS; HMGA1; MYT1; STAT4; ZNF580; TAF1C; NR2C1; NCOA2; PKNOX2; NHLH2; THAP7; FOXF1; PHIP; E2F5; ZHX2; PAX6; ZNF711; NFATC4; SSX1; WNT4; HBP1; MDM2; DLX5; ZNF350; PRDM12; FOXA2; NR5A2; MZF1; FOXA1; FUBP1; CERS4; EPAS1; CSDE1; GON4L; CNOT2; NANOG; SHOX2; ZNF136; CAMTA2; KLF11; ESR1; PCGF3; DLX2; CCNH; ATF3; EMX2; ZNF654; OLIG2; NFE2
Down-regulation	389	FHL2; HOXA5; CCNA2; TRIM32; TBP; CENPF; HNRNPD; NRBF2; BRD8; NELFB; SUV39H1; EZH2; NUP62; FOXO3; SOX9; PHF20; EED; RNF4; SCAND1; FOXJ3; PAX8; NCOA4; MED6; EDF1; BCLAF1; ZNF672; BHLHE40; HDAC2; AATF; NR2F2; CTR9; BRPF1; UBE2I; RBM14; SMARCA5; NCOA6; TAF10; HOXA7; ZNF146; TSC22D2; REPIN1; PUF60; SFPQ; MED1; SAFB2; XBP1; KAT5; NRIP1; ZBTB24; SNW1; ID2; DPF2; MTF2; SMAD2; TCERG1; BAZ1A; SIX1; BRD3; SOX4; ATF1; PREB; TSC22D1; CHD1; FOSL1; DNMT3B; ZBTB1; WWC1; ABL1; SMARCE1; HOXC6; ELK1; CRK; RUNX1; NSD1; MLX; ATF7IP; ZNF410; TP53; CEBPZ; BANP; MYC; GABPB1; NCOR2; BASP1; UIMC1; DR1; BCL10; TTF1; SREBF1; KDM2A; USF2; ECD; MED27; RBBP4; NPM1; CREB3L1; KDM5A; CENPB; ING1; TRIM16; REST; WDHD1; BRCA1; REXO4; ZNF263; MAML1; YAF2; ZFP64; SETD2; TCF12; TBPL1; MED4; RAN; ETS2; LIMD1; ZBTB11; PIAS2; CASZ1; KAT7; CHAF1B; SIX2; FOXD1; PSPC1; HOXA10; ITGB3BP; BMI1; FOXC1; SERTAD2; NKX3-1; PCGF2; RREB1; MAGED1; KDM5B; CNOT1; CRY1; RNF14; ORC2; FOSL2; TFCP2L1; ELF5; DDX54; VGLL4; RARA; CCNC; PURA; ZNF443; BAZ2B; ZMIZ2; PATZ1; SMAD7; BCL6; AFF1; ZBTB18; MSL3; NRF1; ANKRD1; MGA; GTF2IRD1; LMCD1; RELB; ING3; ZNF282; ZNF292; ZNF143; FLNA; NEDD8; SMARCA2; ZNF189; PHF2; KLF2; RBM39; ING2; BTG1; MNT; ELF2; ZNF473; RBL1; ARID4A; TAF1D; HOXC10; SND1; CDK7; PRPF6; MAX; TRIM27; TBL1X; MED23; DNAJC1; ZBED1; BLM; THAP1; PCBD1; TFAM; SIAH2; ZZZ3; ZSCAN12; ASH2L; IKBKAP; TADA2A; SMAD3; ALX1; NPAT; HR; RNF111; ATF4; ERBB2; STAT5B; HSF2; VEZF1; PMF1; STAT1; CBX3; TMF1; USP22; HOXA11; HTATIP2; NR3C1; HSBP1; MITF; KLF12; ELK3; PHF8; ZNF212; IKZF5; RBBP7; KDM4A; CXXC1; SFMBT1; KAT8; NFKB1; TRIP4; SMARCA4; SP110; SAP30; RCOR1; RBPJ; ZNF267; SMARCC1; TEAD1; IRF7; SIM2; ELF1; BRIP1; MEF2A; JARID2; PLAGL2; ZNF302; SSRP1; SETD3; HMG20B; RB1; ZNF408; SP140; POLR2A; DEK; ZBTB25; ASXL1; NFE2L1; ATF6; HOXC13; HCFC2; ZNF783; ZSCAN5A; SNIP1; YBX1; SMARCD2; GATA3; RLF; CBFB; BATF3; ADNP; TLE1; MED24; ARID4B; KMT2A; HOXA1; DNAJC2; SMAD4; NFIL3; AIP; PRRX2; ARNTL2; NFYA; ADNP2; HLTF; HOXB7; NFYC; PQBP1; RNF6; MNAT1; NCOR1; ZBTB38; DRAP1; CCDC59; BCL3; JUNB; ZFHX4; HOXD10; HES1; UBE2B; RELA; MSC; SP3; ENO1; SAFB; TLE4; RNF138; DEAF1; NFKBIA; NFIB; YWHAB; PSIP1; KLF6; USP21; PRDM4; RUVBL2; PTTG1; HIVEP2; TRIP6; EGR3; PML; WHSC1; SMAD1; HMG20A; BCOR; EGR1; ZBTB40; SPEN; ERCC3; TSC22D4; MBD2; KAT6B; CHD9; TRIM29; SCMH1; SIRT7; WWTR1; PITX2; STAT3; RNF141; THRAP3; KDM5D; ZNF226; COPS2; BAZ1B; ZNF84; ZNF629; TAF5; E2F6; NAB1; BBX; PPRC1; ZEB2; CHD8; TFCP2; ZNF384; ELF3; HDAC1; NONO; BTAF1; TRIP11; RUNX3; NFYB; MAFF; ZNF217; MSX1; LPIN2; CCNE1; TRRAP; EGR2; RHOA; RYBP; RBBP5; RNF10; TRIM28; TULP4; APEX1; NFATC1; RFC1; SUB1; CARHSP1; ERG; TBL1XR1; HDAC6; TRAK1; RXRA; HMGB2; ZNF574; IRX5