Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID81440	Doxorubicin	GSE92742	HA1E	Human	24h	10.2uM	EID0405

Response Information :

Types	Number	Response transcription factors
Up-regulation	264	SOX17; ZNF415; SALL2; ZNF331; ZNF816; TWIST1; ZNF268; MYCL; TGFB1; ATOH1; ZNF667; HOXB1; ZNF701; ST18; ZNF467; SOX2; GBX1; LDB1; LHX3; ZNF688; LIN28A; PRDM14; CDIP1; RAX; ZNF573; NKX2-2; ZNF257; EVX1; INSR; L3MBTL1; ZNF154; SOHLH2; ZNF682; PHF1; ZNF205; HLX; HOXD1; CIR1; ZNF117; TFAP2A; RFX1; ZIC3; SOX18; KLF13; ZSCAN18; NOC2L; ZNF180; ZNF711; CERS6; HIF3A; JUP; ZNF223; HMGA1; CEBPE; NFATC3; KDM5C; E2F4; FOXJ1; THRB; PBX1; HSF4; RING1; ZNF562; FEZF2; CEBPD; CAMTA2; CNBP; PROP1; HOXA3; ZFHX2; ACTL6B; TSHZ2; BARX1; IRF6; SRCAP; ZNF264; THRA; SIX5; AR; CREBL2; ZNF75D; ZNF611; ZNF671; RSF1; PBXIP1; ZNF345; EHMT2; HES1; TCF3; MED12; CBFA2T3; HEYL; HSF1; IRF8; SPI1; SSBP3; TCEA2; HOXB5; HIPK2; NEUROD1; FOXA2; ZNF768; MEIS2; CUX2; TP73; WDR77; SHOX2; E4F1; SUPT3H; HAND2; ZNF254; WT1; VPS72; TAF6L; EP300; MAML3; CHD2; PRDM12; ZNF835; ZNF219; TDP2; NHLH2; PEG3; KAT2B; MYRF; ZNF423; ZNF141; BCL11A; VGLL1; ZKSCAN4; POU2F2; SOX3; HMX1; BAZ2A; HDAC9; VENTX; HOXD3; CRTC1; ZNF695; TEAD3; ZNF589; ZNF606; CBX7; ZNF654; MED25; NKX2-1; ZBTB44; ZNF771; FOXF1; CNOT3; DBP; ERBB4; ZNF224; SIRT2; ZNF124; HAND1; MECOM; SKI; ZFPM2; ING4; NCOA3; EMX1; ZNF500; ZNF43; CAPN15; TCEA1; RBFOX2; PPARD; ZNF350; PBX2; SRY; ZNF556; NHLH1; WNT4; CDX2; HBP1; NR2E1; ZNF91; CARF; ASH1L; CDX1; NFIX; SOX21; RARG; ZNF329; MYBBP1A; BRD4; INSM1; SUPT5H; ZNF665; ZNF512B; GATA2; RORC; DLX5; SIX3; PRDM1; ZNF93; ZNF358; ARL2BP; HMGN3; NFATC4; OVOL2; ARID3B; MED14; TBX1; HMBOX1; ZNF195; TAL1; ZNF225; TRPS1; FUBP1; FOS; HIC2; MAF; ZNF354A; E2F2; EHF; ZSCAN9; NFE2L3; ZNF544; ZNF232; VDR; ZNF135; MYCN; ATF5; MXD4; NR4A2; ZBTB16; ATN1; ZNF623; ZNF536; ZNF253; ISL1; KAT2A; SMARCC2; BNC1; SLC2A4RG; ZNF580; ARNT2; DAXX; PRRX1; GTF3A; MECP2; FOXF2; ZNF528; TAF9B; ZNF140; ZEB1; BNC2; CALCOCO1; SAP18; ESRRG; NFAT5; ZNF551; TCF21; SSBP2; SOX5; PNRC1; CALR; TULP3; MDM2; SOX11; MEOX2; HIRA
Down-regulation	389	CCNA2; MYC; XBP1; SNW1; SUV39H1; FOXO3; RBM14; NRIP1; CENPF; PATZ1; NUP62; EED; CRK; CDK7; FHL2; NFKBIA; TBP; TCF12; NRBF2; TRIM16; MED6; FOXJ3; EZH2; PHF20; USP22; CCDC59; PAX8; CEBPZ; CHAF1B; KAT5; PUF60; HOXC6; MLX; KLF10; BRCA1; KAT7; ELF1; CHD1; SETD2; ZNF672; TLE1; ZBTB11; NKX3-1; ING2; TMF1; ZNF146; HNRNPD; PHF2; TRIM32; ZFP64; SMARCA5; ADNP; REST; SNIP1; VEZF1; AATF; ZBTB24; BATF3; ZBTB1; BAZ1A; BRD8; BRD3; NCOA4; NCOA6; ZBTB25; VGLL4; ECD; MED1; ID2; ZNF410; MAX; HOXA7; PCGF2; HOXA5; BRPF1; BCLAF1; GABPB1; DPF2; RNF4; DNAJC2; SCAND1; RNF111; NFKB1; PSMC3IP; HDAC2; HOXA10; ANKRD1; RELB; SMARCA4; TSC22D2; KDM2A; ZNF292; ZMIZ2; ORC2; UBE2I; TCERG1; EDF1; ZZZ3; RBBP4; ING1; ATF1; HOXC10; NRF1; LIMD1; KDM5A; YAF2; DNMT3B; ADNP2; GATA3; SMAD4; RB1; SMAD2; SMARCE1; PIAS2; SERTAD2; ELF5; SAFB2; ZNF408; BANP; KMT2A; BAZ1B; BTG1; CBFB; NR2F6; TBPL1; CASZ1; RELA; ZNF143; NR3C1; HIVEP2; SIAH2; RBL1; ELK1; FOSL1; PTTG1; ZNF282; IKZF5; NELFB; SFPQ; SFMBT1; MAFF; NR2F2; NFYC; MNAT1; TRIP4; IKBKAP; FOXD1; KLF12; PIR; TAF9; PHF8; KDM5B; FOXC1; RARA; DEAF1; ZNF263; CTR9; ZNF473; FOSL2; RCOR1; KAT8; FLNA; ARID4A; MAML1; PREB; WDHD1; SMAD7; HMGB2; HMG20A; CXXC1; CRY1; BLM; SOX9; SMAD1; RBM39; WWC1; ZNF337; ASH2L; BHLHE40; THAP1; TAF1D; HOXD10; RUNX1; CENPB; UBP1; ING3; IRF2; SIM2; SMARCA2; ABL1; KDM5D; PPRC1; CTCF; TADA2A; NSD1; SIX2; RREB1; SREBF1; JUNB; PURA; KLF2; HOXA11; BCL10; DDX54; MGA; ZBED1; ZSCAN12; GMEB2; TAF5; TTF1; UIMC1; RBBP7; MSL3; NPAT; RNF138; IRF7; DNAJC1; MED23; JARID2; MED27; TBL1XR1; COPS2; PKNOX1; PSPC1; TERF2; MTF2; WWTR1; ATF4; ZBTB14; BMI1; ELF3; CITED1; POLR2A; DR1; GTF2IRD1; REPIN1; E2F6; ASXL1; ITGB3BP; FOXO1; HOXD9; ZNF384; ZNF217; PAX9; SAP30; STAT6; SIX1; UBE3A; POU4F1; ZNF189; AFF4; SPEN; RAN; BTAF1; ARID4B; ATF7IP; TBL1X; REXO4; ZNF394; PRDM4; MED7; STAT1; BAZ2B; TAF4; SMAD3; RBBP5; ARNTL; WHSC1; AFF1; TRIM27; ELF2; ZNF16; AGO2; ERCC3; TADA3; RBPJ; CBX5; BCOR; ZBTB18; ZHX2; ZNF629; CREB3L1; AIP; MTF1; SALL1; TCFL5; PLAGL2; ZBTB40; MED4; MLXIP; TAF10; NFE2L1; EGR2; PRPF6; ZNF267; TRRAP; SMARCC1; NFYA; HSF2; RFC1; GMNN; HDAC1; PQBP1; CNOT1; DDX17; EP400; ZNF212; ZNF148; TFAM; GABPA; SIRT7; XRCC6; RNF14; PMS1; HCFC2; NAB1; USF2; CEBPB; LMCD1; NEDD8; SP3; PSIP1; MEF2A; CSDC2; MYNN; ZNF7; HMG20B; NCOR2; CBX3; ZHX3; KLF6; NPAS2; CTBP2; BIRC2; STAT5B; MED13; ZNF576; DEK; ZBTB38; ZNF692; MBD2; MED21; MTDH; DDIT3; MLLT10; TRIP11; MSC; DMTF1; ZNF266; ZNF202; HMGB1; APEX1; RRN3; ZMIZ1; HOXB7; HOXD11; TEAD4; PCGF1; RLF; NFIL3; TOPORS; NFX1; CTBP1; NKRF; HMGXB4; PPARGC1A; LPIN2; NPM1; TP53; CIZ1; ALX1; CHD7; WWP1; ZNF24; SSRP1; UBE2L3; BRIP1; TGIF1; SOX10; CEBPG; TRIP6; SATB2; SOX4; ZNF443; RXRA; KAT6A; HSBP1; E2F8; CHD8