Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID81405	Securinine	GSE92742	CD34	Human	24h	10uM	EID0227

Response Information :

Types	Number	Response transcription factors
Up-regulation	280	SMAD3; ZFPM2; ZNF74; TULP3; RBFOX2; ETS1; BARX1; SOX13; RRN3; GLI2; ZNF329; ARL2BP; TCF7L1; TLE2; ZNF667; ZNF117; ZNF345; ZSCAN18; ZNF124; KLF5; SOHLH2; CDIP1; ACTL6A; ZNF12; NR1H2; PBX1; NFAT5; ILF2; CITED1; TCF4; TDP2; YEATS4; TEAD3; ZKSCAN8; SPDEF; CDK8; ZNF34; MEIS2; ZBTB7A; TXNIP; PIAS4; SCAI; TAF11; TGIF1; AR; GMNN; NR0B1; GRIP1; C1D; ZNF154; PRDM2; ZBTB20; MED21; ZNF132; SOX5; TEAD4; RARG; NFATC4; HIC2; JUP; E4F1; CITED2; TERF1; MAGED1; FOXO1; RXRG; PRDM1; NR5A2; POLR3C; ZNF675; HINFP; MYT1; KLF10; LHX3; SOX11; RSF1; SP2; ZSCAN9; TBX5; NEUROD1; ZNF135; ZNF512B; BACH2; ZNF239; TAF1A; ZFP36L1; PCGF1; ZNF665; CRY1; ACTL6B; FOXE1; ING4; TCF3; TBX21; ZIC3; ZNF354A; MYT1L; ZNF415; SALL2; HOXA3; MNT; CBX4; ST18; AFF4; ID4; MYBL1; ZNF623; SMARCA1; AGO2; ZNF529; PRDM14; ZNF223; PEG3; GATA1; TFAP2A; NFE2L3; HSF4; TAF9; TCF21; IKZF3; HIRA; HMGXB4; ZNF682; BACH1; MDM2; DRAP1; ZNF576; RORA; GFI1B; STAT4; ATF2; ZNF141; RBPMS; TSC22D1; JUN; DDIT3; KAT2B; CCNT1; PEX14; DCC; VGLL1; VPS72; RNF2; ZNF573; KLF11; PCGF3; TCF7L2; GTF2I; KLF3; MDM4; TFAM; ZNF254; CREB3L2; PQBP1; ZKSCAN5; NKX2-2; CSDC2; TAF6; ZNF43; KLF1; DLX5; ELK4; ZNF331; NLK; NR2F1; SUPT3H; NR2F6; PAWR; ZNF652; RAD21; MYCBP; RLF; ZNF224; HOXA1; SMARCD3; HOXB2; TAF4; HES1; ZNF226; ZNF8; CAMTA2; HBP1; PGR; HOXD1; TGFB1I1; ZNF143; IRF2; FOSL1; ZNF556; ZNF22; CBX7; ZEB1; ZKSCAN7; NR1H3; ZNF711; SRCAP; CAPN15; ZNF532; BNC2; ZFP2; ZNF506; OSR2; ZNF562; SKIL; ZNF571; CNOT2; ZNF232; ZNF91; SSBP2; ZBTB38; YAP1; TTF2; HDAC9; PDLIM1; ZNF264; ADRB2; CALCOCO1; TEAD1; ANKRD1; ZBED2; ZHX2; E2F5; CRYM; ZNF180; ZNF273; HEY2; CBFA2T3; ZNF44; EPAS1; PTRF; IRF9; SPIB; WT1; ZNF165; TCEA2; CDYL; MED13; INSM1; FOXA1; SSX1; MKL2; WWTR1; NR1D2; SOX2; IRF6; BLZF1; HOXA11; EGR2; SKI; TCFL5; ZNF606; ZNF611; ZNF148; MAFF; ZNF544; HHEX; NCOA2; TWIST1; GRHL2; TRPS1; PBXIP1; ZBTB16; ZNF83; CUX2; CREB1; FOXG1; BTG1; SNAI2; ID1; THAP10; ZNF85; NANOG; HOXA10; ZNF160; GATA6; TOB1; MITF; PLAGL1; ZNF589; ARID4B
Down-regulation	334	NCOR2; RUNX3; CEBPA; NFKBIA; PUF60; RFX5; MTA1; CENPF; ZNF672; NCOA4; CBFB; CXXC1; HLX; TAF1D; TAF10; IRF5; MBD2; BRCA1; ETS2; SETD3; RBM39; USF2; TSC22D3; STAT6; PA2G4; SSRP1; TP53; ZBED1; KDM2A; TRIM28; APEX1; FLNA; CENPB; AATF; ARID4A; MGA; ZBTB40; SPI1; PPARGC1A; ZNF281; ELF1; KDM4A; ASH2L; SREBF1; ENO1; STAT5A; ZNF24; SPEN; MXI1; BRD7; MLX; BATF3; LDB1; KAT2A; UIMC1; CIITA; NCOA6; FOXO4; PURA; KLF6; ZMIZ2; MKL1; SMARCC1; ZNF140; CNBP; PRPF6; ARID5A; HMGA1; ATF6; SFMBT1; SMAD2; MNDA; BTAF1; SRF; CSDE1; MED6; HIVEP2; MAFG; BRPF1; NFKB1; SREBF2; SETD2; TFCP2L1; BAZ1A; ZNF467; MYB; SMARCD2; PBRM1; HCFC1; FOSB; NONO; SFPQ; ESRRA; HNRNPD; NFYC; NR1I2; MXD3; HDGF; EP400; BRD8; NPM1; HIVEP3; ERCC2; SOX4; HEY1; MTF1; BLM; ATF4; CHAF1B; BTF3; PIAS2; MAZ; ZNF629; NSD1; PRMT2; SND1; RUNX1; ARNT; NKRF; EMX2; SIM2; YBX1; NELFB; ZNF384; MMS19; MYBL2; PHF2; ZNF337; HLTF; DDX54; BRF2; CIZ1; KLF12; CHD3; VDR; MED1; BAZ1B; SMARCE1; EDF1; TFDP1; PATZ1; MTDH; SNW1; USP16; DNAJC1; TCERG1; SF1; PPRC1; GFI1; NEDD8; MED24; GATA2; RBBP7; KAT5; ERBB2; YWHAB; CNOT1; BCLAF1; ZBTB14; ORC2; MEF2A; ZBTB39; REXO4; TOX4; RELB; HMGXB3; PHOX2B; RUVBL1; PTTG1; KDM5A; HDAC7; AFF1; NFKBIB; POU3F2; PARP1; RBPJ; BMI1; NR3C1; PSMD9; KMT2A; ZNF212; ID3; ZNF84; ATF7IP; ZBTB48; GTF3A; BRD3; RUVBL2; SMARCA2; HDAC4; SMARCA5; CRK; SP140L; ZHX3; CARM1; TCF7; BIRC2; HDAC1; HDAC3; LYL1; HDAC6; HAND1; MTF2; ELK1; PCGF2; FOXJ1; XBP1; CHD7; NAB1; ZNF710; ZFHX4; IRF8; ZNF536; TRAK1; RAN; RBM14; HIPK1; RNF138; HTATIP2; ZNF516; DEAF1; TCF25; MED23; AIP; GABPB1; ZNF768; TTF1; SP100; RNF10; PIAS1; DAXX; UBE2B; MLXIP; CDK9; DLX2; TBP; ECD; ZBTB11; MSX1; ZNF266; ELK3; MEIS1; NCOA1; SSBP3; WHSC1; NFE2; ZNF267; PAX8; HR; REST; CTR9; IFI16; MAFB; BAZ2B; TRIP6; POLR2A; MSC; TGFB1; ALX1; POU4F1; HSF1; TCF12; KLF7; SP140; KLF13; CDK2; NFX1; KAT6B; RFXANK; WWC1; GATA4; NFYB; SMARCB1; IL16; HOXB7; HOXC4; TSC22D2; MECOM; STAT3; BASP1; ID2; PSMC3IP; CTNNB1; TGIF2; ZKSCAN1; SMAD6; CREG1; SCAND1; FOXD1; ZNF394; TRIM32; HOXB6; SMARCA4; MYCL; SAP30; ZBTB1; TFEB; CALR; CEBPG; TRIM29; RXRA; FOS; STAT5B; BHLHE41; ETV5; AHR; FOXN3; CEBPB; SATB2; PSIP1; UBE2I; ASCL1; BATF; SOX9; ERG; TFEC; PFDN5; CREB3L1; TLE4; NR2F2; KLF2; TADA3; ARID5B; YBX3; KDM5D; BCL11A; TCEA1; TOX3; MYCN; TRIM22; ZBTB18; MAF; HOXC6; EGR3