Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID81377	Securinine	GSE92742	CD34	Human	24h	10uM	EID0226

Response Information :

Types	Number	Response transcription factors
Up-regulation	219	ZNF239; IRF9; TAF11; NR4A1; HOXD1; DRAP1; ZNF426; ZNF652; ZNF329; MEIS2; VPS72; ZNF34; RRN3; ZNF74; SCAI; GTF2I; ZNF85; ZNF22; ACTL6B; ZNF606; TDP2; ZNF350; GATA6; MED21; ZNF154; CDC5L; ZKSCAN8; PLAGL1; TAF5L; ZFP2; TCEA2; GMNN; CBFA2T3; ZNF136; HOXA5; POLR3C; KAT2B; BNC1; RSF1; ING4; RBL2; SUMO1; C1D; ZNF124; ZNF711; ARL2BP; ZNF160; ZNF571; NR2C1; ZNF675; MYT1; CREB5; HMGXB4; HIC2; ZNF611; ACTL6A; ZNF721; ZNF345; ZNF257; CRYM; ZNF8; CARF; SNIP1; ZNF264; NR4A3; YEATS4; NEUROD1; RLF; TCF7L1; HDAC9; ZNF135; TSC22D1; ZNF223; ADRB2; PRDM10; E2F5; CTBP1; ZNF623; MYT1L; TFAM; GLI2; ELK4; HCFC2; SOX13; ZNF44; TEAD3; HMGB2; ZBED2; ZNF669; THAP10; CREB3L2; ZNF117; BLZF1; FHL5; ZNF432; ZNF529; ZFP69B; TAF9B; SSX1; ZNF304; ZNF14; ZNF180; JUN; ZNF354A; ZNF32; DACH1; SOX11; TXNIP; TEAD1; SP2; ZNF512B; CLOCK; MED17; HIRA; TULP3; RBFOX2; GFI1B; MEOX1; NKX3-1; ING2; CUX1; MKL2; THAP7; ZFP36L1; SOX15; ZNF141; HLF; ZNF226; TFAP2A; ZNF562; ZNF544; CDK8; ZNF91; RAD21; INSM1; ZNF12; TCF4; ZNF268; NHLH2; ZNF43; YAP1; TGFB1I1; AR; SMAD7; UBE2B; MYC; ZBTB38; SUV39H1; ZNF148; ZNF665; CITED1; ZNF140; CBX7; ARID5B; FOXE1; SOX9; ZBTB20; SMAD5; FOXF2; CCNT1; SMARCC2; TOB1; ZNF274; GTF2IRD1; ZFPM2; PEX14; NR1H2; SPDEF; ZNF143; NFAT5; TEAD4; IRF6; NR3C2; ZMYM2; TCF21; ZHX2; PBX1; NR0B1; ING3; MNT; SKI; TAF7; CBX3; PAX6; TRPS1; ZNF573; SIX1; IRF2; CREB1; WT1; SSBP2; TFEC; SNAI2; PDLIM1; RNF6; CREBL2; NR1D2; EYA1; TRIB3; PTRF; ZNF331; HOXA10; NFE2L3; ELF5; MYBL1; ST18; TOX; ZNF165; RYBP; RBPMS; NR2F1; RERE; PAWR; EN1; IRX5; TWIST1; KLF5; LEF1; ZSCAN18
Down-regulation	268	CEBPA; NFKBIA; SPI1; ELF1; TRAK1; ENO1; NCOR2; USF2; MTDH; PARP1; EP400; MBD2; ATF6; TFDP1; PUF60; HOXB7; ASH2L; GFI1; AATF; FLNA; RNF10; ELK1; BLM; KAT2A; SMARCC1; EDF1; PA2G4; MKL1; ZBTB48; ERCC2; SF1; TRIM28; MZF1; ZNF629; PMS1; KDM2A; FUBP1; ZNF516; SOX4; TAF10; ZNF281; SREBF1; NR2F6; BRF2; BATF; ZNF672; PURA; CBFB; RUNX1; PRMT2; CIITA; MTA1; SND1; SSRP1; IRF1; BRD3; MSX1; BASP1; CXXC1; RUNX3; NFE2L1; DEAF1; MGA; MAX; BRCA1; ATF4; CENPB; MXD3; BCLAF1; ZNF552; MYB; KMT5A; ASCL1; RFX5; RBM39; CDK9; TFCP2L1; TAF1D; MAFG; LYL1; CIZ1; THRAP3; ZMIZ1; BIRC2; RBM14; SETD2; HOXB6; KMT2A; TCEA1; ZBTB1; NELFB; EYA2; ZFHX4; KLF12; MLXIP; IRF5; IL16; CSDE1; CHAF1B; UBE2I; CARM1; COPS2; HLX; VDR; ATF5; BRD7; TGFB1; ESR1; ZMIZ2; MBD3; WHSC1; RFX2; POU4F1; NUP62; ZNF384; DNAJC1; ESRRA; ZBED1; UIMC1; BTAF1; HR; PREB; NFKB1; HIPK1; STAT3; BRD8; POU2F2; AFF1; RUVBL2; KDM4A; BATF3; DMTF1; POU5F1B; SREBF2; FOXO4; SMARCD2; HOXC6; PCGF2; PML; NCOA4; CARHSP1; RBBP8; MEF2A; SP140L; ETS2; USP16; ZBTB40; ZNF467; HHEX; TERF2; RELB; MAFB; PPARGC1A; CHD3; LIMD1; NFE2; TSC22D3; CALR; TCF25; HOXB5; GABPB1; BAZ1A; SCAND1; NFX1; POLR2A; ZNF282; BRPF1; RFXANK; XBP1; STAT6; TP53; RXRA; PSMC3IP; DLX2; SP140; MTA2; CREB3L1; MED1; ERF; MYBL2; GLI3; INSR; MEIS1; AEBP1; NCOA1; HMGA1; TOX3; ARID3A; RUVBL1; POU3F2; MSC; KLF13; MXD4; RBBP7; ID2; ARRB1; SP100; SMARCA2; TFEB; SIN3B; MAZ; MLX; SATB2; MMS19; CNBP; BAZ2B; CNOT1; SMAD2; FOXN3; SMARCE1; MXI1; SETD3; RCOR1; SUPT6H; FOSL2; HLTF; ZNF146; JUNB; ZNF580; PAXBP1; NAB1; BTG1; NR1I2; SSBP3; CHD7; TCFL5; TRIM27; HNRNPD; STAT5A; ZNF768; SMARCB1; EMX2; KLF6; SP110; CENPF; DNMT3B; HSF1; ECD; PBRM1; YBX1; COPS5; STAT5B; TRIM16; STAT1; SIAH2; IRF4; RBBP4; PSMC3; ZEB2; CTBP2; MAF; CTR9; CNOT3; DAXX; FOXO1; CEBPB; PRPF6; PBX3; ID3; TCF12; KAT6B; ELK3; POU2AF1; YBX3; KDM5D; TRIM22; KDM5A; PAX8