Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID81354	Securinine	GSE92742	CD34	Human	6h	10uM	EID0230

Response Information :

Types	Number	Response transcription factors
Up-regulation	97	NR1H2; PMF1; ZNF133; MED24; ZNF34; TBX19; HIC2; PBXIP1; JUNB; PAX6; TADA3; CDK7; HIRA; PCBD1; SSX1; RBFOX2; RHOA; ZNF394; OSR2; ZNF223; YAP1; NFIL3; SRCAP; SOX11; EZH2; UBE2L3; TEAD4; CREG1; ZNF571; MEIS2; RBPMS; HMG20B; SIX6; PTTG1; DBP; IKBKAP; PCGF1; ZNF580; NFYA; ZNF337; TAF6; CDK8; CITED2; BCL3; GATA6; FOXA2; HDAC5; SMAD5; TGFB1I1; HDGF; VPS72; TRPS1; RERE; CERS4; ATF4; PCGF2; SND1; EMX2; NR2F1; ZNF232; ZNF711; NFE2L3; MITF; SUMO1; GTF2A2; ACTL6A; TULP3; PBX1; SMAD7; TCEA2; FOXL2; RXRA; DLX5; PIR; GRHL2; JUND; BTG1; TRIP6; ARNTL2; ARID1A; KDM5D; KLF9; LITAF; SSBP3; WWTR1; SMAD1; MECOM; MNDA; TRIB3; MSX1; NKX3-1; YBX3; CREB1; ERBB4; TXNIP; PPARD; PDLIM1
Down-regulation	114	SATB1; ATF5; MTF2; TFDP1; RB1; USP22; TOB1; E2F3; SOX4; CBFB; CCNH; TP53; AGO2; RNF4; MXD4; MAFG; ELF1; BRCA1; SMARCC1; ZNF93; CHD4; KLF3; CTBP2; PQBP1; PFDN5; RFX5; ATF1; BATF; ELK3; HOXC4; STAT3; WHSC1; AHR; TSC22D2; MEOX1; ZSCAN18; TGIF2; HIPK1; PBX3; TRIM29; TAF1D; UBE2B; ZNF721; TERF2; C1QBP; BAZ1A; LYL1; KLF2; ERG; CHD1; TRIM33; FOXJ3; CBX5; ENY2; GTF3A; CNBP; CREBZF; RBBP4; TBPL1; EP400; ZBTB18; ZBTB16; NFIB; ZNF281; HSBP1; ZFHX4; SMARCA5; ZNF160; MTDH; MYB; BBX; HOXC6; VDR; NR1I2; NPAS2; ARID4A; SP110; DNAJC1; KMT2A; TBL1XR1; ZNF593; SFPQ; TCEB2; MAFB; NPAT; YBX1; NFATC1; INSR; AFF1; FUBP1; SIM2; NR2F2; DACH1; HMGN3; PHIP; ZEB2; DAXX; SMARCA2; HHEX; TRIM22; CREM; RUNX3; SAP30; ZNF423; BTAF1; ID1; BAZ2B; BIRC2; HOXD1; BHLHE41; ZNF91; ESR1; HEY1; TCFL5