Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID81308	Securinine	GSE92742	CD34	Human	6h	0.37037uM	EID0228

Response Information :

Types	Number	Response transcription factors
Up-regulation	134	SOX10; RELB; ELF5; SP140; NFATC3; SMAD4; C1QBP; PIAS1; EP300; SPIB; PAX5; SF1; ZFY; KLF5; SREBF2; ZHX2; ZBTB1; ZNF532; TAF7; TAF10; ZNF580; URI1; ZNF274; PPRC1; RBBP8; CEBPG; ZNF202; ZNF24; TRIM29; TBL1XR1; NRBF2; ERBB2; KMT2A; RNF138; PIAS2; JUNB; ZNF721; POU2F1; FOXD1; E2F5; BTG1; IRX5; NR1H3; HLTF; GATA6; USP16; CNBP; KDM5D; HEY2; PRKDC; DDX17; RBBP4; NR1D2; TCF7L2; MBD4; NFKBIA; ZNF3; MBD2; SSX1; GABPA; TOPORS; CUX1; YEATS4; NR1I2; ADNP; IFI16; BCLAF1; PITX1; CREBZF; EP400; TFEB; SMAD2; ZMYND8; MYBL1; POU4F1; NFE2L3; MLLT10; SMAD5; AATF; ING2; LEF1; EHF; ADRB2; KLF6; FOXM1; ZNF226; CITED1; TERF2; MLXIP; IRF2; SMAD7; ZNF281; KDM2A; ZNF654; GRHL2; EDF1; TGFB1I1; NKX3-1; TFCP2; FOXO1; ING1; RBL2; FLNA; ADNP2; ZBTB14; SMARCA2; PDLIM1; CTR9; TRIM22; HTATIP2; FOXN3; FLI1; SAP30; BHLHE41; TP63; JAK2; MEOX2; ID2; SNAI2; ZBTB16; HOXB7; CRY1; STAT1; KLF13; ZNF589; PIR; HSF2; CREB1; KAT7; HOXC6; MNDA; HOXB6; RFX5; ZEB2
Down-regulation	117	GATA2; ZMYM2; PHF1; ESR1; ZNF83; HIPK1; PCGF1; ZNF85; ATF2; ZNF43; CBFA2T2; RYBP; THAP4; WHSC1; ZNF248; CNOT6; ZNF606; CDK8; RUNX1; TLE1; PHF20; C1D; ZKSCAN4; ZNF468; CDYL; ELF3; SMARCD3; NLK; SHOX2; TSHZ2; ZNF544; GTF2I; MAZ; EGR3; RFXANK; ZNF331; ZSCAN9; HOXD1; GATA3; HMGB3; NFE2; RBFOX2; HOXD3; TAF4; NPAS2; SOX9; TFAP2C; ZNF552; MED13; HIC2; TRIM24; NFE2L2; ZNF250; ZNF253; CRYM; PROX1; TGIF2; ZEB1; ZFPM2; TCF25; TRPS1; ZNF189; E2F3; ZBTB38; AEBP1; BAZ2B; GTF2IRD1; RREB1; ZNF415; SRCAP; TAL1; SCAND1; JUND; YBX3; ELF4; CHD9; MED20; BATF3; AHR; DACH1; ZBTB20; MEIS1; NAB1; SALL2; PBX1; MAF; ENO1; TWIST1; TULP3; PBX3; CCNC; NR4A2; SMARCB1; ERG; HEY1; PPARD; CUX2; HOXA5; SIAH2; JARID2; TEAD3; NR2C1; TFAP2A; SUPT3H; MYB; BASP1; WWC1; MECOM; ZNF423; NFATC4; ABL1; GLI2; JUN; PEG3; SOX2; ZNF586; SPDEF