Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID81270 Pyrvinium GSE92742 NPC Human 6h 10uM EID0485
Types Number Response transcription factors
Up-regulation 105 RELB; KLF9; HIVEP1; ZNF274; DNAJC2; FOS; ZNF140; TP63; KLF7; EGR1; JUNB; ZNF160; ARID5B; ATF3; CEBPG; ARID5A; ZNF394; PLAGL1; GMEB2; NFE2L2; L3MBTL1; NR4A1; MECP2; ZNF268; HBP1; BHLHE41; JUN; NFKBIA; GMNN; MED13; MNT; HMGB2; ZFPM2; HOXA5; JUP; CREB1; BNC2; ZNF12; BTG1; FOSL1; TULP3; SNAI2; TOX; ZBTB38; BRD4; TLE2; PLAGL2; ARL2BP; KLF3; DDIT3; HIC2; TRIP6; TDP2; NFE2L3; FOSL2; SHOX2; ZNF331; NR4A3; XBP1; ZNF623; ZNF267; MEIS2; TRPS1; WWP1; UBE2B; TRRAP; CEBPB; ZEB2; ZNF165; POU4F1; CREM; HOXB13; TFAP2C; AHR; TFAP2A; HOXD1; DMTF1; ATF2; EGR3; NR1D2; RBPMS; ERBB4; GATA6; KLF5; TRIM22; RAD21; WWC1; ETS1; TRIM29; FOSB; CREBL2; RBBP8; FOXF1; SATB2; CRY1; NR4A2; WT1; ZBED2; MYBL1; SPDEF; USP22; IFI16; ID4; ZBTB16; TRIB3
Down-regulation 70 HES1; TLE1; ABL1; SMARCD2; WDR77; ELK3; NFKBIB; SOX4; MYCN; CHAF1B; SP110; ELK1; NEDD8; ASCL1; ZMYM2; PROX1; RBBP7; DPF2; SMAD7; MAZ; HMGB3; BRD3; HIPK3; GTF2I; PSPC1; HOXC6; HOXC10; LIMD1; ORC2; SMAD2; RBPJ; RBM14; TBL1XR1; CCNE1; E2F2; STAT5A; ZNF226; HEY1; HNRNPD; DBP; ID3; FLNA; NFE2; TP53; MAFB; ENO1; FOXD1; VGLL4; MYCBP; FOXJ3; RBBP4; PIR; CTNNB1; RXRA; CTR9; MNAT1; EYA2; FOXC1; TSC22D1; LEF1; TCF7L1; BRCA1; NR2F2; MED24; SALL1; TBL1X; SF1; ELF1; MAGED1; PURA