Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID81266 Plumbagin GSE92742 NPC Human 6h 10uM EID0485
Types Number Response transcription factors
Up-regulation 130 IKZF1; KLF9; FOXE1; ZNF83; MED21; NFE2L2; HOXA4; BANP; ZNF816; RBFOX2; ZNF350; SOX17; ZNF415; CBFA2T2; JUP; MED25; OVOL2; CNOT3; HSF1; ZNF331; ZNF250; RING1; NR1H2; TBX21; TULP3; TBX3; IRF9; JUNB; HOXA5; PNRC1; CEBPD; ZNF239; IRF6; HOXD1; SOHLH2; ING4; ZFHX3; KLF6; HOXD3; IRF3; PDLIM1; PBXIP1; HLX; ST18; ZNF444; TFDP2; LZTR1; NR1H4; MECOM; ZNF544; ZNF34; TFAP2A; ZNF623; ZNF91; FOXF2; ELF3; EHF; BHLHE41; NR4A3; TOX; PSMC3; DDIT3; JUN; SPDEF; GMNN; SUPT3H; RBM39; TCF21; ZNF232; TCEA2; PAWR; AR; RBPMS; ZNF165; RAD21; PRDM14; BNC1; MEIS2; COPS5; BNC2; CREB1; PEX14; BARX1; ZFPM2; BCL11A; AEBP1; HBP1; YEATS4; KLF4; TRPS1; TGFB1I1; GATA6; MYBL1; HOXB5; PEG3; CBFA2T3; E4F1; EPAS1; CNOT2; ETS1; POLR3C; SOX13; CREM; PRRX1; IRF1; IFI16; TEAD4; IRF8; WT1; MYCL; NR4A2; KLF5; ZSCAN18; CCNH; FOXF1; ZBTB20; HOXB2; FOXG1; CDIP1; ZBED2; DACH1; NR0B1; CREBL2; PHIP; SNAI2; MNDA; TRIB3; POU2AF1; ZIC1; ESR1
Down-regulation 245 ZMYM2; KAT6A; CCNA2; HMG20A; SOX4; MYCN; FOXO3; FOXJ3; GABPB1; E2F3; DLX2; GATAD2A; SOX2; CRK; RNF111; KDM4A; DDX5; TBP; ABL1; ZBED4; PCGF2; ELK1; SUZ12; SMARCC1; ZNF24; ETV5; HSF2; CARHSP1; ELK3; STAT3; BLM; SP3; ZBTB1; ZNF143; NRIP1; CBX5; MED6; HMGA2; CHD7; MED23; MED4; ZBTB24; BRIP1; RHOA; ZBTB39; BCOR; ARID3A; VEZF1; ZNF672; TBL1XR1; TCERG1; ADNP2; ORC2; BRPF1; SMARCA5; HNRNPD; EN2; CREBZF; CCNC; CHD1; LPIN2; FOXN3; TCF4; RFX5; NFYC; SERTAD2; ZEB2; PSPC1; CDYL; MED1; NFATC1; ASCL1; BRD3; ZNF629; ZNF45; PBRM1; RFX7; MED13; SMARCD1; NUP62; NR2F2; ZNF124; EP400; SMAD2; SMAD5; SOX9; PATZ1; NRBF2; RNF4; TP53; NONO; CCNE1; NCOA1; AATF; UBE2I; SMAD7; YBX1; RBBP5; KDM2A; BAZ1B; RERE; ZNF764; GLI2; MGA; BMI1; SFPQ; ZNF146; SREBF1; ZNF189; ETV4; HOXC10; CDK8; ZNF212; CBFB; POU2F1; GTF2IRD1; URI1; HOXC6; ATF7IP; ZNF84; RNF6; RUNX1; EGR3; TCF12; BCLAF1; KDM5A; UBP1; NFAT5; FUBP1; TBPL1; KAT7; DNMT3B; BTAF1; ZZZ3; PLAGL2; TRRAP; E2F6; UIMC1; KMT2A; NAB1; CTR9; TGIF2; ZKSCAN1; NEDD8; YWHAB; MEF2A; ADNP; SNIP1; RBBP4; MAFG; SMAD4; RCOR1; ZNF516; RREB1; PROX1; SMARCE1; JARID2; BRD8; NFKBIA; USF2; AFF1; BAZ2B; PURA; MAX; CREB3L2; FLNA; MKL2; CITED2; TLE1; ZNF3; CREB5; PHF2; BAZ1A; SIX1; TOX3; CHD9; ZNF443; NCOA4; SP2; ENO1; MAGED1; PCGF3; CUX1; SETD2; HDAC4; SUB1; ZEB1; PHF20; NCOA2; RBBP7; POLR2A; REST; PREB; REPIN1; CBX6; PHF8; TLE4; LIMD1; HMGB3; OLIG2; BRCA1; ZNF529; RXRA; TOB1; SETD3; TSC22D1; TTF1; ETV1; RBM14; ZBTB18; PSIP1; BBX; ID3; MYCBP; TBL1X; USP22; TGIF1; NFIB; ING3; TSC22D2; HIVEP2; ZNF217; BACH1; TCF7; MAF; TRIM32; ID4; WWC1; EDF1; HLTF; BATF3; ZNF131; MAFB; FOXC1; ELF1; BASP1; MSX1; ARID4B; SF1; SUV39H1; SATB2; CRY1; ID2; XBP1; LEF1