Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID81259 Oxamflatin GSE92742 NPC Human 6h 10uM EID0485
Types Number Response transcription factors
Up-regulation 99 FOS; EGR1; CREG1; FOXO4; CDK7; JUNB; YWHAB; SMARCD3; PPARD; SPIB; ZNF593; CTR9; IRF7; FOSB; UBE2B; ATF3; TBPL1; TCFL5; PHF1; ZNF654; TOB1; DNAJC1; BCL3; LYL1; POU2F2; SP110; NR4A2; FOSL1; TCF15; EGR3; SP100; NR4A1; KLF2; DLX2; NR3C2; CITED2; AHR; STAT1; BCL10; ZNF394; STAT3; MEF2C; MXI1; RBBP5; AFF1; KDM5C; ITGB3BP; SND1; BRD2; SMARCA2; NRBF2; SETD3; BRD4; BBX; TFAM; SIX1; MAFG; PRKDC; MAFF; PTTG1; HMG20B; MLXIP; KDM5A; IRF1; MYCBP; NEDD8; LHX6; TSC22D4; NR4A3; TCF7; CCNE1; DDIT3; CRK; NFAT5; JUN; CHD1; CD3D; ZNF331; NCOA3; FOXJ1; HOXD1; PURA; KLF5; HLTF; ZNF281; WT1; BHLHE41; EDF1; FOXC1; HIVEP2; PHF8; LOXL2; MNAT1; HMGA1; ARID4B; HOXC6; HHEX; NR2F2; CDK2
Down-regulation 155 ATF5; ZMYM2; ZNF22; ZNF227; SOHLH2; ERBB2; SMARCB1; ZBED1; ZNF83; ZNF43; CTBP1; NSD1; MYCN; CARHSP1; KAT2B; NR2F6; NCOR1; GTF2I; DDX17; ATN1; PMF1; ZNF140; GABPB1; ABL1; SMARCA4; NEUROD1; FOXM1; BTG1; RREB1; GLI2; CTCF; ZNF282; SCMH1; ARNTL2; SOX2; ZHX2; ZNF532; TCERG1; PCGF3; SETDB1; SMARCE1; ZNF606; SP3; BPTF; CUX2; ZBED4; ZFY; APEX1; SALL2; NRIP1; VGLL1; ERF; HDGF; RBFOX2; TBL1XR1; ZNF146; NFKBIA; DEK; GRHL2; ZFP69B; PRDM10; ADNP; TBX21; UBTF; NFYB; BRIP1; ZNF32; NFATC4; ZNF302; HMGB3; WHSC1; ZNF629; RAN; CDYL; ZNF219; TCF7L2; ZIC3; PHF2; YEATS4; ZNF84; TCF12; HIF1A; DACH1; PAX6; ZEB1; KDM5D; ZBTB20; HEY1; TAF9B; JAK2; EYA1; PSPC1; NCOA2; RFX7; HMGXB4; CBX3; USP22; BCL6; ZNF85; ZBTB1; REPIN1; EN1; SUPT3H; PSMC3; ARID1A; MYBL2; VGLL4; SALL1; ID4; ZNF551; ZNF232; IRF8; RXRA; PATZ1; CHD9; ZNF544; BAZ2B; HMGN3; NUP62; HDAC9; BCL11A; TGIF1; ZKSCAN7; PBX3; RBPJ; TCF7L1; SUV39H1; HIRA; FLNA; CBFB; VPS72; NANOG; NCOR2; FOXO1; AEBP1; HOXB2; CNOT2; ASCL1; KAT6B; TSC22D1; SHOX2; MEIS1; MEIS2; RBPMS; INSM1; ZFPM2; MECOM; ZFP36L2; TBL1X; TFAP2C; IFI16; HOXB6; ZIC1; TRIB3; ZNF586