Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID81142 Pyrvinium GSE92742 NPC Human 6h 10uM EID0486
Types Number Response transcription factors
Up-regulation 82 TXNIP; XBP1; KLF9; CREB1; JUN; ARID5B; EGR1; FOS; DMTF1; ZNF274; RELB; MED13; FOSL1; NFKBIA; CNOT2; CIZ1; ZSCAN9; CALCOCO1; ZNF721; CIR1; CERS4; TFAP2C; ATF3; CBX4; SPDEF; TRIM22; L3MBTL1; FHL2; CALR; ZNF160; HDAC9; IFI16; IRF9; TRAK1; ELF5; MXI1; EGR2; HOXB6; ATF4; HDAC5; NFIL3; IRF8; TSC22D3; DDIT3; BBX; PKNOX2; HIPK2; TRIB3; IRF6; ETS1; HBP1; IL16; BACH1; NR4A2; BTG1; FOSB; ZBTB43; HOXB2; INSR; KAT2B; NR1D2; JUNB; GATA6; NR4A1; HOXB5; CTBP2; EMX2; TWIST1; NR2F1; MNDA; PEG3; ATF5; TOX; AES; LITAF; ZBED2; BCL11A; MEIS2; WT1; ZBTB16; ETV1; NFKBIB
Down-regulation 62 SOX4; DAXX; MAGED1; BRCA1; SOX2; ID1; NFATC1; HEY1; FOXC1; TCF15; GLI1; ZNF3; STAT5A; CARM1; ZNF33B; TDRD3; ORC2; ELK1; HDAC7; E2F3; DNMT3B; SREBF1; BCL11B; MYCBP; VGLL4; CARHSP1; HOXC6; PURA; SETD3; ID3; BAZ1A; HMGA1; RNF14; ID4; RBBP4; TRIM29; ZNF573; ZSCAN31; SSBP2; ZNF281; PRRX2; ZNF302; CCNE1; HES1; TRIM16; ELK3; MTF2; FOXJ1; TLE1; LEF1; MYC; PIR; HLTF; SATB2; TSC22D1; STAT4; MED24; INSM1; PAX6; MYCN; E2F2; RUVBL1