Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID81138 Plumbagin GSE92742 NPC Human 6h 10uM EID0486
Types Number Response transcription factors
Up-regulation 148 RELB; NFATC3; TFAP2A; SPDEF; SPIB; CIC; BCL3; CEBPD; JUN; PRDM14; NR1H2; MED25; ACTL6A; BARX1; ZNF350; SOX13; TCEA2; PROP1; PBX2; NFE2L2; WWP1; PEX14; CDIP1; ZNF671; ZNF205; CEBPE; NFKB1; E2F4; TULP3; HSF4; KDM5C; ZNF223; CERS4; ETS1; RFXANK; ZNF222; TERF1; VDR; WT1; PNRC1; COPS5; YAP1; ELF3; E4F1; ZNF576; SOX17; IRF6; TGFB1; ETV6; ZNF335; CD3D; NFE2L3; ZSCAN9; ZNF623; TRPS1; PHF1; EVX1; TCF21; MED14; TBX2; CNOT3; PIAS4; EHMT2; MED15; OVOL2; NOC2L; CIR1; ZNF180; NAB2; ZNF224; ZNF112; ZNF239; ZNF331; ZNF117; SUPT5H; HOXD1; MED12; HOXD3; TRIM24; RING1; GATA6; ZNF91; JUP; ZNF415; ZNF682; NR2F1; ARNT2; SOX18; KMT2B; KLF11; SPI1; ZNF83; HOXD11; TRIB3; ING4; L3MBTL1; EPAS1; ZNF444; IRF9; NR4A2; ZNF44; RBFOX2; CBFA2T3; MEIS2; AR; TRIM29; TGFB1I1; TDP2; ZBTB20; HOXB2; KLF6; TTF2; FOSL2; HOXA4; PEG3; IRF1; ERBB4; HSF1; ZNF580; ARID5A; IRF3; BANP; HOXB5; PIR; ST18; HLX; ZNF512B; ZBED2; ESR1; YEATS4; THAP7; KLF13; JUNB; TAL1; MYBL1; CCNH; FOXJ1; DACH1; STAT4; SNAI2; RSF1; EMX2; ZNF165; MECOM; SCAND1; HOXA5; HMG20B; NFKBIB
Down-regulation 220 KDM5D; KAT6A; CRK; SOX4; RHOA; FOXO3; ZBTB18; ATF1; BRPF1; SOX2; SMARCC1; CBFB; MLX; SMARCE1; PHF2; ZNF24; HOXC6; ZEB2; EP400; CCNC; GABPB1; ZBTB24; SOX11; NCOA4; NFKBIA; CBX5; SMAD2; TCF12; MED6; DDX17; ABL1; PATZ1; SETD2; YBX1; ASCL1; CREBZF; RNF4; PCGF2; NUP62; YAF2; ZNF672; KMT2A; ZNF384; ORC2; NRIP1; RXRA; ZFY; ATF7IP; EN2; HMGA2; ZHX3; GABPA; BMI1; JARID2; VGLL4; BRD3; USF2; ZMYM2; BTAF1; RBBP4; FOXJ3; MED1; PURA; KDM5A; TBL1XR1; TTF1; ING1; PBRM1; TSC22D3; TCERG1; NRBF2; IKBKAP; TERF2; TAF10; PREB; BAZ1B; UBP1; BATF3; HCFC2; LIMD1; HSF2; RFX5; ZEB1; NFATC1; HEY1; FOXC1; KDM2A; HMGA1; PIAS2; ELK3; TAF1D; BAZ2B; ZNF516; RFX7; SREBF1; WHSC1; TRIM32; TBP; NCOA6; ZNF248; ARID4B; POU2F1; SFPQ; CRY1; MBD2; FUBP1; BLM; BRIP1; BCLAF1; ZNF189; SOX10; ZKSCAN1; NRF1; DNMT3B; MAGED1; MYCBP; HMG20A; MEF2A; CREB5; HMGB3; COPS2; ATF4; GATAD2A; TRAK1; NFIB; NEDD8; UIMC1; CDYL; HLTF; NFIL3; SMAD3; TRRAP; TCF4; BASP1; ZNF443; E2F6; VEZF1; SIAH2; JUND; OLIG2; TSC22D2; ADNP; CCNA2; ARNTL2; NCOR2; ZNF23; HTATIP2; XBP1; MITF; MED23; PTTG1; ZNF423; FOXN3; SAP30; HIVEP2; CTR9; SMAD4; EGR3; ZBTB1; ING2; DDX5; LMCD1; PPARGC1A; ZNF652; ISL1; KAT7; AFF1; CCNT1; PBX1; ELK1; SETD3; ZNF107; PLAGL2; BAZ1A; RUNX1; REPIN1; CHD9; PBX3; KLF4; NCOA1; SATB2; CITED1; ZBTB43; EGR2; MED24; CHD1; IRF4; ING3; ZFHX4; ELF1; ASH2L; RNF141; ZFP36L2; MSX1; ETV1; ZNF131; IRX5; TRIM16; MYCN; MTF2; HOXB7; ENO1; ID4; MAX; SOX9; TOB1; OSR2; PFDN5; ZBTB16; MEIS1; PAX6; ZMYND8; MYB; ETS2; POU2AF1; TOX3; TBPL1; MAFB; E2F2; CEBPA