Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID81102	Bisindolylmaleimide	GSE92742	NPC	Human	6h	10uM	EID0486

Response Information :

Types	Number	Response transcription factors
Up-regulation	144	TFAP2A; RERE; ATN1; ZNF350; SPDEF; CAMTA2; PEX14; NEUROD2; CEBPD; TAF1C; HOXD1; SSBP3; ZNF34; JUN; NR1H2; PRDM14; VDR; NR5A2; TRPS1; NEUROG1; MED15; SHOX2; TERF1; SIN3B; NEUROD1; SOX13; SRCAP; TCF3; ARID1A; HMGXB4; TAF12; EGR1; ZNF623; TFAP2C; KLF11; FOS; VENTX; LIN28A; NANOG; OVOL2; ZNF74; KLF13; ZNF7; ZBTB18; BHLHE41; ZBTB48; CBFA2T3; TCF7L2; IRF6; HDAC9; LHX6; PRDM2; BRD4; HIRA; PIAS1; HIC2; PIAS4; HOXD11; SREBF2; CALR; ARNT2; ZHX2; ZNF557; ZNF467; ZNF580; MYCL; PBXIP1; ARID5B; ZNF215; TEAD4; CNOT3; ATF3; SP3; CBX7; CUX2; ZNF589; MEIS2; IRF1; TRIB3; ZIC3; MZF1; ELF4; FOSL2; CRYM; E4F1; ST18; ZNF264; DBP; HSF1; ELF3; AR; ESR1; WNT4; ZNF512B; HDAC5; MNT; HOXD3; JUP; ZFP36L2; EN1; ZNF532; DDIT3; ZNF593; INSR; ZNF12; IRF8; MECP2; GTF2F1; HOXB13; HLX; ERBB4; MNDA; VGLL1; RARA; TGFB1I1; TBL1XR1; LOXL2; HHEX; CITED2; MECOM; IRF9; MYBL1; NR4A2; THAP7; SOX17; CCNH; HBP1; ZNF232; TAL1; IFI16; KAT2B; ZNF91; ZNF331; ZNF217; FOXN3; IRF3; BACH2; PFDN5; DACH1; OSR2; HOXB2; PEG3; LEF1; WT1
Down-regulation	152	BRCA1; DMTF1; SIX1; ZMYM2; TBP; EP400; MAGED1; GATAD2A; KDM5A; IKBKAP; NFKBIA; ECD; LPIN2; SP110; MED6; NEDD8; HNRNPD; ASCL1; TAF1D; CBX3; EED; CBFB; BRPF1; CARHSP1; PSMC3IP; ZNF248; USF2; ABL1; ZNF672; HDAC2; ORC2; KMT2A; FOXO4; LIMD1; PSIP1; SMARCA5; HMBOX1; GCFC2; BAZ1A; DNMT3B; VGLL4; ID4; SMAD5; CREG1; DLX2; RAN; CARM1; AEBP1; PIAS2; HIVEP2; NFAT5; GABPB1; TP53; HMGN3; BCLAF1; SMAD2; HOXC6; TCF12; SFPQ; SSRP1; ZBTB1; TEAD1; SIX2; RBM14; MNAT1; DNAJC1; KDM2A; FHL2; PLAG1; RBBP7; ZNF410; BAZ2B; CDYL; CNOT1; TSC22D2; HSF2; ID1; PBRM1; GATA4; YWHAB; CRY1; NELFB; BRIP1; PURA; SMAD6; CTR9; DEK; NUP62; ZNF443; KDM5B; ADNP; MEF2A; CREB5; ISL1; ING3; HEY1; FOXC1; YAP1; ZNF23; BIRC2; BLM; CCNA2; BASP1; ZNF302; MEOX2; UBE2I; RBBP4; MAX; TRIM32; MBD2; TRIM16; RNF141; MTDH; NR1D2; PTTG1; MSX1; SETD3; ELF1; BMI1; ZNF131; PPARGC1A; TRRAP; ZNF423; MAF; RBPJ; NKX3-1; VEZF1; ID3; MITF; KLF2; RUNX1; LMCD1; TBL1X; ENO1; PRKDC; SATB2; ZBTB38; STAT3; IRX5; ETV1; ZMYND8; ASH2L; CCNE1; TOX3; HLTF; TBPL1; PBX3; SCAND1; TSC22D1; TOB1; RUVBL1; E2F2