Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID81051 Hydroxychloroquine GSE92742 NPC Human 6h 10uM EID0486
Types Number Response transcription factors
Up-regulation 52 TFAP2A; SPDEF; ETS1; OVOL2; ELF3; WWC1; ZNF329; ZNF33B; IRF6; CEBPD; GATA6; MEIS2; SOX9; PLAGL1; TCF21; SOX17; BNC2; TRIM29; ERBB4; PITX1; ZNF217; TRPS1; INSM1; JUP; UBE2I; TRIB3; KLF5; KLF10; NR4A1; ZSCAN18; HOXB13; EGR3; TFAP2C; ZSCAN31; EGR2; KLF11; SNAI2; JUNB; NR4A2; ZNF331; BACH2; BIRC2; FOXF1; ATF3; ZNF117; BTG1; ESR1; FOXF2; TWIST1; ZNF165; WT1; PEG3
Down-regulation 76 ZMYM2; NCOA4; HOXC10; YAF2; SMAD7; SALL1; PSPC1; GTF3A; ZBTB18; CHD3; ERBB2; SIAH2; TRIM22; HOXC6; HOXD11; NR1I2; HLF; NFIC; CARM1; TFEB; BATF3; TADA3; PIAS2; ORC2; PHF8; RNF6; NCOR2; ZMIZ2; ETV5; TAF10; PMS1; POLR2A; BAZ2B; MAGED1; MAZ; RNF14; ZNF281; TTF1; RREB1; SAP18; HMGB1; LMCD1; JARID2; SATB1; PCGF2; ABL1; CCDC59; ZNF593; ELF1; TSC22D2; SSBP2; SMAD6; KAT2B; DDX5; CREB5; ZNF430; EYA2; SATB2; MED1; BMI1; BATF; SCAND1; ING3; MAFB; ASCL1; SAP30; PURA; PIR; FOSB; ZNF266; NFKBIB; ZBTB16; BCL6; ETV1; E2F2; CEBPA