Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID81046	Bosutinib	GSE92742	NPC	Human	6h	10uM	EID0486

Response Information :

Types	Number	Response transcription factors
Up-regulation	182	GATA3; OVOL2; JUN; NFIL3; SOX17; NFKBIA; ZNF623; TFAP2A; ELF4; MNDA; MED15; ADNP2; CEBPD; CEBPB; MEF2D; FOSL2; JUP; TAF1D; ZNF467; TRPS1; NFE2L2; HSF1; NFATC3; NR5A2; NR4A3; ZNF350; MEF2C; TRIM24; TERF1; ETV6; REL; MED25; IRF1; VDR; MECOM; SOX13; NR4A2; MYCL; ZNF34; NR5A1; E2F4; KLF11; IRF6; LIN28A; TEAD4; ZNF250; EP300; ENY2; SPDEF; CD3D; BNC1; ZNF74; ARNT2; ATF3; WWP1; HSF4; ST18; BCL3; TFAP2C; PIR; TAF12; TCF7L2; ESRRA; KLF13; SOX12; ZFY; ZNF7; ZNF239; DLX5; EYA2; PEG3; E4F1; AHR; TGS1; ZNF331; SSBP3; FOS; TCF3; ZNF394; FEZF2; COPS5; ZNF335; GRHL2; JUNB; NR1H2; ESR1; NFATC4; HIC2; NR0B2; ZNF195; ELF3; WT1; ZBTB3; L3MBTL1; NFKB2; SIX6; ZNF44; BHLHE41; ZNF444; GATA6; HLX; CERS4; RNF138; ARID5B; SOX18; NKRF; HIPK1; TRIP11; TRIM29; ZNF532; HOXD3; CNOT3; PRDM1; NR0B1; ZFHX3; HOXD1; ZNF682; HHEX; FOXE1; DDIT3; VGLL1; HDAC5; SNAPC4; MEIS2; EGR1; EPAS1; PNRC1; TRIB3; ZNF692; MYBL1; DBP; MEIS1; HDAC4; PRDM10; SOHLH2; PHIP; FOXA2; IRF3; IRF9; ZNF12; ZNF165; ZBED2; TCF21; PBXIP1; RUNX3; STAT1; ISL1; ZBED1; ZFP36L2; HOXB2; MYRF; CBX7; HOXB7; ZNF573; ZNF593; ERBB4; KLF6; TCF7L1; CCNH; YEATS2; FOXD1; ZNF264; ARID5A; MYC; CEBPG; ZFPM2; HOXB5; NFAT5; KLF5; TBX3; THAP7; ZNF217; FOXF2; NKX2-2; OSR2; SCAND1; FOXA1; HOXB6; MAFB; RSF1; ZNF91; HOXA5
Down-regulation	247	ZMIZ1; DMTF1; ATF1; CREB1; RERE; SMARCE1; RHOA; CBX5; SIX1; GATAD2A; MAGED1; ZNF24; FOXO3; LPIN2; USF2; ZBTB18; SMARCA5; PSMC3IP; KMT2A; SMAD1; SUV39H1; ZNF140; BAZ2B; SMARCC1; ZKSCAN7; MED13; MLX; HDAC2; HNRNPD; CBFB; TBP; NONO; YAF2; ID4; MED6; MED1; BRCA1; SETD2; HMGA2; BASP1; GABPA; BAZ1B; ECD; EDF1; SUZ12; IRF2; PBRM1; SPEN; NFIB; ZMYND11; YWHAB; HIVEP2; TAF1A; PARP1; CCNC; TCERG1; HSF2; ZNF45; TCF12; ZMYM2; NELFB; PATZ1; HDAC3; LIMD1; MEF2A; ING2; ZNF84; HOXC6; ZBTB24; ZNF23; HMG20A; PSIP1; SMAD2; EP400; RNF14; IL16; EZH2; BRD8; ZEB1; E2F6; AATF; NCOA4; CCNA2; RAN; NRBF2; USP22; HCFC2; EN2; SMAD4; ASCL1; YBX1; ELK3; TAF9B; CRY1; FOXC1; ZNF510; MEOX1; TP53; DNMT3B; SIAH2; NPM1; RFX7; CDK8; ZNF143; BBX; ENO1; TADA2A; BRIP1; MEOX2; ZNF302; SP110; CBX3; PMF1; TRRAP; BCLAF1; PIAS2; ZNF672; ORC2; RFC1; SND1; ZSCAN18; BRD3; HOXB9; BMI1; ANKRD1; SATB1; CDYL; RBBP4; ELK1; CHD9; PCGF2; URI1; E2F5; KDM5A; ING3; ZEB2; SIX2; SMAD5; XBP1; NCOR2; HMGB1; SUPT4H1; CHD7; TFDP1; RBBP7; ZBTB20; EWSR1; POU2F1; JUND; NRF1; MAX; SMAD3; NEDD8; ZBTB14; CREG1; ZBTB40; DDX5; NFYB; CARHSP1; CRTC1; BTAF1; FOXJ3; UBE2I; LHX1; PBX1; CITED1; TSC22D3; VEZF1; BLM; ATF6; ZNF329; ZBTB1; ZNF22; NR2F1; FHL2; TCF4; PKNOX2; PRDM4; PAXBP1; ZBTB38; HOXC4; KDM5B; TSG101; C1QBP; ZNF189; NCOA1; CUX2; HEY1; CREB5; TGIF2; UIMC1; TRAK1; MAZ; CTR9; ZIC1; TRIP4; SOX15; BATF; XRCC6; PURA; ZNF146; SOX9; RBBP8; EED; PPARGC1A; IRX5; RBM14; TAF9; SIX3; NLK; HOXC10; BAZ1A; CITED2; ZNF266; STAT3; ETV5; MKL2; NFE2L1; SLC2A4RG; ETV1; EYA1; KAT7; BIRC2; NR1D2; MNAT1; ASH2L; NPAS2; MTF2; SETD3; TAF7; TGIF1; ZNF432; ZNF200; CEBPZ; CHD1; HLTF; EGR3; NKX2-1; PBX3; CTBP2; TCFL5; RUNX1; ZNF131; PAX6; DACH1; MYB; RUVBL1