Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID81008	Plumbagin	GSE92742	NPC	Human	6h	10uM	EID0484

Response Information :

Types	Number	Response transcription factors
Up-regulation	87	CNOT3; KDM5C; PNRC1; IRF3; LZTR1; WT1; KDM4C; RING1; ZNF692; CIC; ZNF574; ZXDC; GTF2IRD1; MED25; MLXIPL; SPI1; MZF1; MED15; ACTL6A; JUNB; NFATC3; NR0B1; TGFB1; E4F1; ZNF335; MED12; KMT2D; ZBTB17; SOX18; EPAS1; STAT4; KLF9; TFAP2A; STAT6; KMT2B; HLX; BARX1; CBFA2T2; SUPT3H; INSM1; ZSCAN9; PAWR; MEOX2; HSF1; SMARCA1; NR1H2; EVX1; ELF3; PSMC3; SOX17; RUVBL2; HDAC9; HOXD1; NR1I2; BANP; MYBL1; ZBED2; SUPT5H; ST18; RUVBL1; ETS1; IRF9; SHOX2; FOXF2; BHLHE41; JUN; ZNF544; DDIT3; CD3D; CALR; PIR; NFKBIB; ZNF331; BNC2; HOXC10; CDK7; YBX3; DACH1; ESR1; FOXD1; HOXB2; SPDEF; MEIS2; ZNF165; KLF6; TRPS1; IRF6
Down-regulation	137	KAT6A; SOX2; FOXN3; GABPB1; SOX4; JARID2; SMARCC1; ZBTB18; HSF2; ZBTB24; ZNF516; SUZ12; HMGA2; E2F6; TBL1XR1; MLXIP; FUBP1; KDM5D; ELK3; TULP4; SUB1; CHD1; FOXJ3; SP3; CREB5; CCNC; BLM; RFX7; FOXC1; RFX5; CREBZF; TP53; NRBF2; SETD2; MYB; FOXO3; ABL1; PURA; TTF1; KMT5A; ZEB1; TSC22D2; ELK1; ELF4; ASCL1; RNF4; WWC1; NFKBIA; CBFB; INSR; ZBTB16; POU2F1; PATZ1; LIMD1; BRPF1; PREB; NFAT5; MED23; RHOA; HEY1; NCOA1; CDYL; ZNF281; CHD7; BRD3; MYCN; RBBP5; NR2F2; NCOA6; ZHX3; NAB1; TBL1X; NFIB; DNMT3B; ING2; RNF111; TGIF2; MYCBP; ZHX2; ZKSCAN1; KDM5A; KMT2A; PCGF2; ZNF43; SMAD3; CBX3; ELF1; VGLL4; JUND; NCOA4; RYBP; BASP1; EN2; CRY1; SMAD2; UBP1; AFF1; BATF3; CUX1; RBBP4; CBX6; MED1; ZNF430; ZNF211; HNRNPD; ZMYND8; REPIN1; HOXC6; STAT3; PHF20; PBX1; CREB3L2; ARID4B; ADNP; PHF2; HMG20A; BMI1; ETV1; VEZF1; RBPJ; MYRF; EGR3; FOXO1; ZNF131; CITED2; YWHAB; MITF; NFE2L3; SOX9; TOX3; SAP30; ZEB2; ZNF652; MAGED1; SATB2; CRK; SUV39H1