Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID81001 Oxamflatin GSE92742 NPC Human 6h 10uM EID0484
Types Number Response transcription factors
Up-regulation 104 EGR1; FOS; CREG1; TCFL5; FOXO4; JUNB; NFKB2; FOSB; FOSL1; ATF3; TBPL1; WWTR1; ZNF586; NR4A1; PPARD; IRF7; TXNIP; SMARCD3; ELF5; SP110; ZNF304; PBXIP1; ZNF432; NR4A2; MLXIP; TOB1; ZNF44; EGR3; MXI1; SP100; ZNF91; L3MBTL1; SPIB; ZNF551; ZNF124; CBX4; BBX; ZNF331; UBE2B; LOXL2; ZNF593; RBBP5; SIRT7; ZNF394; ZNF264; AR; TRIM22; RYBP; ZNF224; CTR9; ZNF175; DDIT3; CREB3L1; CCNT1; ZBTB11; CITED2; TLE4; JUN; ZNF430; CREB3L2; ZNF654; CDK7; IRF1; KLF11; WT1; ZNF587; NR3C2; AFF1; BCL3; KLF2; AHR; ZNF211; MYC; NR2F1; PURA; HHEX; MITF; TGFB1; ATF6; SETD3; KLF10; TBX3; ZFP36L1; ZBED2; VDR; PEG3; KLF13; HOXD1; NFIB; BRD2; OSR2; ZBTB43; SOX9; LITAF; YWHAB; BRD4; ESR1; NFKBIB; KLF6; NR2F2; TOX3; KLF5; HOXC6; CRK
Down-regulation 118 GABPB1; HDGF; PMF1; SMARCA4; TCERG1; FOXM1; TCF20; USP22; CTCF; MAZ; ATN1; SCMH1; NR2F6; GRHL2; ZBED1; SNW1; HMGXB4; NUP62; TCF3; SMARCE1; CENPB; SOX2; ERBB2; NFKBIA; SP3; CTBP1; BPTF; SMARCB1; WDHD1; ZNF219; ERCC3; SUPT3H; LHX2; TCF12; TCF25; HMGN3; PAX6; VGLL4; DEK; ZNF32; GLI2; CBX3; STAT5A; ADNP; PHIP; ZIC1; ZNF146; HEY1; SALL1; JARID2; RXRA; TLE1; ZFP64; CDYL; REPIN1; BATF3; NCOR2; SMAD3; ZNF532; HNRNPD; EN1; SREBF2; TSC22D1; CCNA2; CUX2; SUV39H1; JAK2; PCBD1; MKL2; YEATS4; CNOT6; CBFB; NCOA2; CEBPG; ZBTB38; USF2; PHF2; RREB1; DDX17; NRIP1; WHSC1; TEAD4; INSM1; TP53; E2F3; ZNF302; ZNF629; ZNF226; ARNTL2; MED24; MYCN; ZHX2; GTF2I; BRIP1; ZFP36L2; TCF4; MECOM; ZMYM2; DACH1; CEBPB; HMGB1; AEBP1; HMGB2; SOX17; BCL11A; MYB; TRIP6; RBBP4; ID4; PIR; RAD21; TAF9B; RUNX3; FOXG1; ATF1; TRIM29; TRIB3; MTA1