Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80922 Hydroxychloroquine GSE92742 NPC Human 6h 10uM EID0484
Types Number Response transcription factors
Up-regulation 87 TFDP2; NR1H2; TXNIP; FLI1; PFDN5; SALL2; YY1; TAF12; PBX3; HOXA5; MXI1; UBE2I; LOXL2; ZNF331; TCF7L2; MTA2; TTF1; AEBP1; ZNF215; SSBP3; HOXA11; ARRB1; FOXN3; ZNF516; TFAP2A; ZBTB18; CSDE1; MAFF; ZNF654; NR4A3; AIP; SOHLH2; AR; CALR; PRPF6; CTBP2; POLR3C; RUVBL2; CDIP1; JUND; DACH1; RCOR1; MYB; HIPK3; VPS72; HTATIP2; MAX; HOXB5; FOXO1; NANOG; HEY2; HOXB6; TFAP2C; PCGF2; ZNF211; NR2F1; ZNF589; TP53; MNDA; TBX3; DAXX; HIRA; NKX2-1; GTF2I; NFE2L3; HOXB7; ZNF467; KAT6B; FOXF2; ARID4B; ZFP36L1; HBP1; TFDP1; ZNF22; NFATC3; BTG1; TAF9B; KLF6; CUX2; OSR2; YBX3; TWIST1; SPDEF; IRF6; FOXF1; PEG3; ZNF586
Down-regulation 103 EED; ASCL1; SCAND1; MED13; XBP1; PHF20; ZNF329; NUP62; BPTF; INSM1; PSIP1; HES1; IKBKAP; MKL2; ELF4; CENPF; BASP1; PLAGL2; DNAJC2; DNMT3B; TSC22D3; BRCA1; HIVEP2; COPS2; CHD3; RAN; YEATS2; SP100; ETS2; SMAD3; YBX1; USP22; NPAS2; SMAD2; ZNF148; ZNF160; NFE2L1; PITX2; MED23; ACTL6A; BLM; ZNF721; NFIL3; ZNF443; ZNF12; MEOX2; DMTF1; CREBZF; MEIS1; C1D; ZNF131; SMARCA1; TOB1; RNF111; TLE1; FOSB; NCOA6; WWP1; ZKSCAN1; PIR; MEOX1; TOX3; BATF3; PAX5; RBBP7; ZNF226; UBP1; BAZ1B; JUNB; CTNNB1; ZBTB38; BBX; HDAC9; E2F8; ZNF529; HMBOX1; MYCN; EHF; ADNP; ZBTB1; SOX17; NRIP1; MYC; STAT1; STAT3; SMAD7; HOXD1; AHR; NFAT5; SMAD1; FOXJ3; MEF2A; IRF8; MAF; MECOM; GMNN; ATF1; ID4; MED1; SNAI2; ZMYM2; MAGED1; NKX3-1