Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80910 Pyridine-2,4-dicarboxylic-acid GSE92742 NPC Human 6h 10uM EID0484
Types Number Response transcription factors
Up-regulation 71 MTF2; HOXA5; HTATIP2; MYB; TFDP2; FOS; ZNF274; SALL2; PBX3; HMGB3; SALL1; MAFF; CXXC1; PREB; TCFL5; ZBTB18; JARID2; AFF1; DLX2; DDX5; TSC22D1; BCLAF1; RUVBL2; CHD1; CTBP2; PIR; ZSCAN31; TFCP2; SFPQ; MYCL; AHR; BTG1; BAZ2B; BHLHE41; RBPMS; KAT7; CTR9; HEY2; ETS2; HSBP1; TFEC; KLF6; BATF; LIN28A; FOXL2; FOXD1; DAXX; ZNF423; HOXC6; JUN; VEZF1; BRD2; KAT6B; HHEX; ZNF587; ZFP36L2; IRX5; YWHAB; TOX3; NANOG; ESR1; ARID4B; SAP30; OSR2; ZEB2; MXI1; HOXB6; BASP1; ZNF165; PUF60; NFKBIB
Down-regulation 32 SCMH1; CCNC; CBX4; SMARCD3; AES; TAF9; SUMO1; TLE2; PAX5; SMAD1; KDM5D; PAX9; CNBP; MECP2; WWC1; MECOM; CBX6; RNF6; PITX1; ZFP36L1; SP140L; ZNF512B; POU2AF1; ZNF415; CUX1; BRD4; MEIS2; ZMYM2; FOXG1; TRPS1; TRIB3; SNAI2