Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID80874	Nvp-bez235	GSE92742	NPC	Human	24h	10uM	EID0483

Response Information :

Types	Number	Response transcription factors
Up-regulation	128	MXI1; MYC; DDIT3; CALCOCO1; EZH1; VGLL4; FLNA; KDM4C; ETV5; MZF1; ZMIZ2; IKZF1; CAMTA2; KLF6; BHLHE41; COPS2; ZNF467; ZNF506; STAT6; CREG1; ZNF529; PNRC1; ZNF83; FOXG1; PDLIM1; HLF; RXRB; ZXDC; CBFA2T2; KLF2; BRD8; ATF4; CTBP1; HBP1; TLE1; FOXO3; KDM5B; CIZ1; TERF1; KAT2A; SERTAD2; ARID5B; FOXO4; CHD3; JUN; NCOR2; PLAGL1; PHF1; KLF7; PRMT2; MEN1; PRDM2; HDAC5; ZNF34; MAFB; TSC22D3; LEF1; FLI1; KDM5C; RELA; POU4F1; HTATIP2; ZNF184; ELF5; NELFB; IRF4; TCF7; ARID4B; PSPC1; ZNF91; HOXB2; ING4; ZNF692; LOXL2; SCMH1; IRF2; HOXC6; NPM1; PBXIP1; NFE2; BRD2; BACH1; HMBOX1; TRIM22; BCL11A; BCL6; POU2AF1; ZNF721; SMARCA2; LDB1; IRF1; HIRA; ZBED2; PHF8; TCEA2; HOXD1; SOX17; EN1; ZNF589; ZNF160; HOXB6; TGIF1; MED15; PAWR; IRF6; ZBTB20; SOX13; ST18; HOXB7; PITX2; CBX7; TRIP6; BTG1; BBX; NRIP1; NKX2-2; NFKBIB; BRD4; KLF5; NR1H2; CERS4; GATA6; HHEX; MNDA; EGR3; HMG20B; KAT6B; JUP
Down-regulation	129	CCNA2; MYBL2; CENPB; CENPF; WDHD1; SUMO1; PARP1; E2F6; ESRRG; SUZ12; PRKDC; YEATS4; ING2; SMAD4; TAF9B; SIX3; WDR77; FOSL2; DACH1; GMNN; ZNF45; VPS72; PLAGL2; BRIP1; MTA2; TAF5; DEK; KDM5D; PBX3; SMAD6; THAP11; ZNF239; GTF2A2; RBBP8; ACTL6A; RAN; RB1; HNRNPD; CHAF1B; GABPB1; POLR3F; HMGA2; MED7; BIRC2; MED20; MED17; TAF1A; EED; NUP62; CALR; E2F2; RUVBL2; SFPQ; CARHSP1; DAXX; PSMC3; HMGB3; SSRP1; LIMD1; NFATC3; RBBP4; ZNF331; STAT1; ASH2L; PITX1; WHSC1; HLTF; CUX2; HMGB2; CRY1; PA2G4; BRD7; ID3; SLC2A4RG; BRCA1; ZEB1; BLM; SMAD5; TGFB1; E2F8; SAP30; ID1; SFMBT1; PAX6; MYCBP; TCF21; CBFB; HMGB1; MED6; CBX5; CREM; TBP; ZFP36L2; ATF5; ILF2; NHLH2; PSMC3IP; SMARCA5; CCNE1; BASP1; TEAD1; SATB1; YWHAB; SSBP2; SETD3; AGO2; MYBL1; ATF1; MITF; EZH2; HSBP1; SALL2; MEIS1; ZNF443; FOXN3; ZFHX4; SAP130; MYB; NR2F1; TGIF2; SUV39H1; NPAT; ETV1; RUVBL1; NR4A1; TFDP1; CDK2; MEIS2; ZNF423