Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80858 Im-12 GSE92742 NPC Human 24h 10uM EID0483
Types Number Response transcription factors
Up-regulation 72 ATF6; CEBPE; HIVEP3; HOXC5; CREB3L2; HOXD10; SETDB1; PFDN5; AR; NKX3-2; ZNF688; ATN1; PCGF1; FOXD1; NFE2; EYA1; IRF6; ZNF516; SRCAP; CALR; SIX3; KDM5B; AIP; ZNF580; WNT4; HOXA11; HOXC4; POU2AF1; HEY2; HOXD11; RBPJ; CHD8; GATA1; EMX2; GFI1; LOXL2; JUN; SPIB; PITX1; MYB; ARNTL2; TCF7L1; CCNH; E4F1; SIX2; SREBF2; NFATC4; CHD4; NFATC1; HOXC6; HHEX; MXI1; ESR1; FOXO3; BRD2; CEBPB; BAZ2B; ZBTB18; BTG1; ARNT2; CITED2; CHD9; PBX3; ZBTB20; ATF5; SPDEF; HOXB6; HOXB2; SCAND1; MNDA; TFDP1; RUVBL1
Down-regulation 156 CREB1; UBP1; YEATS4; TBX3; CRK; TRIM22; SMAD7; GMNN; USP22; PSIP1; NFYB; NRIP1; NR2C1; BCOR; EED; NUP62; ZBED1; IRF7; TOPORS; KAT7; RB1; HIF1A; ZNF468; SMAD4; SMAD6; MED4; NR1D2; E2F5; ZMYM2; TDRD3; RBBP5; THAP1; HIVEP1; REST; RNF111; ZNF217; ZFP64; MED7; WWTR1; TFAM; ACTL6A; SFPQ; FOSL2; BCL10; WWP1; TERF1; ZZZ3; ING2; TAF1A; DEK; CHD1; PLAGL2; TAF9; NPAS2; HLTF; KLF10; E2F3; RNF138; TRIM32; ERBB4; MED6; ZNF189; ATF7IP; SNAI2; ETV1; HES1; RBPMS; RSF1; TAF4; ZNF430; HMG20A; DMTF1; KLF2; XBP1; CTBP1; NR3C2; ZNF131; ATF1; CDK2; ASH2L; TGFB1; MEN1; RBBP4; NKX3-1; E2F8; PHF20; ZKSCAN1; ZSCAN18; CDYL; BBX; PPARGC1A; ZEB2; ZNF14; FOXN3; ERG; ZNF652; HOXB13; TEAD1; CRY1; CTNNB1; DNMT3B; STAT1; HIC2; HEY1; TERF2; ZBTB38; HLF; TMF1; ZNF329; STAT3; HMGA2; MDM2; BRD3; EGR1; ETS2; CDK8; MYBL1; JARID2; RREB1; TCF7; SOX17; CCNE1; CBX3; ZFPM2; KDM5D; ID3; SSX1; SMAD3; TCFL5; TDP2; EGR3; HDAC9; SMAD5; TRPS1; BACH1; NR4A1; SMAD2; MEIS1; CTR9; ZNF160; ZBTB1; IKBKAP; ZNF107; TRIP6; CBFB; MAGED1; IRF8; HOXD1; ID4; IFI16; FOXJ3; ING3; BRCA1; LEF1; ZIC1; GATA6