Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID80791	Hydroxycholesterol	GSE92742	NPC	Human	24h	10uM	EID0483

Response Information :

Types	Number	Response transcription factors
Up-regulation	69	ADRB2; FOSL1; MYC; DNAJC2; NFIL3; EMX2; DDIT3; MLX; JUN; HIVEP1; RELA; CAMTA2; RELB; JAK2; CEBPB; TLE1; TSC22D1; CCDC59; ESR1; SSX1; FHL2; ATF3; EDF1; KLF2; HTATIP2; DEAF1; ARID5B; ZNF394; PDLIM1; CREB3L1; ZNF337; ZKSCAN1; SIAH2; XBP1; NPAS2; NRIP1; TRIP6; SP100; FOSL2; HOXB2; HMGA1; NFKB1; NKX3-1; NPM1; FOXD1; MECOM; KAT2B; BANP; CDK7; SATB2; ZBTB20; TRIM16; BHLHE40; PIR; ERBB4; HMGA2; SMARCA2; HOXB6; BATF3; RNF6; MNAT1; HOXB7; JUNB; ZNF589; CBX7; MED15; LEF1; WT1; BASP1
Down-regulation	92	SOX11; SOX4; TAF9B; SMARCE1; HAND1; WWTR1; TFDP2; SREBF2; APEX1; GTF2I; EPAS1; MYCN; TCF7L1; PBX1; ZNF45; CARHSP1; WNT4; SMAD6; ETV1; LIN28A; KDM5B; CBX5; ZEB1; NKX2-1; TOX; RBBP4; ARID4B; HLTF; ZNF711; ZNF219; DACH1; MNT; ZNF22; ZFP36L2; ZNF43; E2F2; ASCL1; ID4; MYB; TCF7L2; ZMIZ1; ZBTB18; HMGB3; ARID1A; GLI2; TGIF2; ZNF83; TCF3; SAP30; EGR2; MED14; MEIS1; ISL1; PBX3; TLE4; ID3; RUVBL1; ZFHX4; ZNF93; TRIM22; TRIM29; ZNF423; RAD21; RCOR1; HOXC6; NR2F1; SALL2; SSBP2; MEIS2; NFATC4; ZBED2; RFX5; BAZ2B; MAFB; TCEA2; PITX1; NEUROD1; MAGED1; CALR; BBX; PEX2; MTF2; PEG3; ZBTB1; ID1; AEBP1; TFAP2A; TOX3; JUP; CITED2; HMGN3; IRX5