Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80764 Purpurogallin GSE92742 NPC Human 24h 10uM EID0482
Types Number Response transcription factors
Up-regulation 116 NFKBIB; MEF2D; RHOA; SNAI1; ZNF671; NOC2L; ZFP36L2; SIRT7; ZNF205; TLX1; FOXL2; NFKBIA; GFI1; CREG1; HDAC11; GATA4; KLF6; MXI1; MZF1; SREBF2; FOXG1; FOXD1; FOXO3; SAFB; EYA2; RFXANK; TBP; TCF21; HIPK2; ZNF282; KMT2B; MED27; ARNTL2; DLX2; PITX1; BARX2; POU2F2; GATAD2A; HOXA11; FLNA; TSC22D4; ATF6; E4F1; SCAND1; TRIM16; JUND; PFDN5; RUVBL2; NELFB; ZNF264; ALX1; KDM5B; PAX6; POU2AF1; DNAJC1; SOX2; NAB2; RXRA; FOXJ1; ZNF711; VGLL1; SOX9; SATB2; HEY2; TULP3; EYA1; PDLIM1; TRIM25; TFCP2; CARHSP1; GATA1; TCF4; TCF25; NKX2-2; TP53; GLI2; ABL1; HEY1; USF2; BATF; NFATC1; ZNF516; UBE2I; ARID5B; TULP4; MED16; BTG1; NFE2; SIM2; GRHL2; HIRA; ID1; HHEX; TCEB2; IRF6; MYRF; MXD4; WWTR1; FOXF1; PBX3; CALR; HMGB3; CEBPB; EDF1; SIAH2; KLF9; MSX1; SALL1; TBPL1; KLF2; KAT6B; MYCN; ESR1; MEIS2; RUVBL1; MTA1
Down-regulation 153 DMTF1; CREB1; NR3C2; C1D; DEK; BRCA1; E2F8; HDAC6; PHF20; CERS6; TRIM22; TSC22D3; PPARGC1A; IKBKAP; CHD1; NUP62; ZNF7; ERBB4; NFIL3; ZNF32; RAN; ZNF654; ZNF44; ZNF33B; ZNF140; HOXB6; TAF9; SFPQ; ZNF248; NR2C1; CREBL2; UBE2B; ZNF623; RORA; TCF7; ZNF3; RNF111; SMAD7; TAF11; ARID5A; ZZZ3; BRCA2; MED4; CCDC59; BTAF1; ZNF107; MED7; TERF2; RNF138; NFYB; ZNF12; CRYM; WWP1; SP100; KLF4; ATF2; ZNF195; CHD9; NKX3-1; REL; BPTF; HOXD1; XBP1; ZNF468; TERF1; HOXB13; CREM; ZNF512B; EGR2; ZNF180; ZNF587; ZBED1; TLE1; ZFPM2; FOXN3; PATZ1; SNAI2; BRIP1; ZSCAN16; ZNF14; FOSL2; ZNF267; PLAGL1; GMNN; THAP10; PHIP; IRF7; HMG20A; NFIB; SAP30; MAF; DNAJC2; EED; ZNF131; IRF8; REST; CTR9; HOXC10; BATF3; ZNF160; NCOA2; SIX1; ZNF529; TDRD3; HDAC9; SALL2; JARID2; STAT6; CUX1; MEOX1; ZNF443; TRIM29; ZNF329; HOXC6; ZBTB1; ING2; NR4A1; HOXD3; HMGB2; ATF3; ZNF721; ZNF83; DNMT3B; NR4A2; EGR3; CITED2; TBX3; ZEB2; MEOX2; TOX; TCEA1; FOXJ3; HMGN3; TRIP6; ASCL1; VDR; SAP18; AHR; CRY1; LEF1; RB1; SMAD2; KLF10; NFAT5; TOX3; BASP1; ZNF91; ZNF217; ERBB2; CD3D; ZMYM2; HOXB2; ETV1