Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID80761	Plumbagin	GSE92742	NPC	Human	24h	10uM	EID0482

Response Information :

Types	Number	Response transcription factors
Up-regulation	259	HOXA5; KDM5C; NFKBIB; IRF6; CNOT3; NFATC4; ZNF331; ZNF444; GATA3; AIP; ZNF335; THAP7; ATF3; NR1H2; HSF1; E2F4; ZNF165; SOX13; CBFA2T3; VDR; HLX; REL; PROP1; IRF3; TTF2; BARX1; PRDM14; PNRC1; HOXA3; NUP62; SPDEF; MAML3; CEBPG; WT1; MED12; TRPS1; HOXA6; E4F1; SIX6; ZNF816; ZNF835; ZNF701; SOX18; JUN; RFX1; HOXA4; HSF4; EVX1; TEAD3; MED25; NR5A1; TBX1; HOXC5; ZNF34; MED15; TCEA2; RAD21; DDIT3; TUB; NCOA3; CDIP1; LZTR1; ZNF74; CBX4; TONSL; SOX17; ZNF155; KLF9; ZNF550; ZNF239; DOT1L; PEG3; BNC2; NFE2L2; RING1; HDAC9; ZNF576; CDX1; MZF1; FOXF2; ZNF205; CAMTA2; CSDC2; SNAI2; ZNF224; KLF6; TLE2; KLF11; ESR1; NR0B2; ELF3; FEZF2; THRB; SIX5; SNAPC4; SUPT5H; VGLL1; TAF1C; RARG; NOC2L; JUP; TAF6L; FOXE1; KLF13; ZFHX2; SMARCD2; ZNF75D; RFXANK; AR; PCGF1; ZNF623; ZNF593; ZNF195; HOXB1; TFAP2A; ZNF175; ZNF264; CEBPE; ZKSCAN4; ST18; ING4; EMX1; ZNF688; VPS72; ZNF665; ZNF611; MED14; MLLT1; TP73; POU4F2; SIRT7; OVOL2; SNAI1; POU2AF1; ZNF557; PSMC3; ZNF141; ZNF544; STAT6; FOXH1; EPAS1; CCNH; CEBPD; TGFB1; MAFF; EHF; PPP1R13L; POLR3C; RORC; SPIB; SCRT1; IRF9; PHIP; CEBPB; LHX6; LHX3; ETV2; ELF4; ACTL6A; GBX1; NR1H4; SRCAP; NR1I3; ZNF415; TRIM29; NFE2; ARID5B; ZNF345; IRF7; ZNF91; ZSCAN9; ANKRD1; SMARCB1; SP100; ZFPM2; WWP1; HOXD1; MYBL1; ZNF160; BNC1; FOS; PDLIM1; ARID5A; EN1; MECOM; TFAP2C; ZBED2; ZNF580; PAX5; KDM4C; ATOH1; HHEX; HOXB2; BANP; ZHX2; ACTL6B; ZNF587; ZNF44; PRDM2; BHLHE41; BCL11A; ZIC3; ERBB4; TULP3; TSHZ2; LIN28A; CERS4; FOXA2; SUPT3H; ZNF133; YEATS4; ZNF467; NEUROD2; ZNF215; SPI1; GATA6; SIRT2; NEUROD1; EMX2; ZNF83; PAWR; RBFOX2; AEBP1; TCF21; HOXB5; ZNF573; ZNF117; DAXX; WNT4; ZBTB20; IFI16; ZNF232; MYCL; NR0B1; TDP2; FOSB; CREBL2; CBX7; AHR; IRF8; TBX3; INSM1; ELF5; HBP1; CALR; RORA; TRIB3; ETS1; ZNF423; XBP1; TGIF1; NR1H3; MEIS1; HLF; CD3D; HIRA; ZNF721; DACH1; MEIS2
Down-regulation	389	RHOA; SMARCA5; KDM5D; HMGA2; CCNA2; RBBP4; EZH2; MED23; BRD8; RFX5; KAT6A; ZNF292; SMARCC1; TCF12; SFPQ; SMARCE1; PHF2; USP22; PCGF2; MAGED1; IKBKAP; AATF; SOX2; AFF1; TCERG1; KDM4A; PSIP1; SMAD4; CRK; SETD2; TBP; SPEN; MED6; SOX4; ADNP; ATF7IP; SMARCA4; HES1; HMG20A; ZNF189; ZBTB18; NCOA4; NONO; CENPF; CBFB; ELK1; EYA1; RCOR1; BLM; KAT7; PMF1; CITED1; ISL1; BIRC2; GABPB1; ID2; E2F6; JARID2; HSF2; TRRAP; BAZ1B; HEY1; UBE3A; ETV5; ZFY; ZNF84; UBP1; RERE; EP400; PBRM1; MED1; ELF2; SUV39H1; TBL1XR1; BCOR; SOX11; YBX1; CREBZF; RLF; TFDP1; BCLAF1; CTR9; HCFC2; ZBED4; ING1; ZKSCAN5; BAZ1A; CREB5; ZEB1; ZNF45; FOXJ3; WDHD1; SP3; SFMBT1; RBBP7; CNOT6; MYCBP; FOXN3; CHD7; WHSC1; SAFB2; BRCA1; MED24; HNRNPD; SNIP1; ETV4; SAP30; RNF4; BMI1; ING2; BRPF1; TLE4; MED4; HLTF; WWTR1; SREBF1; CHD1; PLAGL2; ZMYND11; TRAK1; VGLL4; TRIM32; HDAC2; SUZ12; ZNF184; ZBTB1; ZNF14; CRY1; ZNF672; RBPJ; USP21; RBBP5; PSMC3IP; ZNF3; PIAS3; KMT2A; RCOR3; TRIM24; ZNF268; ZNF248; ZFHX4; NR2F2; HOXC6; ASH2L; DPF2; RNF111; ZNF107; RBM14; PATZ1; GABPA; PARP1; TBL1X; PEX2; BACH1; MGA; MEN1; NRBF2; FOXO3; ZNF267; BTAF1; SP2; ZSCAN12; POU3F2; ZNF783; LPIN2; POU2F1; ZEB2; UIMC1; MAX; ZNF629; ZKSCAN7; ZNF23; VEZF1; APEX1; HDAC3; CCNC; PHF8; SNW1; NCOR2; KMT5A; PHF20; CARM1; ZNF516; SIX1; REST; ZBTB24; NFIB; E2F8; ZFP30; ASCL1; NRF1; ZNF506; TTF1; MAF; BRD3; ZNF212; SUB1; ORC2; ZNF443; LZTS1; GLI3; KDM5B; MLX; TERF2; HDAC6; SF1; SIX2; BATF3; ZMYND8; TAF7; NLK; PIAS1; CHD9; TAF6; BPTF; NCOA6; KDM2A; MMS19; CDK8; ZNF510; ZFP64; ZNF263; CUX1; HOXB7; BCL10; ZNF468; KLF12; ZNF536; RNF10; TADA2A; SAP18; PIAS2; NFYC; ZBTB11; ZBTB40; SMAD2; CDYL; ZNF177; MBD4; HIVEP1; RFX7; PSPC1; ARNTL2; PPARGC1A; IRF2; NKX3-1; ETV1; RNF6; DDX5; E2F3; SMAD5; RNF138; ZNF764; ZNF227; HDAC4; KDM5A; MSX1; HMGN3; ZNF236; SETD3; MLXIP; EGR1; C1D; ZNF532; TSC22D4; DNMT3B; URI1; NFIC; ZNF302; ZBTB39; TULP4; DDX17; FOXG1; CBX5; EP300; OLIG2; PTTG1; PRKDC; ATF4; NFIL3; RUNX3; PLAG1; EGR2; ARID4A; NAB1; CTNNB1; NCOR1; TAF4; BASP1; CBX3; ARID4B; THRAP3; NCOA1; ZBTB14; ID4; BAZ2B; DDX54; TLE1; HIF1A; IKZF5; TCF4; LIMD1; NFYB; ZNF384; PURA; TFCP2; ID3; ZMIZ2; MAFG; NFE2L1; EDF1; ZNF711; ATF1; ALX1; ENO1; NEDD8; THAP1; MYCN; CCNE1; TFDP2; RAN; BRF2; FLNA; HMGB3; POLR2A; EGR3; ERCC3; ZNF281; TSC22D2; YAF2; TBPL1; ZNF273; HDAC1; MYB; ELK3; SMARCC2; FOXD1; ABL1; RNF14; ZNF43; ING3; BRIP1; NRIP1; ZNF266; ZNF529; THAP10; MECP2; GATAD2A; USF2; ARID1A; TOX3; TAF1D; SMARCA2; RXRA; SMAD7; REPIN1; RREB1; CTBP2; ZMYM2; PLAGL1; TRIP6; CREB3L1; BRD2; ITGB3BP; TAF10; E2F5; SOX9; SMAD3; NR2C1; RSF1; TSC22D1; BBX; C1QBP; HEY2; SATB2; FOXC1; MTF2; ZNF217; MEOX2; SALL1; TRIM28; ZBTB38; STAT1; GTF2I; ERBB2; LEF1; SMAD1; SSBP2; MTA1