Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80756 Oxamflatin GSE92742 NPC Human 24h 10uM EID0482
Types Number Response transcription factors
Up-regulation 145 FOS; CREG1; DRAP1; PPARD; JUNB; CREB3L2; FOXO4; CDK7; SND1; LYL1; MEF2C; SIRT7; CRYM; SNAI1; PSMD9; MEF2D; KLF6; ZNF274; ZNF335; MXI1; TOB1; ERCC2; SERTAD2; ZNF205; TCEA2; CITED2; CTR9; SETD3; AIP; ECD; NFE2; NOC2L; KMT2D; ZBTB7A; CEBPE; GTF2A2; EVX1; EGR1; PCGF1; RUVBL2; ZNF212; SPIB; RBBP5; ZNF576; MBD2; NFKBIB; CEBPA; HDAC5; HHEX; KLF1; MTF1; STAT1; DBP; TCF15; ID2; FOSB; ATF6; LHX6; SP110; HMG20B; TBP; NEDD8; GATA2; KDM5A; LDB1; TFAM; OSR2; MMS19; MAX; BRD2; POU2F2; JUND; APBB1; JUN; DLX4; PIAS1; SUPT5H; YWHAB; CITED1; ZNF224; CBX6; HOXC8; ZNF556; TSC22D4; NR3C2; MAF; SIRT2; TOX4; SIX1; TRIP4; HIVEP2; ARNTL; HDAC4; ZNF410; TAF1; PEG3; SATB2; PURA; MYOD1; FOXJ1; BRF2; MLXIP; FOXC1; NAB2; PFDN5; IRF3; ATF3; TSC22D2; EDF1; ELF5; NR4A2; KLF5; SP100; GATA1; MLX; ZNF593; CCNC; FOXD1; DDIT3; NFAT5; HDAC1; MSX1; CCNT1; CREB3L1; TGFB1; TBPL1; NFIC; GATAD2A; CALR; ETS1; TCEB2; RUNX3; MNAT1; BBX; BRD4; KLF2; SOX9; SOX10; CEBPB; IRX5; HTATIP2; HEY2; RUVBL1; INSR; ELK3
Down-regulation 295 USP22; HMGA2; PCBD1; MECOM; KAT2B; PMF1; SOX11; SCMH1; TGFB1I1; CREB1; BPTF; DEK; PHF2; TP53; ADNP; ZEB1; IFI16; LIN28A; ZNF292; NCOA2; DMTF1; ZFP69B; ZHX2; HIVEP1; SOX17; NUP62; SMARCA4; TRIM22; SALL2; BCOR; ZBED1; TRIM29; HDGF; MED17; ZNF512B; NR2F6; ZNF43; PEX2; SMARCC1; PATZ1; ZNF532; ZNF22; NANOG; FOXM1; ZNF140; NFKBIA; NFYB; TAF1A; ZNF141; PRMT2; BACH1; ZNF85; BRWD1; ZNF189; ZSCAN12; HOXB9; ZFX; TTF2; HMGB2; ZMYND11; ID4; AEBP1; BRIP1; APEX1; YEATS4; ZIC1; PHIP; PRDM1; WDHD1; TSC22D3; GABPB1; ZNF32; ISL1; MEIS1; RBBP4; FUBP1; ZBED4; ZBTB3; TCF12; CTBP1; HMGN3; CHD9; CBFB; ETV4; TAF9B; BRCA2; HDAC9; CBX5; EYA1; ZFPM2; NRIP1; SOHLH2; CREBL2; SIM1; ZNF83; FOXG1; HOXB2; CENPF; TRPS1; MAML1; PITX2; YAP1; SALL1; ZIC3; THAP10; ZNF232; RSF1; CBX3; CREBZF; TBX1; CUX2; TAF9; PSIP1; ZNF84; TRAK1; PKNOX1; PLAGL2; ZFP30; PBX3; ERBB2; DDX5; HNRNPD; E2F5; ZNF711; ZBTB6; SMAD3; ZNF107; ZFP64; ZNF74; ZFY; ZNF33B; XBP1; RCOR3; ZNF468; HES1; PCGF3; ZNF623; FOXF1; VEZF1; SUPT7L; RLF; SP3; STAT6; SOX3; PRRX1; PBX1; CNBP; SOX2; RNF138; PARP1; TLE4; CAPN15; NR2C1; VGLL4; ZNF273; TFEC; FOXN3; SMARCE1; ZNF195; HIC2; BAZ1A; GMNN; BRD7; POU5F1B; NCOR1; KLF3; HOXB6; GTF2IRD1; ZEB2; ZKSCAN7; TGIF2; CLOCK; MBD4; ZZZ3; RAD21; TBL1XR1; CDK8; ETV1; CTCF; WWP1; MYBL2; TOX; YBX1; RAN; HDAC2; FOSL2; EED; TOX3; ZNF134; FOXE1; ZNF93; MEIS2; ZBTB1; LHX2; ATF1; TRIM24; ZNF423; ZNF239; PLAGL1; VPS72; BAZ2B; OLIG2; TCEA1; ZNF334; HOXD3; ARL2BP; CNOT2; ZNF529; CHD7; CHD3; KLF11; FOXF2; WHSC1; ATN1; GLI2; USP21; E2F3; SSBP3; RBM39; LEF1; CTBP2; ARID5B; AGO2; LOXL2; RBL1; TERF1; ZNF467; LZTS1; THAP1; HOXB7; GATA6; HMGB1; SMAD6; NPAS2; BCLAF1; REPIN1; RBBP8; CENPB; ASCL1; SAP30; PCGF2; TBL1X; YBX3; TP63; GTF3A; HEY1; SMARCC2; SLC2A4RG; ZNF672; DDX17; ETS2; RFX7; LITAF; NCOR2; MEOX2; NAB1; NFATC4; HMGB3; ZNF415; RBM14; BCL11A; CUX1; SOX13; ZNF131; RREB1; HIF1A; SMAD7; ZMYND8; ZBTB38; RBPMS; TCF4; ARID1A; TGIF1; TRIP6; STAT5B; HLF; MYCN; EMX2; NEUROD1; MYB; ZMIZ1; RXRA; BRD3; DACH1; ID3; ZNF217; SUPT3H; TBX3; SMAD1; HOXD1; ZMYM2; MYBL1; TWIST1; MTA1; TRIB3