Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80746 M-344 GSE92742 NPC Human 24h 10uM EID0482
Types Number Response transcription factors
Up-regulation 161 FOS; FOXO4; EGR1; CREG1; JUNB; PPARD; DRAP1; CDK7; CITED2; FOSB; CREB3L2; MEF2C; MEF2D; NR4A1; SNAI1; CTR9; RBBP5; SND1; CEBPA; RUVBL2; CRYM; STAT1; CRK; HDAC5; MYCBP; SIRT7; KLF6; NOC2L; PSMD9; NR4A2; JUN; LYL1; LHX6; SETD3; RELB; ATF3; NFIL3; BCL3; GATA2; MLXIP; DBP; MAFK; ID2; PURA; SP110; KLF2; KLF13; NCOA3; MAX; TOB1; STAT3; IRF3; TFAM; ECD; DLX4; ERCC2; MTF1; APBB1; NFKBIB; KMT2D; FOXC1; TSC22D4; NR3C2; HMG20B; CALCOCO1; ATF6; CBX6; SAFB2; ZNF593; IRX5; FOXJ1; NFAT5; EGR3; YWHAB; BBX; USP16; TGFB1; SOX10; BCL10; CDK9; HDAC1; NEDD8; ZBTB7A; SERTAD2; FOSL1; TAF12; TEAD1; SIX1; RNF10; DNAJC1; KDM5A; NR1D2; CSDE1; SMARCA2; SUPT5H; CCNC; ELF5; TSC22D2; ZNF331; PTRF; AFF1; BRD4; DDIT3; IL16; LMCD1; GTF2F1; MYOD1; UBE2B; HIPK1; KLF5; CBX7; ETS1; PIAS1; EGR4; CCNE1; TAF1; ARNTL; EPAS1; RUNX1; RUNX3; OSR2; MXI1; NFIC; MNAT1; NRBF2; HABP4; NR1H2; HIVEP2; JUND; ZBTB43; PBXIP1; TULP4; HHEX; SP100; IKZF5; RYBP; CEBPB; BRD2; SATB2; IRF7; MDM2; CREB3L1; HLTF; SPIB; WWC1; WWTR1; TAF10; MITF; HTATIP2; SSBP2; NR2F2; TBPL1; HOXA1; ERBB4; MSX1; EGR2; PEG3; SMARCD3; RUVBL1; ELK3; ID1
Down-regulation 271 SOX11; HMGA2; PCBD1; PMF1; ZNF32; ZFP36L2; MECOM; NR2F6; ZFP69B; HDGF; TGFB1I1; LIN28A; ZEB1; TP53; ADNP; APEX1; DEK; ZNF22; FOXM1; ZBED1; ZNF512B; SCMH1; SALL2; SMARCA4; YEATS2; AEBP1; KAT2B; SOX2; ZNF141; ZNF43; NCOA2; TCF12; HMGXB4; ZFPM2; ZNF423; CUX2; DMTF1; SMARCC1; ETV4; BPTF; SOX17; IFI16; ZNF532; EYA1; NFKBIA; PBX3; ZNF292; PHF2; ZNF711; ZNF682; ZNF140; YEATS4; ZHX2; TFEC; TBX1; JAK2; SETDB1; BCOR; GABPB1; CERS6; NANOG; FOXE1; ABL1; ZFY; NUP62; SOX3; ZNF93; ZIC3; ZNF85; PARP1; ZNF675; EZH2; SALL1; MED14; TAF9B; ZMYND11; TGIF2; HDAC9; ZBED4; ID4; HIVEP1; PATZ1; PRRX1; CEBPG; BRWD1; ZNF219; NFYB; HOXB6; ZNF74; MED17; TSC22D3; BRIP1; ZNF33B; PRMT2; PHIP; ERBB2; ZNF84; HMGB2; ATN1; ZNF239; ARL2BP; TFDP1; CARF; ZNF710; BRD7; MYC; TRIM22; ZNF253; PLAGL2; BACH1; CTCF; MLLT10; ZBTB6; XRCC6; ZNF232; HMGN3; RBM39; ZKSCAN7; MBD4; REL; SSRP1; ASXL1; TAF1A; TRIM29; NRIP1; NFATC4; CHD9; RLF; HOXB2; CREBL2; MYBL2; ZNF334; BCL11A; ZNF467; ZNF202; DDX17; HDAC2; ZNF180; SOHLH2; SIX2; ZNF623; RBBP4; HNRNPD; TBL1XR1; PBX1; E2F5; RSF1; MYB; RFX7; TOX3; CNOT2; BNC2; YBX3; RAN; TCF7L1; ZNF227; ZNF273; FOXF1; STAT6; TP63; FOXF2; ZNF189; SMAD3; PCGF3; DDX5; ZFP64; PITX2; RBPJ; MEIS1; WHSC1; ZIC1; THAP10; ZNF551; ZNF606; TCF3; SSBP3; GLI2; SUPT7L; CBFB; ZSCAN9; ZSCAN16; BAZ2B; ZNF134; GTF2IRD1; ZNF112; CTBP2; TLE4; TEAD4; EMX2; ASCL1; VPS72; MYCL; NCOR1; HMGB3; CNBP; TRAK1; VGLL4; LEF1; CBX5; DAXX; SP3; DACH1; CARHSP1; ZFHX3; BAZ1A; ATF1; TCF4; BCLAF1; CENPF; SAP30; CTBP1; MYCN; NR2C1; ETV1; KLF11; ARNT2; PCGF2; ZBTB1; NFE2L3; HOXB7; HOXD3; LOXL2; PLAGL1; TCEA1; HMGB1; SMAD6; RNF138; SMAD1; ZNF415; TGIF1; RXRA; PSMC3; TBL1X; NHLH2; SCAND1; ZNF107; ZNF83; ARID1A; REPIN1; GATA6; OLIG2; SLC2A4RG; E2F3; ZSCAN31; RBFOX2; HIC2; NEUROD1; ARID5B; GTF3A; FOXO1; NCOR2; BCL6; ST18; STAT5B; RREB1; PQBP1; TOX; AES; CEBPD; TFAP2A; PIR; ATF5; MEIS2; MYRF; INSM1; MEOX2; JUP; TWIST1; ZMIZ1; MTA1; TRIB3