Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80639 Plumbagin GSE92742 NPC Human 24h 10uM EID0481
Types Number Response transcription factors
Up-regulation 221 FOS; NR1H2; SPDEF; CEBPD; VENTX; TFAP2A; E4F1; NFATC4; POU4F3; IRF6; ETV3; TP73; FEZF2; ZNF215; MAML3; ZNF34; MED25; ZNF155; NR5A1; MYBL1; ZNF223; MEF2C; JUP; ACTL6B; HOXD1; E2F4; HOXB2; PRDM14; IKZF1; ZNF544; PRDM2; ZNF239; TLX2; SOX13; HNF1A; ZNF225; TRIB3; CRYM; RORA; HDAC9; NR1H4; CEBPE; POU4F2; TULP2; SOX18; IRF3; MLLT1; GBX1; RUVBL2; JUN; AHR; HSF1; LZTR1; ZNF835; NKRF; VGLL1; EMX1; POLR3C; CAMTA2; HESX1; PROP1; ZNF816; OVOL2; COPS5; ZNF345; CCNH; SPI1; BNC1; CERS4; GATA3; ZNF141; HAND1; HSF4; SOX17; PAX1; PHOX2B; AR; NKX3-2; SNAPC4; ING4; ZIC3; POU6F2; THRB; TCEA2; NPAS1; LYL1; PIR; PPP1R13L; PHF1; ZNF623; ZBTB17; HOXD3; ENY2; ELF3; ZNF180; ESR1; ATN1; HOXB1; ZNF688; EVX1; PRDM10; PRDM12; ZNF133; ZNF165; KMT2B; TAF4B; PCGF1; ZNF331; ZBED2; ATF3; ARID5A; FOXE1; ZNF415; CRX; TOX4; STAT4; TFEC; MED15; ZNF117; RING1; SUPT3H; HDAC5; ADNP2; ZNF335; BRDT; ZNF224; FLI1; HMGXB3; POU4F1; ZNF205; ZNF76; HIVEP3; ST18; CUX2; CIC; FOSB; PRPF6; FOXJ1; PIAS4; ZNF692; CDIP1; NOC2L; ARNT2; NPAS2; SHOX2; HOXC5; CBX7; MEF2D; CIR1; PNRC1; SRCAP; VDR; MKL1; MNDA; RBFOX2; HOXB5; ZNF593; ZSCAN9; ZNF444; PHIP; ISL1; TFAP2C; EHF; PAWR; TTF2; ACTL6A; TBX21; REL; LIN28A; TGFB1; CEBPB; ZNF787; WT1; HMGXB4; PSMC3; KAT5; CREB3; MED14; EN1; ZNF423; ZNF83; KAT2A; IRF7; IRF8; EMX2; TCF21; CTBP2; PBXIP1; NR4A1; HHEX; KLF4; CBFA2T3; IRF9; NFE2L3; MEIS2; MAFF; GATA1; SUPT5H; NR0B1; NANOG; DAXX; XRCC6; NR4A3; RAD21; FOXF2; GATA6; TEAD4; ZFPM2; FOXF1; CNOT3; NKX2-1; DACH1; BCL11A; YBX3; KLF6; JUNB; TRIP6; BHLHE41; NFKBIB; RUVBL1; MTA1
Down-regulation 378 KAT6A; CRK; SOX2; RHOA; SUZ12; ATF6; NCOA1; SOX4; NUP62; FOXO3; IKBKAP; ZNF24; HMGA2; ATF1; STAT3; BLM; RBBP4; ING2; PURA; BIRC2; PSPC1; RB1; TRRAP; CBX6; ZKSCAN1; LPIN2; BRD8; VEZF1; ZEB1; PSMD9; PBRM1; CHD7; MED1; SPEN; CTR9; ATF7IP; ZMYND11; BRD3; BRPF1; ZBTB24; PKNOX1; ING3; SFPQ; ETV1; SMARCA5; KMT2A; NCOA6; HEY1; GLI2; TAF1A; MLXIP; KDM2A; TCF4; BMI1; BPTF; CCNA2; ZKSCAN7; FOSL1; CHD1; BRCA1; MGA; NR2F2; ZBTB1; KMT5A; CCNT1; REST; ZNF84; ELK1; MEOX1; TSC22D1; RNF4; PHF2; STAT5B; CBX5; ZNF443; UIMC1; WHSC1; NCOR2; BCLAF1; POU3F2; ZNF148; ZBTB38; ZBTB14; ZNF419; MTF2; CENPF; TADA2A; USP22; CHD9; YWHAB; DNMT3B; ZNF282; NFATC3; ZNF248; CDYL; SMAD4; BRIP1; MECP2; RFX7; ZNF140; TRAK1; MAX; CUX1; TBL1X; NFIC; SSBP2; TGIF2; SETD2; SMAD5; ZNF586; ZZZ3; ING1; SIX2; EZH2; MLX; FOXN3; ZNF783; BAZ1B; DMTF1; KDM4A; ZNF177; BATF3; HNRNPD; ZNF200; ID3; RNF14; YAF2; ZNF211; EN2; BAZ2B; TRIM32; ZNF516; SMAD2; TP53; CREB1; YY1; RNF10; KAT7; KAT6B; KDM5B; TTF1; ZNF189; NRF1; PATZ1; HOXB9; ZNF134; SIX1; FOXO1; NPAT; DEAF1; UBP1; ID2; TCF12; SUV39H1; HDAC6; CDK8; ZNF506; NAB1; KLF5; NFIL3; URI1; ZNF672; MYCN; HMG20A; ZHX3; TAF4; DNAJC1; NFYC; POLR2A; EP400; WDHD1; FLNA; CBFB; PCGF2; CRY1; VGLL4; ADNP; MXD4; RNF111; AFF1; SMARCC2; MTDH; RAN; TLE4; MED13; RBBP5; KLF12; REPIN1; IRF2; ASH2L; PSMC3IP; MEF2A; ZFP64; THRAP3; ELF2; FOXC1; PLAGL2; PTRF; CLOCK; MSX1; TSC22D4; CITED2; NFAT5; NCOA4; MAGED1; REXO4; HOXA11; CCNE1; NFIB; THAP1; NFKBIA; GABPA; ZNF426; JARID2; BTG1; ELK3; TFDP1; RFC1; SAP30; TBL1XR1; DDX54; NFYB; PRDM4; CREBZF; LZTS1; BRF2; SOX15; OLIG2; BRD4; RNF141; PPARGC1A; ZNF131; NRBF2; ZNF281; E2F5; PIAS1; RNF6; UBE2I; BCL10; E2F2; SATB1; PBX1; NR1D2; TSC22D2; ZNF587; LIMD1; SIAH2; ZNF329; MLLT10; HOXA7; ZNF14; HEY2; HMBOX1; ZBTB11; ZNF302; LEF1; PLAG1; BCOR; CITED1; HLTF; PBX3; ASCL1; NCOR1; POU2F1; DDX5; ZNF12; ALX1; MEN1; CARHSP1; FHL2; HSF2; HIVEP2; SP140L; BBX; PIAS3; BACH1; RBM14; TEAD1; NLK; PRKDC; ZSCAN18; NEDD8; PML; FOXJ3; ZNF711; ZNF652; SETD3; SUB1; NFKB1; ZKSCAN5; GATAD2A; ID4; ZNF562; SMARCC1; KDM5A; SF1; CARM1; RXRA; ZNF468; IRF4; PREB; SIM2; TAF9B; ZNF107; ZNF430; RERE; E2F3; E2F8; MED6; ZIC1; ELF1; MEIS1; SERTAD2; PAX6; NFATC1; EDF1; TAF7; SP110; GATA4; ARID4A; TOX; FUBP1; BASP1; E2F6; RYBP; PMS1; TAF10; ATF5; MYT1L; AATF; MAF; ZEB2; HDAC1; FOXL2; ARID4B; ZNF3; MAFB; KLF7; SP3; BRD2; SMAD1; ID1; ARNTL2; NR3C2; ZNF532; SOX10; CTBP1; SALL1; PITX1; C1QBP; RUNX1; ZFP36L1; TOB1; HOXC6; RREB1; PEG3; NR1H3; TGIF1; NKX3-1; ZNF124; FOXD1; STAT1; IRX5; TGFB1I1; NR2F1; MXI1; HMGB3; CREB3L2; ZMYND8; HMGN3; EGR2; TRPS1; BATF; ARID1A; TLE1; SOX9; ZBTB18; CEBPA