Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80634 Oxamflatin GSE92742 NPC Human 24h 10uM EID0481
Types Number Response transcription factors
Up-regulation 139 FOS; CREG1; EGR1; FOXO4; FOSB; CITED2; DRAP1; SIRT7; STAT1; ERCC2; TOB1; ETS1; PPARD; CBX6; GTF2A2; SPIB; SNIP1; CTR9; JUN; CEBPE; EGR3; ATF3; ZNF593; NR4A1; SAP130; CRK; STAT3; CRYM; TBPL1; JUNB; TFAM; NR4A2; SERTAD2; IKBKAP; SND1; BRD2; CDC5L; DDIT3; SRF; PSMD9; ZNF331; RUVBL2; BRD4; BCL10; HDAC1; LYL1; BRF2; HOXD1; PPP1R13L; LMCD1; MED23; CALCOCO1; UBE2B; PIAS1; APBB1; TCF15; NCOA3; MYCBP; RBBP5; NPAS2; FOXC1; CBX7; ZBTB7A; ZNF224; MEF2D; CREB3L1; IRF7; NR4A3; CDK7; KLF2; MTF1; ELF3; ZNF394; TSC22D4; ZNF556; ECD; ZNF267; NR3C2; SAFB2; BHLHE41; BCL3; SETD3; GTF2F1; ZNF205; LHX6; KLF10; KLF6; TGFB1; TAF10; NEDD8; EPAS1; DLX4; SUPT5H; HTATIP2; HOXA1; HHEX; ITGB3BP; IRF3; JUND; GATAD2A; ADNP2; SATB2; SUPT4H1; OSR2; ERBB4; NFIC; YWHAB; HMG20B; SMARCA2; ARNT2; HIVEP2; OVOL2; DBP; IRF6; CREB3L2; PBXIP1; TRIB3; NOC2L; KLF5; SOX10; VDR; ZBTB43; RUNX3; INSR; BBX; SIX1; EHF; MLXIP; HLTF; SNAI2; MXI1; IRF8; NFE2; SREBF1; MNAT1; EGR2; CEBPB; MSX1; HOXC10
Down-regulation 266 SOX11; ERBB2; TP53; SMARCA4; ZNF43; ZMIZ1; SOX2; MYCN; NUP62; BAZ2B; ZKSCAN7; PCBD1; HMGA2; PAXBP1; HNRNPD; GLI2; GABPB1; DDX17; LIN28A; HDGF; ZNF282; TCF4; SCMH1; TCERG1; HOXB2; ETV1; TAF9B; FOXM1; WHSC1; ZNF532; NR2F6; NFKBIA; ZEB1; ADNP; CTCF; ZNF711; GTF3A; SMAD3; DEK; ZSCAN31; KAT2B; BTF3; DMTF1; ZNF253; CARHSP1; ZMYND11; ZHX2; PARP1; TCF7L1; ZNF292; HDAC2; MEIS1; SALL1; CBFB; BPTF; PATZ1; LZTS1; RBBP4; ZIC3; NHLH2; CNBP; SALL2; ZNF232; ZBED1; RAN; ATN1; CUX2; BRIP1; PMF1; ZBTB6; STAT5B; ZNF512B; GTF2IRD1; DPF2; USP22; CBX5; ZNF141; NCOA2; ZFP69B; PBX3; NONO; DDX5; ZNF22; PKNOX1; RFX7; EYA1; BRWD1; SOHLH2; ZNF32; CREB1; ZNF84; PHF2; ZNF93; ZNF227; EZH2; NEUROD1; ZNF783; TGFB1I1; MLLT10; ABL1; ZNF177; ZNF334; NCOR2; ZNF675; NFE2L1; TAF1A; ZFY; PLAGL2; ZNF85; XBP1; TGIF2; TCF12; ZNF248; ID4; MBD4; FOXF1; CNOT2; ZNF219; NFKB1; BCL11A; HMGB1; ISL1; CDK8; HMGN3; APEX1; TRIM24; ZNF202; PCGF3; CTBP1; LHX2; TBL1X; ZNF672; DEAF1; LEF1; GTF2I; RBM39; OLIG2; PBRM1; TLE4; ZBTB38; YBX1; HIPK3; RXRG; ZNF140; HMGB2; CHD3; ZMYM2; ASCL1; E2F5; BAZ1A; SMARCA5; PRMT2; MECOM; ZNF134; ZNF423; YEATS2; ZFP64; HMGB3; PBX1; TSC22D3; REPIN1; RBM14; ZNF83; BRD3; ZNF239; ZNF273; IFI16; ASXL1; SMARCE1; ZNF623; BCL6; CENPF; VGLL4; TSC22D1; YAF2; HEY1; BCOR; ZNF189; FOXN3; BCLAF1; SMARCC1; PLAGL1; WDR77; MYBL2; ZNF146; ZNF529; BMI1; SOX5; NKX2-2; SETDB1; LOXL2; NRIP1; SMAD1; CHD9; KAT5; SSRP1; CAPN15; PITX2; FOXG1; ZNF302; SUV39H1; TBL1XR1; PQBP1; ZNF107; NAB1; RBPJ; MED16; ZIC1; SP3; ZFP36L2; KAT6B; SIX2; PAX6; SOX17; HIVEP1; ZBTB1; NANOG; CREBZF; TOX; TRIM22; MEOX2; SAP30; ZNF516; MED17; DLX2; SLC2A4RG; FHL2; BACH1; TWIST1; FOXO1; RBFOX2; CHD7; TOX3; DACH1; NPM1; RXRA; AEBP1; RSF1; MAGED1; FOXF2; SIAH2; ZFX; AES; GATA6; ZNF652; GRHL2; CBX3; TFDP1; CREBL2; E2F3; HOXB6; ZFHX4; PRRX1; SMAD6; NKX2-1; ZFPM2; ZMYND8; DLX5; MEIS2; TGIF1; DAXX; INSM1; ENO1; NR2F1; MYB; MTA1