Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID80629	Nvp-bez235	GSE92742	NPC	Human	24h	10uM	EID0481

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	FOXO4; FOXO3; ZNF358; DDIT3; TCEA2; JUN; HOXB2; KDM5C; TCF7L1; BAZ2B; ETS1; CEBPE; CEBPD; PCGF1; MXI1; ZNF671; KDM5B; CITED2; RFXANK; HDAC5; TRIB3; PNRC1; ZNF83; LITAF; ZNF91; APBB1; NFE2L1; NKX2-2; KMT2B; DPF2; RXRB; NFE2; RYBP; MYC; PPP1R13L; ZNF211; PFDN5; MZF1; SIRT2; BACH2; PBX2; MEF2D; LOXL2; COPS2; PHF1; ATF4; MNDA; SETDB1; TEAD3; ZNF444; BTG1; KLF6; CEBPB; KAT2A; MAFF; BCL11A; ZBTB7A; TCF25; ZNF117; ZNF264; IRF9; JUND; BRD2; SUPT5H; ST18; BRD4; MAFB; CALR; ZNF165; SND1; BACH1; ZNF580; GTF2F1; STAT6; TCF7L2; CREB3L2; HBP1; VGLL4; SERTAD2; GFI1; FLNA; TGFB1I1; AFF1; MYRF; CHD7; INSR; ARID4B; HHEX; CDK7; TLE4; ATF3; YBX3; JUP; SNAI2; SOX9; TBL1X; WT1; ARID1A; PEG3; TLE1; MTA1
Down-regulation	110	KDM5D; GMNN; SFPQ; ATF1; ING2; CCNA2; RB1; SUZ12; CDK2; NUP62; RAN; CREB1; BLM; EZH2; TAF1A; MYCBP; MYBL2; RBBP8; USP22; HSBP1; E2F2; MECOM; GTF2A2; PSMC3IP; TFCP2L1; BRCA1; WDHD1; ZNF468; PPARGC1A; ZNF672; ETV1; PLAGL2; CBFB; CENPF; TAF9; PARP1; TERF2; ASH2L; MED21; TTF2; RNF14; NR4A1; ZMYND11; SUMO1; XRCC6; SSBP2; TBX3; ARL2BP; BRIP1; RBBP4; ZNF443; SMAD5; WDR77; HMGB1; WWTR1; ZBTB38; DNMT1; MECP2; YEATS4; NFYB; FOXM1; THAP10; ID3; PIAS2; HNRNPD; HMGA2; ESRRG; MYBL1; SUV39H1; HLTF; ENY2; NR3C2; TFDP1; ACTL6A; RNF138; E2F8; ITGB3BP; BATF3; NRIP1; KLF11; TOX; FOXF1; MBD2; DNAJC2; DR1; CREM; HMGN3; ERBB4; PRRX1; EED; ZNF331; CBX3; ARNTL2; TRIM22; RUVBL1; STAT1; NR1D2; ETS2; HMGB2; NFIB; CCNE1; TOB1; HEY1; NR2F1; DAXX; MNAT1; NKX3-1; ZFPM2; ID1; BHLHE41