Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID80579	Bix-01294	GSE92742	NPC	Human	24h	10uM	EID0481

Response Information :

Types	Number	Response transcription factors
Up-regulation	384	MEF2C; FOS; CEBPD; NR1H2; PRDM2; TP73; REL; KLF4; JUN; SOX18; NFE2L2; SPDEF; TFAP2A; IRF6; FEZF2; SSX1; PRDM10; ZNF34; HDAC9; ZNF467; HHEX; ZNF350; ZNF345; ESR1; CARF; HIPK1; SCAI; ARID5B; NR1H4; ZNF225; SOX14; EMX1; ERBB4; ZNF83; ZNF331; ZNF257; ZNF682; NKRF; ZHX2; PNRC1; POU4F3; SKIL; LYL1; DDIT3; TRIB3; POU4F1; JUP; HOXD1; THRB; E2F4; PHIP; ZNF623; TULP2; ZNF215; SP100; ZNF10; NR0B2; CCNH; SNAPC4; WWP1; SOX17; ZNF195; ZNF154; ZNF222; TRIM33; IRF9; TBX1; PIAS1; ZNF85; NEUROD2; ZNF254; ST18; CSDC2; PRDM9; ZFP2; VENTX; BAZ2A; E4F1; HINFP; ZNF250; NR4A3; CIR1; FOXE1; MXI1; AHR; MLLT1; NR4A2; CAMTA1; ZNF217; ETV3; ETV2; HDAC5; ZNF91; ZNF415; ZNF174; ZNF695; NR5A1; TULP1; ZNF557; POU6F2; ZNF180; ZXDB; NFATC4; ACTL6B; EGR1; L3MBTL1; ZNF43; ZNF701; ZNF214; ETS1; SCRT1; ATF2; MNDA; ZNF107; ZNF224; NFKBIA; GATA6; ZNF135; FOXB1; ZSCAN31; FOXH1; SOX13; ATF3; TAF4B; MKL1; ZNF394; BTAF1; EMX2; OSR2; ZNF611; TRIP11; POU1F1; TWIST1; ZNF155; PAWR; JUNB; ZNF816; RSF1; CEBPG; TGFB1; TCF7L2; TAF9; FLI1; NEUROG2; SIX6; ZNF223; ZNF391; IFI16; SHOX2; ZNF492; MYEF2; POU2F3; FOSB; ARID3A; HOXB1; MAK; FOXA2; LHX6; HOXB2; ZNF675; EN1; TRIM22; TSHZ2; SOHLH2; ZNF354A; JAK2; PAX4; HBP1; ARNTL; TBR1; HNF4G; BRWD1; BRD2; RFX1; MED17; ETV6; ABL1; OVOL2; ZNF165; VGLL1; GSC2; ZNF117; SUPT7L; ATN1; PSMD9; IRF7; TFAP2C; NCOA2; BCL11A; CDC5L; DACH1; SATB2; HESX1; TAF5; CREM; RORB; ZNF141; NR5A2; SUPT3H; POLR3C; NEUROD6; ZNF235; ZFPM2; KAT8; BRDT; IKZF5; ZNF44; NR0B1; ZIC3; PEG3; SNAI2; ZBTB3; CDIP1; TAF1C; TFDP3; CCDC59; ZNF335; HLX; ZNF74; NFE2; SRY; ZNF253; RELB; CHD2; KLF7; POLR3F; MED23; VDR; AFF4; ELF4; GCM2; ZKSCAN4; CERS6; ZNF136; NPAS2; CCNT1; ZNF440; MYBL1; RYBP; NEUROD1; CERS4; TERF2; ELK4; KLF9; BHLHE41; ZNF667; MDM4; HOXD3; ZNF654; LHX1; CNOT3; CBX7; RAD21; NFE2L3; PRDM1; ZNF665; LHX2; ZNF304; KLF11; ELF3; HIC2; CAMTA2; ZNF239; EHF; SRCAP; WT1; FOXA1; SIN3B; ZNF573; TOPORS; COPS2; DNAJC2; CBFA2T2; TRIM24; HOXD13; SP140L; ZNF544; CHD1; STAT1; RRN3; CITED2; CEBPB; NFYA; ZSCAN9; BACH1; CBX4; ARNT2; EPAS1; ZEB1; MDM2; SUPT4H1; BACH2; KLF6; MYNN; KAT2B; KLF3; MED15; CBFA2T3; ERG; ZNF688; UBE2B; SSBP3; SOX21; ZNF175; ZFP36L2; CDX1; ZNF571; ZXDC; NR3C2; ATOH1; ZNF444; PBXIP1; CRYM; TRPS1; ASXL1; RORA; TAF5L; ANKRD1; RBM39; AR; PCGF1; ZNF160; FOXF2; ZZZ3; ZBTB43; BTG1; TAF11; ZNF430; CDK7; MED13; NR2C1; PPP1R13L; ARID5A; ZFHX3; ZNF184; BRD4; BCL6; CD3D; BAZ1A; MEIS2; KLF13; TEAD4; TFEC; TCF7; ATF7IP; HIRA; ZNF721; GFI1; TAL1; IRF8; RING1; HLF; ZFX; ZNF124; HIVEP1; ZNF189; MAFF; SMARCA2; ZNF264; PROX1; ARID4B; HTATIP2; HOXB13; INSR; NRIP1; ZBTB38; IRF1; GATA2; ZBED2; ARID1A; DLX5; MYRF; EGR4; MSX1; KDM4C; YBX3; CALR; EYA2; NR4A1; RREB1; POU2AF1; MYB; INSM1; AEBP1
Down-regulation	370	ERBB2; NUP62; RBBP4; CCNA2; PARP1; SMARCA4; TP53; RHOA; PUF60; BRD8; EZH2; BRPF1; PSIP1; HNRNPD; UBE2I; DNMT3B; ZKSCAN7; WHSC1; GTF2IRD1; ING2; TBP; NELFB; SMARCE1; KAT7; ZNF358; MAGED1; RBBP7; STAT3; CBX5; TRRAP; RFX5; TCF7L1; CENPF; HMGA2; BRCA1; GLI2; NCOR2; BCLAF1; SMARCA5; XBP1; ZNF672; ZNF24; RNF4; SUV39H1; PSMC3IP; NEDD8; SIX2; THAP11; CBFB; BRD3; YBX1; WDHD1; STAT5B; ZNF45; NONO; DDX54; TBX2; ATF1; HDAC6; NFATC3; PCGF2; ELK1; SOX11; HDAC2; ZMIZ2; BIRC2; RBM14; TADA3; PKNOX1; ZNF783; HDAC1; LPIN2; USF2; HMGB3; BASP1; SSRP1; ZBTB1; ZBTB24; EDF1; MYCBP; RAN; TBL1X; KDM5D; SMAD2; HMG20A; ZNF446; PIAS2; USP22; ZNF423; BLM; SNW1; MDFI; PIAS3; NFRKB; TSC22D4; FLNA; SMARCD1; ETV1; BATF3; CDYL; DNAJC1; E2F5; PRKDC; EWSR1; LIMD1; ECD; BMI1; BAZ1B; MLX; SND1; HSBP1; TRIM28; CASZ1; UBP1; CHAF1B; ETV4; KDM4A; PATZ1; SP110; ID3; TRIM32; PMF1; MYCN; TADA2A; ERCC2; LITAF; ETV5; PTTG1; EYA1; MXD3; KDM2A; ZMIZ1; UBE2L3; ID4; POLR2A; WWC1; ZMYND11; SMARCD2; NPAT; CENPB; MAX; CARM1; LZTS1; SP2; ZSCAN5A; REPIN1; ING3; DRAP1; CREG1; PBRM1; URI1; NFYC; TAF9B; SSBP2; TGFB1I1; USP21; ZNF629; RNF141; VAX2; ALX1; FOXC1; DEK; BRD7; ZNF528; MTF1; SUZ12; ZFHX4; RUVBL2; HMGN3; KLF12; TLE4; HLTF; NR2F6; RERE; CARHSP1; CBX3; ZNF226; SF1; CBX6; EP400; BRIP1; PHF2; ENO1; DDX5; SETD3; HDAC3; ADRB2; HCFC1; ASCL1; NRBF2; SAP30; ZFP64; RBL1; NCOA4; SMAD3; HES1; SMARCD3; CREB1; SMARCC1; E2F3; POU3F2; ZNF419; E2F6; ZHX3; MED16; POU5F1B; GTF2A2; ZNF282; PPARGC1A; ZNF134; NR2F2; TFAP4; HR; ZBED1; CTR9; PBX1; ZNF32; TRIM27; ZNF302; PSPC1; RFX7; ID1; WIZ; ORC2; C1QBP; ZNF443; PREB; MTDH; PQBP1; SALL2; FOXJ3; PITX2; TSC22D1; KLF10; GABPA; RBBP5; PTRF; JARID2; ELK3; ASH2L; PHF20; TAF10; ZIC1; E2F1; NRF1; ZNF248; MLLT10; ZNF22; UBE3A; NCOA1; KAT6B; ATF4; SOX10; PBX3; HSF2; IRX5; ZBTB14; SIX1; TCF12; PHF8; REST; ESR2; RBBP8; TRIM29; SREBF1; MEIS1; MED24; ZNF84; ISL1; SUB1; EED; MXD4; CXXC1; ZNF146; SREBF2; MSC; PDLIM1; IRF2; C1D; CITED1; ING1; CTNNB1; HOXB9; CCNE1; MNT; ZNF3; RXRA; CHD7; NKX2-2; APEX1; KLF5; RBPJ; PURA; NR2F1; SCMH1; YWHAB; SMAD6; MMS19; RB1; ZNF266; CNBP; ZFP36L1; TRIM16; CREB3L1; MEOX1; RNF14; SMAD5; SMARCA1; CNOT1; TFDP1; RBPMS; TCF4; FHL2; TAF7; NAB1; ZBTB18; ZBED4; PKNOX2; TAF6; TSG101; TOX; ZEB2; SCAND1; MED6; PEX2; EHMT2; ETS2; KMT2A; FOXF1; MAF; MBD2; RNF111; BCL11B; NPM1; BCOR; SMAD7; ADNP; ARID4A; NFIB; TBL1XR1; HMGB2; MLXIPL; VGLL4; SIM2; ZNF580; ZNF410; HOXC6; MED1; MEOX2; GATAD2A; KMT2D; CTBP1; LOXL2; KLF2; BBX; TEAD1; HEY1; ZMYND8; TOX3; ZSCAN18; RCOR1; ARNTL2; ZNF131; MNAT1; HMG20B; RUVBL1; TRIP6; HOXB7; SOX9; CEBPA