Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80512 Plumbagin GSE92742 NEU Human 6h 10uM EID0480
Types Number Response transcription factors
Up-regulation 150 IRF9; CCNH; E2F4; ATF3; MED25; ZNF239; SUMO1; MED21; ACTL6B; ZNF671; CALR; TBX21; TP73; LZTR1; TBX5; ZNF195; ZNF232; KAT2B; PRDM12; NFATC4; ZNF117; YEATS4; ZNF215; NFATC3; NFKBIB; KLF6; BARX1; PAWR; PBXIP1; SRY; ETS1; TUB; SOX21; HOXB1; IRF6; DDIT3; SUPT3H; THRB; TTF2; AR; MYBL2; ZNF335; HOXB2; GATA6; E4F1; ACTL6A; TFAP2A; HOXA3; PRDM14; CEBPD; HDAC9; KAT2A; ZNF576; THAP7; PBX3; CERS4; SOX13; SPDEF; HSF4; CEBPE; ZIC3; AIRE; EPAS1; ZNF771; MED15; CDK2; FOXE1; PNRC1; TCF7L2; SNAPC4; RORC; CRYM; TBX3; SIX6; PIR; VGLL1; HSF1; HOXC8; TCF21; CREB3; BLZF1; WT1; ZNF544; HOXA6; NR5A2; ZFP36L1; TAL1; ITGB3BP; ZBED2; FOXH1; HIRA; CDX1; CDC5L; WWP1; LIN28A; WDR77; TFCP2; CDIP1; TEAD4; CNOT3; NFE2L3; GATA1; KLF13; NFE2L2; RFXANK; HOXA5; TULP3; ZNF593; TRIP11; MXI1; PSMC3; BNC2; RAD21; CREBL2; CSDE1; TRIB3; MED12; YAP1; SP100; STAT4; NKX2-1; CEBPB; MYBL1; RB1; IFI16; MEIS2; ATF5; AEBP1; GFI1B; ARNTL2; IRF1; YBX3; CD3D; STAT1; VDR; NR0B1; HOXD1; DAXX; SPIB; ZBTB20; CREB3L2; OVOL2; TERF1; HOXB6; FOXA2; ESR1; NANOG; CITED2; ARID5B; MYCBP
Down-regulation 326 SOX4; BASP1; KAT6A; FOXO3; ARID4B; ZMIZ1; MTF2; NUP62; CRK; PBRM1; KDM5B; ARID4A; NRIP1; MAGED1; PHF2; ZMYND11; JARID2; ZMYM2; ZNF146; SETD2; HNRNPD; NRF1; MED23; ZNF672; REPIN1; ING3; BBX; BAZ2B; NCOA1; TBP; EP400; ZEB2; BMI1; BCOR; TCERG1; BRPF1; SNW1; BTAF1; TRRAP; LPIN2; BCLAF1; SFPQ; CDYL; WHSC1; NCOA6; SMARCE1; RNF4; LIMD1; CTR9; BRD8; ADNP; ZNF3; EN2; RNF111; CRY1; NFATC1; SUV39H1; USF2; KDM2A; SMARCC1; TRAK1; ZHX3; EP300; PATZ1; HMG20A; TLE4; ZNF248; ZNF324; ZBTB24; MECP2; MNT; TRIM28; TBL1X; ZKSCAN7; VGLL4; ZNF14; ERBB2; MAX; KAT6B; FOXO1; ASH2L; ID2; POU3F2; ZNF302; HSF2; ARID1A; ZNF236; CHD1; ZNF443; ZBTB14; MLXIP; HLTF; HEY2; LZTS1; NCOR2; DPF2; NCOA4; ZNF282; RCOR1; BRD3; BAZ1B; POLR2A; ATF1; MED1; NRBF2; TCF4; RBBP4; SPEN; BRF2; KMT2A; SOX2; FUBP1; ZNF189; UBP1; ZNF430; DDX54; BACH2; SETD3; PHF8; SIX1; BRD4; RHOA; MYCN; FOXO4; IL16; BATF; CREBZF; PPARGC1A; ZNF184; ZNF783; NFIL3; VEZF1; SUZ12; ZNF536; RBM14; TULP4; BPTF; RBPJ; NHLH2; ZNF24; KMT5A; FOXN3; MLX; PIAS2; HIVEP2; RFX7; SMAD4; ZNF419; ZBTB1; ZNF629; DDX5; KDM4A; KAT7; DNMT3B; SMAD2; NAB1; POU2F1; MGA; ZIC1; PURA; ORC2; ZKSCAN1; NONO; ZNF211; TSC22D2; CHD7; EMX2; CBX5; ZNF468; CHD9; MYT1L; ELK1; TBL1XR1; ATF7IP; MTA1; CCNA2; TGIF2; ZNF292; ZNF516; ING1; AFF1; KLF5; NCOR1; ZSCAN16; ZBTB18; ETV1; SATB2; HEY1; ZBTB40; ING2; TMF1; TADA2A; ELK3; ZNF764; NPAT; MED24; SNIP1; YWHAB; NFIB; MSX1; CUX1; LHX2; NFKBIA; EGR3; ZEB1; NCOA3; AATF; SP3; ESRRG; SIAH2; LEF1; PKNOX1; NR2F2; SATB1; GABPB1; CBFB; BCL10; PLAGL2; CDK8; DDX17; TTF1; PCGF2; NR1D2; XBP1; ZFP64; ZNF532; ZFP36L2; MEF2A; SF1; FOXC1; ALX1; BIRC2; NLK; RUNX3; TRIM32; CBX3; REST; OLIG2; RREB1; EZH2; TSC22D1; FOXJ3; SMAD5; MAF; BCL11B; CLOCK; ZNF529; ZNF84; PAXBP1; ZNF281; PREB; SIM2; TP53; RBBP7; TLE1; ZMYND8; MED13; SMAD7; RYBP; KDM5A; HDAC6; ZNF107; MAZ; PCGF3; TAF4; EGR2; HOXC6; NFAT5; MITF; SFMBT1; IRF2; BAZ1A; YBX1; SMARCA2; SMARCD3; SSBP2; CENPF; ID4; PBX1; INSR; ERG; ZBTB38; EYA1; SMARCA5; DLX5; RNF6; MYC; DNAJC1; ZNF587; SMAD1; PLAG1; HMGA2; TCF12; IRX5; NR3C2; ZNF721; CHD3; ZNF131; HMGB3; RERE; PRKDC; HDAC1; ZNF160; WWC1; ETS2; HMGB1; ZBTB16; MED6; JUND; IRF4; ASCL1; ZNF267; ZNF652; MYB; FOXG1; IKBKAP; EYA2; CCNE1; HOXB7; TRIM29; FLNA; SERTAD2; RFX5; MEIS1; SMAD3; DACH1