Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80374 Oxamflatin GSE92742 NEU Human 6h 10uM EID0479
Types Number Response transcription factors
Up-regulation 121 CREG1; PPARD; RUVBL1; HMG20B; NFE2L2; STAT3; NOC2L; PURA; CTR9; ING2; SETD3; RNF6; ZNF593; DRAP1; TXNIP; RBBP5; TOB1; ING1; AFF1; RUVBL2; ZNF324; SIRT7; CRY1; CRK; UBE2B; MLX; MEN1; ESRRA; PMS1; TAF12; IRF3; TRIM32; DNAJC1; AHR; HLTF; TCFL5; MYCBP; TAF10; SPIB; SAFB2; JUNB; FOXO4; WWC1; BCL3; NR4A2; ZBTB11; SATB2; ZMIZ2; DBP; ELF1; BBX; HTATIP2; NR3C2; HDAC1; SREBF1; TBP; POU2F2; MSX1; AATF; FOSB; PSMC3IP; MLXIP; OSR2; FOXJ1; KLF2; TFAM; NKX3-1; MAX; HLF; TOPORS; RUNX3; SND1; NRBF2; RNF4; BMI1; NEDD8; TGIF1; TSC22D4; HSF2; TRIP6; BRD4; ZBTB18; EDF1; ARID4A; SUPT4H1; HMGA1; CITED2; YWHAB; ZNF331; NR1H3; IRX5; SSX1; KLF5; TRIM28; IRF7; ZNF281; CDK2; PHF1; RBL2; TSC22D2; BIRC2; CREM; ITGB3BP; KDM2A; SIX1; EGR3; ENO1; YBX1; ARID5B; MXI1; HOXC6; TSC22D1; CALR; PTTG1; HDAC6; KDM5A; ZNF131; TBPL1; NFIB; FLNA; BASP1
Down-regulation 148 MEIS2; TRIB3; ZNF91; BAZ2B; ZNF710; SMARCC1; PHF2; SIX3; CTCF; SCMH1; PMF1; LIN28A; NCOA2; CAMTA1; BCL11A; PRDM10; FOXM1; RAD21; KLF3; ZIC3; ZNF140; ZNF253; BPTF; ZNF337; HOXB5; ZNF74; UBE2I; ZNF32; KAT6B; LHX2; PROX1; ZNF665; FOXA2; ZNF623; HEY1; BARX1; SOX21; ZNF43; OVOL2; ZBED1; NHLH2; ZNF33B; DACH1; PNRC1; FOXE1; SETDB1; ID4; HOXB2; HOXB6; TOX; EN1; ZNF532; CUX2; PBX3; INSM1; HIPK2; ZFP69B; CUX1; CDIP1; CNOT6; BNC1; ZNF117; AFF2; ISL1; SMAD4; ZNF180; ST18; JAK2; ZMYND11; SALL1; RSF1; GRHL2; RARB; ADNP; HDAC9; ZMYM2; MYBL2; SALL2; MAML1; SMARCA4; BCL6; AGO2; RAN; ZNF85; CITED1; HIRA; FOXG1; MNDA; CTBP1; TBX1; NCOR2; SOX13; NANOG; NFE2L3; SOX17; TCF7L1; GTF2I; SIX2; ZHX2; HDGF; ARNTL2; TWIST1; TAL1; ATN1; KLF7; SUPT3H; TFDP2; DLX5; RBFOX2; MED13; ELK4; FOXF2; CTBP2; INSR; EYA1; ERBB4; ZFP36L2; SNAI2; TRIM29; IRF6; ASCL1; MKL2; AEBP1; HMGB3; SHOX2; ZFP36L1; STAT6; FLI1; VPS72; ETS1; NR1H2; MYRF; GATA6; TRIM22; TCF4; MECOM; LEF1; ERBB2; MEOX2; PRRX1; BNC2; NR2F6; ID1; ZNF232; ZBTB38; JUP; PIR; IFI16