Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80289 Diaminoquinazoline GSE92742 NEU Human 6h 10uM EID0479
Types Number Response transcription factors
Up-regulation 93 EGR1; JUNB; FOS; KLF9; ZNF415; CBX4; VGLL1; PNRC1; NR4A3; TAL1; NR4A2; ATF3; SNAI2; TFAP2A; CEBPB; KLF3; ZNF165; IRF4; BARX1; RB1; HMBOX1; TTF2; CEBPD; HOXB5; ACTL6A; IRF6; IRF9; MAFF; ETS1; YEATS4; JUN; SKIL; PEG3; KLF7; TGFB1; TULP3; TRPS1; FOSB; DACH1; FOXG1; SOX17; KLF6; ZNF331; SPDEF; HOXD1; NFATC4; MYC; CREB3L2; NR5A2; ZNF232; HDAC9; ARNTL; ZNF589; ZBTB16; TWIST1; ZNF117; TBX3; AR; CREBL2; BRD4; FOXL2; TCF21; PIR; BNC2; ZBTB38; NR4A1; PGR; GATA6; PTRF; CDK2; HOXB2; RUNX3; IFI16; CBFA2T3; RUNX1; ZBED2; PAWR; AEBP1; NR2F6; ZNF394; ELF5; NR0B1; FOXA1; VPS72; ELF3; ESR1; EGR2; EHF; ATF5; POU2AF1; CREB1; EGR3; RBPMS
Down-regulation 131 NCOA4; KDM5D; EZH2; BAZ2B; BRD8; TCEB2; EDF1; PSIP1; ZNF212; USF2; HSF2; CREG1; VGLL4; CARHSP1; ZNF528; NKX3-2; KMT2A; KAT5; NRF1; WWC1; ZNF7; ZBTB18; RBBP4; ZNF211; REXO4; SNIP1; MED6; JARID2; PATZ1; NHLH2; CITED2; FUBP1; KAT7; FOXJ3; BASP1; SETD2; CENPB; NFYC; HSF1; HDAC7; ZMIZ2; ZNF443; ZNF552; PCGF2; MGA; NAB1; RLF; RBM14; CBX5; CHD3; SMARCD3; SF1; BTAF1; PSPC1; NELFB; EYA1; KAT6A; TBP; DNMT3B; SNW1; TBL1XR1; ELK1; AFF1; ZBTB24; ARID4A; HMG20B; ATF1; SMARCA4; TLE4; CTR9; IRF7; HNRNPD; ZMYM2; ID3; OLIG2; ERBB2; BRD3; ID2; SALL1; ZNF672; PA2G4; MAGED1; LPIN2; NPM1; VEZF1; MED24; CHD7; NUP62; TRIM28; NFIB; CCNC; SATB1; TCF15; ENO1; CCNA2; RBPJ; BCL11B; NR2F2; NEDD8; CTNNB1; MYT1L; MAZ; TAF10; SMAD1; HDAC1; SSX1; CENPF; RXRA; KDM5B; TBL1X; DRAP1; ZNF281; SATB2; HMGN3; BMI1; MYCN; TP53; HDAC6; NCOA6; SIX2; ZHX2; HLTF; PTTG1; SMARCA5; RERE; LEF1; HMGA1; YWHAB; SCAND1; MYCBP; MAFB