Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80254 Pyrvinium GSE92742 NEU Human 6h 10uM EID0478
Types Number Response transcription factors
Up-regulation 75 MNAT1; FOS; NFKBIA; KAT6B; HDAC2; KDM5A; SIX1; ENO1; KDM2A; KAT2B; ING3; DNAJC1; RBM14; NCOR1; RCOR1; FOXO4; HMGB3; TRIM28; SMARCA4; NKX2-1; SNW1; HOXA11; ZNF426; IRX5; BAZ2B; BRD7; ZNF516; SALL2; MYB; ZNF177; TCF12; CDYL; AATF; ATF4; BATF3; CREB3L1; SMAD6; BAZ1B; ZNF45; FLNA; BASP1; CDK8; VGLL4; ZBTB1; ZFHX4; EDF1; YAP1; CUX1; MED6; KLF5; AIP; MEF2A; BATF; ZNF22; EMX2; DPF2; ZNF423; RUNX3; PAX5; FOXJ3; SCAND1; DRAP1; TRIP6; JARID2; EP300; ZNF281; ZEB1; CHD7; NR1D2; DACH1; ZBTB20; MTA1; HMGN3; ABL1; MTF2
Down-regulation 62 TFAP2C; LHX6; RNF138; ZNF331; GTF3A; MYC; HOXB13; NKX3-1; ZNF83; KLF3; ACTL6A; MYNN; ZNF415; FOXF2; EN1; FUBP1; FOXE1; ZNF24; KLF10; CCNH; SNAI2; ZZZ3; ZBTB18; EHF; SMAD1; TBL1XR1; E2F8; SSX1; KLF2; INSM1; DLX5; MYBL2; PNRC1; POU4F1; NEUROD1; IFI16; ELK4; TRPS1; KLF9; KLF4; HHEX; IRF6; TFAP2A; PURA; FOXG1; BCL3; NFE2L2; ZFPM2; ZFP36L2; MYCL; JUP; ID4; HLF; IKBKAP; HEY1; TRIM29; SOX9; ARID5B; HOXD1; EGR3; HOXB2; CEBPB