Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80159 Diaminoquinazoline GSE92742 NEU Human 6h 10uM EID0478
Types Number Response transcription factors
Up-regulation 42 FOS; NFKBIA; IRF4; MYC; FOXO3; ATF4; ZNF516; ZFP36L2; WHSC1; ATF6; FLNA; BTG1; DDIT3; NKX2-2; POU2AF1; E2F8; SSBP2; TP63; TBX3; TWIST1; FOXN3; VPS72; CEBPD; HDAC9; CEBPB; HOXB6; LMCD1; ST18; MSX1; KLF5; KLF6; MYCL; TFAP2C; PBX1; NFE2; SNAI2; IRF6; SOX2; ID1; HOXB2; ATF3; PEG3
Down-regulation 34 FUBP1; MKL2; BRD8; TADA3; ZNF14; ZNF45; SMARCA4; ZZZ3; MAF; PATZ1; WWC1; ZNF629; SFPQ; NR2F2; NFIB; SUB1; HDAC1; C1D; ZNF226; ZMYM2; ZNF12; ERBB2; SMAD2; PSIP1; HMGB2; YWHAB; TRIM22; HLF; ZBTB18; ZMYND8; PLAGL1; HMGN3; IKBKAP; MAFB