Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80151 Pyridine-2,4-dicarboxylic-acid GSE92742 NEU Human 6h 10uM EID0478
Types Number Response transcription factors
Up-regulation 121 AFF1; TBP; TLE4; TP53; PARP1; CTR9; ZKSCAN7; SMARCC1; TCERG1; FOXO1; RFX7; HDAC2; GABPB1; MED1; BAZ2B; SNW1; MED23; ZNF516; IL16; RCOR1; HSF2; FOXO3; KDM5B; ARID4A; PCGF2; ZNF274; RBM14; ZNF587; MYCN; TBL1X; ZNF426; ZNF532; SMARCE1; DEAF1; FLNA; SAFB2; ZNF292; MED24; ZNF358; ALX1; MLLT10; SMAD4; ENO1; CITED2; MAZ; CHD7; ZNF93; ZNF551; L3MBTL1; PBX1; ZNF177; PRKDC; SMARCA4; SATB2; AATF; TRRAP; KDM2A; NHLH2; WWC1; TAF10; PAX5; MYT1L; RBBP4; MSX1; KAT7; HDAC6; SALL2; ADNP; ZNF711; RUNX3; BATF; NCOR2; TULP4; RREB1; RCOR3; CARM1; HLX; ID2; BCOR; MGA; PATZ1; TSC22D2; MAF; HLTF; ZBTB18; BASP1; DNMT3B; NPAS2; SOX2; ZEB2; EDF1; MAGED1; HDAC4; NEDD8; RFX5; MEF2A; ZNF432; PAX6; ZMYM2; NR2F1; CARHSP1; FOXN3; POU2AF1; NR2F2; JARID2; SMARCA5; MEIS1; ZNF721; HTATIP2; TCF4; ZNF652; DRAP1; MTF2; PEG3; HOXC6; HLF; ERBB2; HMGN3; TLE1; PITX1; MTA1
Down-regulation 88 TULP3; MYC; SHOX; MYBL1; TAF5L; SNAI1; RAD21; FOXJ2; WWP1; BNC1; TEAD4; FOXF2; IRF9; CBFA2T3; ING4; NFATC4; MED21; NRIP1; CDK2; ZNF239; THAP7; LEF1; SMARCA2; THAP10; ACTL6A; NR5A2; CREBL2; SNAI2; TBX3; FOXM1; DLX5; ARID5B; DEK; ZFP36L2; KLF10; HDAC9; PRRX1; SPDEF; CCNH; IRF6; VDR; HIRA; TFAP2C; IFI16; OVOL2; GATA6; ARNTL2; DDIT3; TFAP2A; KAT2B; YEATS4; EYA2; TRPS1; KLF9; TWIST1; HSF1; ZIC1; CTBP2; SOX9; SSBP2; VPS72; NR0B1; JUNB; MED15; ATF3; TOX; EPAS1; ZNF12; HOXD1; CEBPD; KLF4; TRIM29; JUP; ARL2BP; RUNX1; OSR2; TCF21; NR1H2; JUN; SOX17; NR1D2; CEBPB; FOSB; TOB1; ETV5; NFKBIB; ESR1; ABL1