Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80124 Plumbagin GSE92742 NEU Human 24h 10uM EID0477
Types Number Response transcription factors
Up-regulation 182 CREG1; IKZF1; TTF2; ETV1; ACTL6A; MED21; PNRC1; HINFP; TAF4B; SOX17; OVOL2; TCF21; FOS; TP73; CCNH; MXI1; ZNF225; TFAP2A; HLX; ATF3; PCBD1; ZNF223; PCGF1; ZNF593; ZNF141; ZNF155; YEATS4; PTTG1; ZNF335; KAT2B; HESX1; PRDM14; ZNF835; ZKSCAN4; DDIT3; E4F1; BAZ2A; TBX21; POLR3C; CDIP1; ZNF132; ZNF34; NR1I3; RING1; CREBL2; IRF6; RFXANK; E2F4; NCOA2; PROP1; ZNF74; THRA; NFE2L2; SUPT3H; NR1H4; CDK7; PTRF; DAXX; HDAC9; TULP2; PEX14; LYL1; MED25; SOX18; MED15; BARX1; NR0B2; CDK2; NOC2L; THAP7; CDX1; ZNF239; TDP2; CCDC59; ZNF557; CNOT3; ELF3; IRF3; ZSCAN9; SPDEF; AHR; NFATC4; ZNF623; CALR; ST18; LZTR1; NFYA; BRDT; VGLL1; SOX13; HOXD1; CAMTA2; HIF3A; BNC1; LIN28A; PIR; IRF1; VDR; WWP1; EPAS1; SALL1; MED14; NR0B1; ZNF180; TLE2; ETV5; ESR1; ZNF76; RAD21; HOXB2; JUP; JUN; FLI1; IRF7; COPS5; GATA6; ZNF222; PRMT2; FOXG1; NR5A2; SNAI2; BCL11A; RBPMS; CRYM; PHF1; TULP3; KLF6; TAL1; ZNF224; MYNN; KLF1; HHEX; GON4L; TBX1; NFE2; KLF4; ETS1; HBP1; BTG1; PFDN5; PRDM1; SLC2A4RG; SIRT7; PRRX1; EGR4; JUND; FOXF2; ZNF350; ATF5; TRIB3; CEBPG; TFEC; CBX7; NANOG; MAFF; STAT1; ZNF415; ELF4; HTATIP2; STAT4; TGFB1I1; HOXA5; HOXC10; BRD2; NR4A3; ZNF394; TGFB1; NR1H2; TRIP6; C1QBP; NFKBIB; EHF; TP63; MEIS2; YBX3; TRIM22; FOXF1; MECOM; CREM; GMNN; TRPS1; EMX2
Down-regulation 340 BASP1; SOX4; ZMIZ1; RFX5; KMT2A; BAZ1B; DMTF1; SFPQ; KAT6A; SMARCC1; FOXO3; TOX3; SREBF1; ZBTB18; SOX2; PARP1; PATZ1; BIRC2; CHD1; TBL1X; BTAF1; RBPJ; ZNF292; FOXJ3; ZNF146; MGA; KAT6B; RBBP4; SNW1; CBX5; VEZF1; FUBP1; TSC22D2; ZNF189; CENPF; PHF2; ZMYM2; PIAS1; MTF2; TAF1D; TSC22D3; ZNF84; NUP62; TRIM32; PBX1; ZNF107; HNRNPD; ZNF3; MED13; RNF4; HMG20A; FOXO1; REPIN1; ZBTB1; SMARCA5; MAX; MED1; NCOR2; TERF2; SIM2; RARA; DNMT3B; CUX1; ZNF629; BRD3; BRD7; KDM5B; ZNF117; TULP4; NCOA4; NR2F2; EZH2; ZNF24; BCLAF1; ARID4A; SUZ12; ZBTB14; RUVBL1; PHF20; PCGF2; KDM2A; JARID2; RFX7; PIAS3; TSC22D1; CEBPZ; GABPB1; ZNF532; ZKSCAN7; ZNF23; ZNF654; BBX; ATF7IP; ZMYND8; CHD9; CHD7; HIVEP2; TRRAP; FOXN3; ZNF217; CENPB; CTR9; CHD4; RAN; ZNF273; MAGED1; MTF1; TTF1; TBL1XR1; SMARCA4; RCOR3; ZNF672; ZNF302; AFF1; TCF4; TBP; HSF2; TRIM33; ZNF443; KMT5A; HCFC1; SP3; SETD2; MED23; RFC1; PAXBP1; RHOA; TRAK1; NFKBIA; EP400; RBM14; ADNP; ASCL1; ZNF281; TCF15; NPAT; BRCA1; ZNF510; BRPF1; KDM4A; SAP130; EP300; ZNF14; NFAT5; CCNC; FOXO4; SETD3; VGLL4; HMBOX1; TGIF2; TRIM28; ZNF211; ECD; E2F3; SMAD2; IKBKAP; SMAD3; ZNF516; DDX5; STAT3; MLX; PURA; RNF10; CREB1; CCNA2; UBE2I; PRKDC; KDM5A; BRD8; HSBP1; DPF2; ARID1A; CREBZF; ZNF562; ZNF248; TEAD1; ZEB1; WWC1; NFATC1; MNT; UBE3A; ELF1; NEDD8; SMAD4; NCOA1; ERBB2; ZBTB24; RBBP7; MLLT10; TCERG1; ZEB2; MMS19; EDF1; ZMYND11; ATF2; KLF7; MYT1L; PKNOX2; NRF1; BAZ2B; BCL10; NFE2L1; CHD3; CTCF; MECP2; PSMC3IP; NFYC; RLF; PAX5; TLE1; ZFP64; EYA1; RYBP; ID3; SMARCE1; NR2F6; SMARCD3; HLTF; RB1; ZNF22; GTF2IRD1; TCF7; NLK; CREB3L1; TAF1A; FLNA; ZNF711; RBM39; CBX6; SAFB2; PIAS2; SMAD5; NAB1; RNF111; BACH2; TSC22D4; ZNF587; PSPC1; RCOR1; NFIB; MLXIP; CBFB; MED6; ZHX3; POU3F2; EGR3; ZNF468; MTA1; YWHAB; SSRP1; SAP30; HDAC2; BMI1; OLIG2; NONO; MITF; SF1; BCOR; USP16; SP110; TCF12; DEAF1; ZFP36L1; SOX10; ZMIZ2; BCL11B; CREB5; PBRM1; IRX5; PKNOX1; ZBED1; ZNF268; HOXB7; ZBTB43; CRY1; ZFHX4; SIX2; ZNF177; UBP1; PCGF3; ARID4B; RNF138; APBB1; MSX1; ZNF267; BAZ1A; WHSC1; NPAS2; PHF8; ELK3; ING3; ZNF160; HMGB1; CARHSP1; BCL6; TLE4; PPARGC1A; GLI2; ZBTB20; ZFP30; ELK1; ID2; PITX2; CTNNB1; BCL3; MYCN; THAP11; ENO1; CREB3L2; SIX1; PQBP1; ZNF131; FOXC1; ARNTL; ZKSCAN1; SMAD6; HOXC6; YBX1; ZNF423; HOXA11; ZNF721; RUNX3; HIC2; RORA; MYB; SMARCA1; HDAC4; SALL2; NRIP1; LEF1; BATF; SPEN; TBX3; MYRF; ZNF430; IRF4; TXNIP; ETS2; ZNF586; CRK