Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80118 Oxamflatin GSE92742 NEU Human 24h 10uM EID0477
Types Number Response transcription factors
Up-regulation 141 CREG1; CALR; MYCBP; GTF2A2; DAXX; MXI1; PTTG1; ETV5; TAF4B; GTF2F1; ZNF235; LHX3; NOC2L; TAF5; CRYM; SUPT5H; JUN; AIRE; ABT1; NFIC; HHEX; DRAP1; IRF1; ATF6; ATF3; PTRF; MLX; IRF3; PPARD; TCF21; IRF6; OVOL1; MED25; TCEA2; BRD2; KLF6; CDK7; TEAD3; TULP2; ASH1L; TAL1; CCNH; AR; ACTL6A; TULP3; ZNF593; BRF2; CREB3L2; CCNC; TBX19; INSR; PHF1; RXRB; TRIP4; LZTR1; SPIB; FOS; COPS5; ZNF557; LHX6; THAP7; OVOL2; HDAC1; RBPMS; CITED2; ESR1; MYBL1; CREB3L1; OSR2; PITX1; NR0B2; RUVBL2; SUPT4H1; WT1; NFE2; SIRT7; SSBP2; DBP; KLF2; BRD4; ELF3; TFAP2A; PIAS1; LITAF; PBXIP1; FLI1; HMG20B; POU2AF1; TCFL5; SUB1; RBBP5; SP100; IRF7; STAT1; ELK3; C1QBP; CBX7; ZNF239; JUNB; NR2F1; NR1H4; TFAP2C; SOX9; WWTR1; PFDN5; TDP2; NR0B1; JUND; RBBP8; NKX2-1; ZNF274; ZBED2; CTR9; E2F8; CBX6; SPDEF; ZNF544; ZNF350; PRPF6; LOXL2; PURA; LMCD1; NKX3-1; KLF4; MAFF; FOXA1; HOXA5; ETS1; BNC2; TP63; HDAC9; CEBPD; SLC2A4RG; NFKBIB; YBX3; SMARCA1; ZNF394; GMNN; BHLHE41; TRIB3; TRIP6
Down-regulation 283 BASP1; ZMIZ1; SMARCA4; USP22; PATZ1; SOX11; ERBB2; ZNF532; ZMYM2; TSC22D3; DMTF1; SMARCC1; ZNF189; ADNP; NUP62; ZNF629; PUF60; HDAC6; MTA1; ZKSCAN7; ZNF292; CBX5; TCF15; MNT; ZNF146; ZBED1; REPIN1; CUX2; BAZ2B; FOXO1; PHF20; NR2C1; ZBTB1; PHF2; TRAK1; ARID4A; NFKBIA; SMAD3; VGLL4; ZMYND8; SFPQ; ZNF84; ZEB2; TLE1; BRD3; PRRX2; DDX5; MDFI; FUBP1; NHLH2; ZBTB14; TCF3; ZFX; BCOR; CHD1; ZFP64; ZIC1; KMT2A; HR; TBL1X; NFIL3; ZNF529; FOSL2; HDAC2; XBP1; MLXIPL; MAML1; NHLH1; CENPB; TSC22D1; KAT6B; ZNF358; RFX7; SNW1; RARA; ATF7IP; GABPB1; CHD3; ARID1A; BCL11B; DNMT3B; STAT6; CENPF; WIZ; IKBKAP; SMARCA5; ERCC3; ZNF646; NCOR2; RUVBL1; MYOG; ATF2; NFYB; SALL1; TFCP2L1; EYA1; HMGB2; MEIS1; CTCF; ZNF83; GTF2IRD1; HMGB3; MYCN; TOX; NCOA2; CUX1; MEOX2; RLF; RAN; ZNF33B; VAX2; SMAD7; BPTF; GLI3; SMAD6; JARID2; UBE2I; OLIG2; TRRAP; HOXB3; ID4; HMGXB4; KDM5B; ARID5A; ARID3B; CDK8; VEZF1; HSBP1; DLX5; IKZF5; ZMYND11; NAB1; SMARCD1; HSF2; INSM1; PAXBP1; SMARCD3; SUV39H1; MGA; BCL10; KLF3; KAT7; TP53; PBRM1; RBM14; PLAGL2; NRIP1; ZNF248; HMG20A; RBBP4; ZNF24; PCGF3; ZEB1; CREB1; KAT8; HMGN3; RCOR3; SCAND1; CTBP1; HMGB1; EGR2; BACH1; GRHL2; FOXO3; BCLAF1; ZNF711; TCERG1; GLI1; HNRNPD; PIAS2; HDAC7; RBBP7; TCF4; SP3; KDM2A; ZZZ3; SMAD4; MECOM; SMARCE1; IRF8; COPS2; POU3F1; TGIF2; TCF12; NFE2L1; CBX3; PKNOX1; TAF1D; RNF10; BCL11A; MED13; ZNF443; CCNA2; YAF2; GTF3A; POU3F2; HIVEP1; GLI2; MED1; RBM39; ID3; E2F5; ESRRG; PLAG1; ZBTB18; SALL2; DDX17; MYT1L; HIC2; EGR3; SAP30; DACH1; ZNF160; ZBTB20; MAGED1; SIM2; CHD7; PCGF2; TCF20; EYA2; NR4A1; MTF2; BAZ1A; MEF2A; RCOR1; BBX; ZNF267; ZNF516; ZHX2; SIX2; TULP4; E2F3; HMGA2; TBL1XR1; SMAD2; CRY1; HDGF; TLE4; RNF138; SETD2; PLAGL1; TCF7; HAND1; YBX1; HOXB6; NR1I2; PSPC1; ZNF93; HEY1; ASCL1; ETV1; UBP1; CBFB; ZNF43; PHOX2B; NCOA1; TRIM22; NFAT5; ISL1; BATF; HIF1A; FOXC1; ID2; ZNF721; ZNF430; TRPS1; GATA6; LEF1; ETS2; ZBTB38; SATB1; BTG1; MYRF; TRIM16; ZNF423; HOXC6; TRIM29; TXNIP; BMI1; ARID4B; ZNF131; NFIB; ZNF586