Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID80069	Chloroquine	GSE92742	NEU	Human	24h	10uM	EID0477

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	OVOL1; LHX3; AIRE; ATOH1; BARX1; RBPJL; NFE2L2; NOC2L; EN1; MAP3K10; PRDM14; HIRA; TCF21; TBX21; ALX4; HMGB3; HEYL; TOX4; EVX1; RFXANK; PNRC1; TFAP2A; PBX3; CDX1; PIAS4; NR0B2; PAX6; MXI1; KLF6; SOX21; HLX; CEBPE; TULP3; MED25; PSMC3; HOXC8; FOXD1; MED16; CDIP1; IRF6; LIN28A; EPAS1; PARP1; GATA1; ATN1; TLX1; NFATC4; BTG1; NR5A2; RARG; SOX13; YAP1; VGLL1; GATA4; E4F1; ATF5; RXRA; PTTG1; SNAI1; GATAD2A; TCF7L2; TCF7L1; ZFP36L2; FLI1; KMT2D; ETS1; NKX2-2; ZNF232; TAL1; NR1H4; ID4; SIX3; HDGF; GATA6; ESR1; KLF7; ERG; GFI1; DBP; CTBP2; HHEX; TWIST1; CEBPG; HOXA1; DLX2; WHSC1; POU2AF1; WT1; NFE2; IRF1; NR0B1; PRPF6; TEAD4; NEUROD1; BCL11A; SOX9; FOXF1; INSR; SCAND1; FOXL2; ID1; ARL2BP; OSR2; NKX2-1; MEIS2; YBX3; WWTR1; ARID5B; MYB; RBPMS; IRX5; HEY1; AEBP1; NFKBIB; PEG3; MAFB
Down-regulation	221	MTA1; HDAC6; PHF20; BASP1; NUP62; TSC22D3; PATZ1; PSIP1; CHD1; FOSL2; MGA; NFIL3; CENPB; TLE1; BBX; ZNF107; ZNF12; ZNF23; TRIM32; IKBKAP; ZBTB18; EED; NR2C1; XBP1; CDC5L; ZNF189; ZNF146; ZMYM2; GTF2IRD1; ECD; BAZ1B; PSMD9; ZMYND8; ADNP; ZNF84; BTAF1; ZNF184; MLX; TAF1D; CUX1; HMGA1; DMTF1; FOXJ3; ARID5A; SP3; BCL10; SMAD3; SMARCA5; NFYB; RNF10; MDM2; ZNF672; PHF2; SMAD7; ZBTB11; ZBTB1; CENPF; ZZZ3; TRIM22; NFIB; CRY1; SNW1; EGR3; SREBF1; ELF2; TRRAP; MED4; ZNF813; KDM5D; MED23; SETD2; ERBB2; SAP18; PPARGC1A; ATF2; MTF2; ZNF281; SFPQ; RBM14; RREB1; MITF; STAT3; ZNF3; BRD8; TFCP2L1; DDX54; ZNF529; TSC22D1; BAZ1A; ARID1A; SMAD2; TBL1X; TOX; KAT6A; REPIN1; HLF; DNAJC2; FOXO1; HMG20A; ZNF443; PLAG1; SOX10; HLTF; ZNF629; TEAD1; SOX12; ZNF468; PMS1; HSF2; NFAT5; TOPORS; LIMD1; ZNF248; SP140; CHD9; ZEB2; ARID4A; NCOA4; TRIM28; ORC2; RNF6; TMF1; CTR9; REST; HIVEP1; BAZ2B; CCNT1; HMGN3; BRD7; E2F3; NR2F2; ZNF580; TRAK1; SMARCD3; TAF6; SMARCA2; NCOR2; C1D; ZNF267; PSPC1; RAN; PAXBP1; BCLAF1; ZNF304; CALCOCO1; NAB1; NR4A1; RNF111; ZMIZ2; BCL3; ZNF14; PHF8; IL16; ZBED1; ZNF226; BLM; BPTF; TDRD3; UBE2B; TERF2; TGS1; CHD3; LPIN2; JARID2; ZNF83; TAF4; FUBP1; FOSB; ZNF587; NKRF; AHR; MEIS1; MED6; GTF3A; STAT6; TGFB1I1; MEOX2; FOXC1; SMAD4; NR3C2; BRD3; NR1H3; KAT8; NRIP1; NCOA2; ZNF266; ING3; ZNF410; IRF7; RBBP5; EP400; UBP1; TSC22D2; SAP30; ZBTB16; MYT1L; DEK; MAGED1; ZNF24; CDK8; SP100; CERS6; MTDH; CBX6; RORA; ZNF134; TFEC; PRKDC; ZBTB38; SATB1; ERBB4; ZKSCAN1; NR2F1; EHF; TRIM16; ARID4B; PLAGL1; MED1; TRIP6; ID2; SMAD1