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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID80040 Hydroxychloroquine GSE92742 NEU Human 24h 10uM EID0477
Types Number Response transcription factors
Up-regulation 147 AIRE; TCF21; ALX4; HEYL; ATOH1; LHX3; GFI1; OVOL1; PARP1; THAP3; TBX21; TLX3; PBX3; BARX1; ZNF771; CEBPE; KLF6; MAP3K10; EVX1; NFE2L2; EN1; HIRA; RFXANK; RBPJL; LHX5; NPAS1; SOX9; GATAD2A; AEBP1; TFAP2A; HLX; MBD3; GATA6; POU2AF1; NOC2L; SOX21; ARL2BP; PDLIM1; PRRX2; HDAC11; PRDM14; TCF7L2; PROP1; HMGB3; MED25; NFATC3; TOX4; FOXD1; PNRC1; GATA1; YAP1; SUPT3H; PSMC3; MDFI; HOXC8; VGLL1; TLX1; MAPK8IP1; SNAI1; BNC1; TULP3; ILF2; HOXB1; INSR; SCAND1; PAX6; BTG1; CDX1; ID4; NR0B2; MXI1; SIRT2; MXD4; CREB3L2; TWIST1; ZNF711; SOX13; KMT2D; ATN1; IRF1; GATA4; ZNF232; NFKBIA; ID3; ZBTB32; WT1; ATF5; FOXL2; MED16; ENO1; NKX2-2; RXRA; UTF1; CDIP1; WWTR1; TAF12; SIX3; EPAS1; IRF6; LIN28A; TAF9B; MSC; PCGF3; NR5A2; ZNF576; TEAD4; HOXA11; HOXA1; PQBP1; NR0B1; SIRT7; MYRF; IRF8; PITX2; POU2F2; NEUROD1; AATF; DLX2; TCF7L1; ZFP36L1; MAFB; ETV4; ARNTL2; UBE2I; ALX1; VDR; CARHSP1; WHSC1; ZBTB7A; ZFP36L2; SPDEF; ID1; OSR2; IRX5; ETS1; KDM5A; ERG; ZBED2; PEG3; HHEX; ESR1; MEIS2; YBX3; MNDA; NKX2-1; ETS2; NFKBIB
Down-regulation 259 BASP1; MTA1; ZMYM2; PATZ1; PSIP1; PHF20; HDAC6; NR2C1; NUP62; MGA; KAT8; TSC22D3; SAP18; XBP1; NCOA2; CHD1; MITF; TFCP2L1; ZNF529; ZNF107; ZNF84; TLE1; SREBF1; ZBTB18; FOSL2; RNF10; ZNF23; ERCC3; EED; CENPB; NFIL3; ARID5A; GTF2IRD1; ZNF12; HMGA1; IKBKAP; DMTF1; BBX; SMAD7; ZZZ3; ZNF146; CALCOCO1; TRIM32; SNW1; RFX5; ZNF189; ZNF184; CDC5L; ECD; BTAF1; BAZ1B; FOXJ3; MAML1; TDRD3; MYCBP; ZBED1; ZNF83; RREB1; SETD2; ZNF281; PSMD9; KAT6A; ADNP; TSC22D1; MED23; ZMYND8; SP100; TRIM28; TAF1D; TOX; ZBTB16; TRIM24; BCL10; MLX; REPIN1; KDM5D; BAZ2B; SP3; CNOT3; HLF; TRIM22; GTF3A; ZNF473; SMAD2; ERBB2; CUX1; SMAD3; CREB5; NR3C2; ELF2; NR1H3; PLAGL1; HMGXB3; CCDC59; PLAG1; ZNF813; SMARCA5; BAZ1A; TRIM33; TGS1; PPARGC1A; ZBTB11; PHF2; CIR1; CENPF; BRCA1; NFYB; MED4; ZNF672; ZNF587; ORC2; ZFHX3; MTF2; ZBTB1; BCL3; TFEB; SFPQ; DNAJC2; EGR3; GRHL2; TRIP4; TGFB1I1; CDK8; ZNF266; CRY1; LIMD1; NFIB; HLTF; YBX2; NKRF; SOX12; PAXBP1; TAF4; STAT6; BRD8; IL16; ZNF24; CHD3; PCBD1; MEOX2; HIVEP1; TRRAP; RELA; ZNF304; ZNF580; ZNF248; NR4A1; SOX10; CTR9; FOXO1; RNF138; TBL1X; BPTF; PMS1; PSPC1; HDAC2; BLM; SP140; NFAT5; RBM14; DEAF1; MEIS1; CCNT1; ZNF3; YAF2; NCOA4; PIAS2; MEOX1; ZNF443; ZNF268; PAX5; TOPORS; C1D; BCOR; RNF6; NCOA3; DDX17; ZNF467; AHR; CREBL2; CHD9; REST; STAT5B; BCLAF1; HMG20A; SMARCA2; TCF7; DEK; LPIN2; IRF7; TMF1; MTDH; TEAD1; RNF111; ZNF468; SMARCC2; ZEB2; FOSB; ATF1; NAB1; SIX1; E2F3; ARID4A; SMARCD3; TFEC; HMGN3; SMAD4; ZNF512B; TRAK1; UBTF; ISL1; HMGA2; MED6; NCOR2; ZNF267; CBX3; ZNF140; NR2F2; YBX1; ZNF331; ZNF419; NPM1; NRIP1; JARID2; CERS6; FHL2; TADA3; ZNF410; ENY2; RBBP8; ZNF134; CDYL; CITED1; RORA; ELK3; SMAD1; PCGF2; TGIF1; NR1D2; ATF3; ZNF606; LOXL2; UBP1; ARID4B; NCOA1; GMNN; JUP; REL; TP63; EHF; TRIP6; EMX2; TRPS1; NR2F1; ZSCAN18; NKX3-1; MAGED1; TRIM29; ZKSCAN1
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