Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79918 Pyrvinium GSE92742 NEU Human 24h 10uM EID0476
Types Number Response transcription factors
Up-regulation 266 VGLL1; ACTL6A; ELK4; HHEX; NR1H2; SOX17; ZNF394; TLE2; YEATS4; TAF1C; E2F4; IRF6; JUN; CCNH; PRMT2; ZNF117; BNC2; TEAD3; FOXF2; SOX13; ESR1; THRB; ATF3; PROP1; WWP1; ZNF557; GATA6; HLX; BNC1; TULP2; ZFPM2; MYBL2; NFKB2; IRF9; RFXANK; PBXIP1; TTF2; ZFX; JUNB; TRIM22; E2F8; SOX18; FOS; SKIL; TBX21; CEBPD; RB1; PSMC3; KLF4; MAFF; MYNN; TAF5L; MYBL1; PRDM14; SHOX2; BTG1; BHLHE41; NR5A2; KLF15; HIF3A; CREM; HOXA4; NR4A2; ZNF556; KLF6; PPARD; TFAP2A; ERG; IRF1; FOXE1; TAF6L; ZNF235; RAD21; EPAS1; NFYA; GLI2; HOXA1; TCF21; ATF6; ZNF507; ZNF816; GRIP1; CEBPB; TBX5; ZNF343; SOX14; MEF2C; NR0B1; TAF9; TULP3; EGR4; CDK2; ZNF623; TFDP3; IFI16; SIX5; ERBB4; ZKSCAN4; HOXA5; TBX1; KAT2A; EGR1; SSX7; AR; ZNF74; HDAC9; LZTR1; NR2F6; NFE2L3; TRPS1; CDX4; REL; ZNF345; ZNF154; PNRC1; RBL2; HOXA6; CBFA2T3; PCBD1; HOXD13; ZKSCAN3; ZNF770; NFE2L2; MED20; PRRX1; EMX1; AGO2; EHF; RELA; MYCL; STAT1; TP63; FOXJ2; CREB1; PRDM2; SPDEF; GATA4; HEYL; RING1; EMX2; CDK7; ARID5B; NFE2; PGR; MED21; HOXB5; NR1H4; MSC; TGFB1; TAF5; GTF2A2; FOXL2; ELK3; BARX1; PAWR; RARG; HTATIP2; ZNF276; AEBP1; CDK9; BLZF1; MYC; ZNF695; KLF9; TRIP6; ZHX2; SRY; ETS1; TERF1; TAF11; CEBPG; POLR3C; TFEB; ZBTB16; IFNB1; SOHLH2; ZNF215; WT1; ZNF350; E4F1; SNAI2; NFATC3; NR1I3; OVOL2; ZNF224; ZNF692; YBX3; FOXN3; SUPT3H; CREB3L2; KLF13; NR4A1; ZNF232; VPS72; TGIF2; SMARCA1; TAF7; KLF11; HOXB2; RBL1; TEAD4; ATF5; IRF3; IRF2; MXI1; TAL1; ZBTB3; FLI1; CCNT1; ARL2BP; NR4A3; SRF; LMCD1; TFDP2; ELF4; NFYB; YEATS2; CALR; TERF2; SMARCA2; ZNF331; ZNF589; TGFB1I1; EYA2; CDIP1; ARNTL2; CAMTA2; ZNF239; IRF4; BCL11A; ELF3; SLC2A4RG; NFATC4; NR0B2; THAP10; ZIC1; CLOCK; FOXF1; YAP1; ZBED2; ZNF22; HSF1; NR1D2; ZNF415; ZNF34; AHR; CCDC59; MYB; SSX1; JUP; LOXL2; ZFP36L1; FOSB; HOXD1; ETS2; CRYM; MDM2; FOXJ1; THAP11; TGIF1; HOXB6; PIR; WWTR1; ZNF467; PBX1; HIRA
Down-regulation 389 SOX4; BASP1; TOX3; USP22; VGLL4; DRAP1; FOXO3; NUP62; HDAC2; ATF4; KDM5B; TCEB2; SOX2; PCGF2; BAZ2B; NCOR2; SMARCA4; TRIM28; SMARCE1; SMARCA5; APEX1; HNRNPD; TAF10; NONO; ZNF292; GTF2IRD1; RBBP4; SMARCC1; RBPJ; MTF2; POU2F1; EDF1; TLE4; EYA1; ZMYND8; BRD8; SOX11; KDM5D; TRRAP; BCOR; CTR9; EZH2; JARID2; HDAC6; HDAC4; CAMTA1; UBTF; CARHSP1; YBX1; CHD4; NEDD8; KAT6A; MAGED1; CHD8; ZMIZ1; DEAF1; SMARCD3; ZMIZ2; MED23; KAT7; TOX; TBL1X; ZBED4; SFPQ; ATF7IP; HCFC1; ZNF3; PHF20; ZNF44; ADNP; NHLH2; ZNF24; CARM1; HSF2; SAFB2; ASXL1; KMT2A; SPEN; MEN1; MTA1; NACA; ZNF189; CCNC; DNMT3B; CITED1; TSC22D3; ZNF711; SND1; ENO1; KAT5; MED24; SNW1; ZKSCAN7; MAZ; CTBP1; PATZ1; BRPF1; PMF1; ZNF423; SP110; ZBTB18; TBP; USF2; THAP4; DPF2; RBM14; NCOA4; SMAD2; ZNF506; BRD3; POU3F2; ZNF516; ZNF226; TCF20; ZNF629; ZNF324; CHD7; EP400; TRIM33; E2F5; HMGN3; ZNF212; KAT6B; PQBP1; PHOX2B; RCOR3; CBX3; MYT1L; MED4; ADNP2; TCF12; MNT; ZNF532; RBBP7; ZNF443; PSIP1; EGR3; KDM4A; ZNF248; RLF; BTF3; COPS2; HSBP1; CBX5; ZFY; MED1; PSPC1; KMT5A; ZNF606; SMARCB1; NELFB; TRAK1; SCMH1; HMGB3; PRKDC; RNF10; HLTF; ZNF536; TAF1D; SREBF1; ARID1A; PHF2; NFYC; PKNOX1; PBRM1; RFX7; ZNF358; TAF9B; YWHAB; ZNF263; ZNF266; GLI3; ZNF419; TOPORS; IKBKAP; ZNF574; HAND1; AATF; APBB1; ID2; KDM2A; SP2; SOX9; ZNF529; HMGXB4; FOXO4; SOX12; TCF25; UBE2I; TBL1XR1; GMEB1; BCLAF1; HMGA1; TCF7; HMG20B; MBD4; RCOR1; TP53; IRX5; PLAGL1; CUX1; MDFI; BAZ1B; WHSC1; CBX8; GTF3A; EP300; ZNF787; SETD2; PSMD9; HDAC1; ZNF84; ARID3B; CBX4; NCOA6; ZNF14; ZNF468; SIX1; TULP4; SNIP1; MYT1; PIAS2; HIC2; RFX5; ZNF446; CENPB; ORC2; BBX; ZNF587; PPARGC1A; HIVEP2; BAZ1A; UBE3A; ZNF384; RNF4; ING2; ZBTB24; ZFHX4; PIAS1; NCOR1; SAP18; ZNF43; ELF2; ZFP64; CHD1; TRIM24; INSM1; KLF12; RUVBL2; KDM5A; MAFG; SMAD6; ZNF334; SOX10; CTNNB1; ARID4A; TCERG1; WWC1; USP21; TSC22D1; ARRB1; SSRP1; CREBZF; UBP1; CHD3; VEZF1; NFIB; BCL11B; PAXBP1; RARA; SUPT6H; TADA3; ZBTB11; SCAND1; E2F3; GABPB1; DNAJC1; NAB1; TFE3; FOXG1; ZMYM2; MTF1; BMI1; KAT8; ZNF23; NFIL3; ZNF211; FOXC1; FOXD1; C1QBP; LDB1; SIX2; NR2C1; ISL1; TBPL1; NFE2L1; ZNF672; ASCL1; FUBP1; ZEB2; TSG101; EWSR1; UBE2B; PTTG1; ZNF45; PRPF6; FLNA; ZNF146; ZNF302; PAX5; PA2G4; REPIN1; ZNF8; CHD9; ZNF143; MLX; EN2; CENPF; SMARCD1; TOB1; ETV1; MAX; TRIM32; EHMT2; ZBTB7A; ETV4; NPAT; MXD4; SIX3; NR2F2; RYBP; MED6; ERBB2; PLAGL2; ZBTB1; RAN; HR; DAXX; BTAF1; GTF2I; BIRC2; ZBTB20; NFATC1; ZBTB43; MSX1; SMAD7; ZNF721; NR2F1; SUB1; BACH2; TLE1; HMBOX1; HMGB1; ZNF304; SP3; NFAT5; PCGF3; ZNF646; HLF; BRD2; URI1; PUF60; GATAD2A; ID3; TBX3; MEF2D; DDIT3; NRIP1; SAP30; LPIN2; TSC22D2; POU2AF1; ZNF551; RREB1; MYCN; ABL1; ZNF134; KLF5; ZNF217; ID4; ZNF544; ZNF586; ZNF671; ARID4B; MAFB; HOXC6; CRK; SUV39H1; ID1