Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79896 Pyridine-2,4-dicarboxylic-acid GSE92742 NEU Human 24h 10uM EID0476
Types Number Response transcription factors
Up-regulation 93 SMARCA2; TBP; SOX2; REST; ING2; ELK3; BATF3; BRD8; HLTF; NCOA1; ZNF226; BMI1; NCOA4; ORC2; BAZ2B; POLR2A; DNAJC1; ZMIZ2; PPARGC1A; KDM2A; ZEB2; ING3; HABP4; JARID2; CTR9; PSPC1; TRIM28; ARID5B; EDF1; HSBP1; NRBF2; FOXJ3; RLF; SNIP1; ARID4A; ZNF14; HSF2; TSC22D4; FOXL2; AFF1; OLIG2; ZBTB18; NFYC; HDAC6; KAT7; CHD3; BRPF1; FOXO1; BRD3; NEDD8; USF2; IRX5; GABPB1; PHF8; CITED2; MED1; ZNF45; DNMT3B; HOXC6; ZMYND11; NAB1; DNAJC2; SSX1; MAF; ZNF148; MEIS1; SF1; ELK1; TGIF1; NCOA6; LEF1; LPIN2; MAGED1; ZNF281; HDAC7; NFIB; SATB2; SCAND1; TCF4; PIR; RNF6; SSBP2; SAP30; SAP18; MAFB; ABL1; PBX1; ERBB2; TSC22D1; NR2F1; TLE1; CRK; ZMYM2
Down-regulation 63 TRIB3; MEIS2; IRF6; TOX; VGLL1; NR1H2; CEBPD; PSMC3; GATA6; ETS1; SIX6; TFEC; TAF9; CBFA2T3; IFI16; ZIC3; HOXB13; FOXA2; KLF4; FOXF2; PTRF; GRHL2; SPDEF; BNC2; RAD21; SPIB; KLF6; ZBED2; NR5A2; KLF7; FOXM1; ATF3; CDIP1; FOXE1; TFAP2A; PHIP; NR4A2; CSDE1; SMAD1; SIX3; IRF9; ZNF331; ST18; INSM1; MYBL1; TDP2; SOX17; INSR; NKX2-1; SOX9; PAWR; HDAC9; SNAI2; FOXF1; ZNF544; BCL11A; HIRA; ARID4B; ZNF83; ZNF264; AEBP1; ESR1; ISL1